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Procedure: Perfusion
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Unilateral vanishing lung syndrome
A 14-year-old boy was admitted with mild right chest pain, exercise dyspnoea and occasional palpitations. There was no smoking history. There was no past medical history of recurrent chest infections. The physical examination revealed an absence of breath sounds and hyper-resonance of the right hemithorax. A chest X-ray showed unilateral massive bullous disease with radiolucency of right lung and flattening of the right hemidiaphragm (figure 1A). The high-resolution chest CT scan confirmed air herniation towards left side with mediastinal shift resulting in airway displacement (figure 1B, C). A significant reduction of rig...
Source: Thorax - June 13, 2016 Category: Respiratory Medicine Authors: Anile, M., Diso, D., Onorati, I., Mantovani, S., Venuta, F. Tags: Images in Thorax, Journalology, Child health, Cardiothoracic surgery, Radiology (diagnostics), Ethics, Health education, Smoking, Tobacco use, Tobacco use (youth) Chest clinic Source Type: research
Perfusion alterations reveal distinct patterns of early vulnerability to damage across the ALS-FTLD continuum (P2.087)
Conclusions:Orbitofrontal hyperperfusion in bvFTD suggests compensatory responses to early decline in regions related to behavioral control, while marked cingulate hypoperfusion in patients with dementia is consistent with greater vulnerability of cognitive hubs to decline in these phenotypes. These findings indicate that the interplay among atrophy and perfusion changes may inform different epicenters of pathology and mark distinct patterns of early vulnerability to degeneration across the ALS-FTLD continuum.Disclosure: Dr. Ferraro has nothing to disclose. Dr. Jester has nothing to disclose. Dr. Placek has nothing to disc...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Ferraro, P. M., Jester, C. A., Placek, K., Olm, C. A., Agosta, F., Elman, L., McCluskey, L., Irwin, D. J., Filippi, M., Grossman, M., McMillan, C. T. Tags: Frontotemporal Dementia Source Type: research
A multidisciplinary educational curriculum for the management of orbital compartment syndrome
Orbital compartment syndrome (OCS) is a time-sensitive, vision-threatening emergency due to elevated intraorbital pressure, resulting in decreased perfusion of the optic nerve and retina. Rapid diagnosis and management of OCS are vital for vision preservation as perfusion should be restored emergently to prevent permanent vision loss [1]. Multiple studies have identified the need for educational initiatives to educate Emergency Medicine (EM) providers on the management of OCS [2,3]. However, lateral canthotomy and cantholysis, the primary management of OCS, is not identified by the Accreditation Council for Graduate Medica...
Source: The American Journal of Emergency Medicine - December 8, 2019 Category: Emergency Medicine Authors: Austin Fox, Ben Janson, Heather Stiff, Anthony Chung, Matthew Benage, Jon Van Heukelom, Thomas A. Oetting, Erin M. Shriver Source Type: research
What Is the Classic Clinical Presentation of Pericarditis?
Discussion
The pericardium is a bi-layered membrane that envelops the heart and provides a barrier to prevent disease and also decreases friction as the heart moves. Pericarditis is the inflammation of pericardium. The incidence is underreported as asymptomatic or mild disease may go unrecognized. From hospitalized patient data, 0.2-5% of patients with various cardiac disease had pericarditis. An incidence rate for hospitalizations of 3.32 per 100,000 person years has been cited. Percarditis occurs more often in adolescent males.
Treatment of the underlying cause or suspected cause is important, along with close monitorin...
Source: PediatricEducation.org - January 13, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
What Causes Tachycardia?
Discussion
Tachycardia is a rapid heart rate that is above normal for age and level of exertion. Tachycardia is common, particularly sinus tachycardia due to normally encountered circumstances such as pain, fever or exercise. It is usually a normal physiologic process but sustained tachycardia often indicates a potentially abnormal underlying cause.
Sinus tachycardia has a rapid heart rate with normal P waves and P-R intervals and variations from moment to moment and respiration. Generally it is not over 200 beats/minute. Vagal stimulation can slow the heart rate; this is a gradual slowing, not an abrupt slowing seen in ...
Source: PediatricEducation.org - March 23, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
What are Some Risk Factors for Hypoxic-Ischemic Encephalopathy Outcomes?
Discussion
“Neonatal encephalopathy, manifesting as altered responsiveness, seizures, apnea and abnormal muscle tone and reflexes, resulting from hypoxic-ischemic injury is termed hypoxic-ischemic encephalopathy (HIE).” Neonatal encephalopathy can be associated with other problems including stroke, hemorrhage, infection, pre-term brain injury and hypoglycemia as some examples. Sometimes more than one of these entities occurs simultaneously such as hypoglycemia and HIE. HIE can result in long-term neurological problems including motor, behavioral, and cognitive problems that can become apparent even years later....
Source: PediatricEducation.org - December 13, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
A Cadaveric Training System for the Maintenance of Basic Microsurgical Hand Skill: Submersible Pump Perfusion System
Basic microsurgical education is provided by accredited courses. An additional training activity for the maintenance of the skill is needed even if the surgeon routinely performs microsurgical operations. Both ethical considerations and time limit necessitate a novel and easy training system that can be combined to surgical loupes for continued microsurgical education. Nowadays, different useful synthetic and cadaveric animal models based on different organs and vessels were defined for this issue.
