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New deadly strain of bird flu may have emerged
“Experts are concerned about the spread of a new strain of bird flu that has already killed one woman in China,” BBC News reports. The new strain, which has evolved from an existing bird flu virus called H10N8, has infected two people in China. A case report in The Lancet medical journal warns that potential for a new pandemic “should not be underestimated”. Their genetic tests of the strain