Source: Journal of Surgical Education - March 30, 2015 Category: Surgery Authors: Nebil Yeşiloğlu, Emre Güvercin, Hakan Şirinoğlu, Gökhan Temiz, Murat Sarici Tags: Letter to the editor Source Type: research
SimLife a new model of simulation using a pulsated revascularized and reventilated cadaver for surgical education
Conclusion We present a technique of perfusion and ventilation of a fresh human cadaver that restores pulsatile circulation and respiratory movements of the model.
Source: Journal of Visceral Surgery - September 5, 2016 Category: Surgery Source Type: research
Infrapopliteal calcification patterns in critical limb ischemia: diagnostic, pathologic and therapeutic implications in the search for the endovascular holy grail.
This article attempts to review the implications of the diverse pathologic patterns of calcium distribution in infrapopliteal vessels of CLI patients, on the diagnostic modalities, technological developments, and the evolution of therapeutic approaches to improve outcomes among these patients. A critical analysis of the currently available data is provided, pointing to the surprising omission on the role of calcium on outcomes, and future directions are discussed. Is infrapopliteal calcium a roadblock or the avenue towards new paths? Necessity remains the mother of invention.
PMID: 28240525 [PubMed - as supplied by publisher]
Source: The Journal of Cardiovascular Surgery - February 26, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Mustapha JA, Diaz-Sandoval LJ, Saab F Tags: J Cardiovasc Surg (Torino) Source Type: research
Pre-clinical imaging for establishment and comparison of orthotopic non-small cell lung carcinoma: in search for models reflecting clinical scenarios.
Conclusion Our developed orthotopic NSCLC tumours have similarity with biological growth behaviour comparable to that seen in the clinic and could therefore be used as attractive models to study tumour biology and evaluate new therapeutic strategies. The use of human cancer cell lines facilitates testing of different genomic tumour profiles that may affect treatment outcomes. Advances in knowledge The combination of different imaging modalities to identify tumour growth with subsequent use in treatment planning and orthotopic transplantation techniques to develop initially single lesions to ultimate metastases pave the way...
Source: The British Journal of Radiology - September 14, 2018 Category: Radiology Authors: Aktar R, Dietrich A, Tillner F, Kotb S, Löck S, Willers H, Baumann M, Krause M, Bütof R Tags: Br J Radiol Source Type: research
Indocyanine Green Angiography in Breast Reconstruction: Utility, Limitations, and Search for Standardization
Conclusions:
ICGA can reduce postoperative tissue loss and aid in intraoperative flap design and inset. Despite the benefits of ICGA, its technical use and interpretation have yet to be standardized, limiting its widespread acceptance.
Source: Plastic and Reconstructive Surgery – Global Open - March 1, 2020 Category: Cosmetic Surgery Tags: Original Articles Source Type: research
Human anatomy education and management of anatomic specimens during and after COVID-19 pandemic: Ethical, legal and biosafety aspects.
Abstract
COVID-19 is an infection caused by the SARS-CoV-2 virus, initially identified in the city of Wuhan, China, in December 2019. Since then, the virus has spread to the continents, causing a major pandemic. The impacts of this pandemic on the education of human anatomy interfere in at least two aspects: (1) receiving and managing anatomical specimens in anatomy laboratories and (2) adaptations for classes on remote virtual teaching. Therefore, this study reviewed and discussed the legal and bioethical aspects, considering the scenario of a South American Country, aiming to stimulate the debate on these two re...
Source: Annals of Anatomy - October 2, 2020 Category: Anatomy Authors: Lemos GA, Araújo DN, de Lima FJC, Bispo RFM Tags: Ann Anat Source Type: research
Multimodal Microvascular Mapping for Head and Neck, Skull Base Research and Education: An Anatomical Donor Study
Conclusion A final combination of BaSO4, 3% agar, and fluorescein proves to be a powerful and novel combination enabling CT imaging, fluorescence imaging, and dissection of vasculature. This paves the way for future translational research and education. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Journal of Neurological Surgery Part B: Skull Base - March 1, 2021 Category: Neurosurgery Authors: House, Adrian E. Romano, Michael F. Orczykowski, Mary E. Zumwalt, Ann Devaiah, Anand K. Tags: Original Article Source Type: research
In search of optimal cardioplegia for minimally invasive valve surgery
Perfusion. 2021 Jun 3:2676591211012554. doi: 10.1177/02676591211012554. Online ahead of print.ABSTRACTCardioplegic solutions are used in cardiac surgery to achieve controlled cardiac arrest during operations, making surgery safer. Cardioplegia can either be blood or crystalloid based, with perceived pros and cons of each type. Whilst it is known that cardioplegia causes cardiac arrest, there is debate over which cardioplegic solution provides the highest degree of myocardial protection during arrest. Myocardial damage is measured post-operatively by biomarkers such as serum TnT, TnI or CK-MB. It is known that the outcomes ...
Source: Perfusion - June 3, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Sion Russell Salman Butt Hunaid A Vohra Source Type: research
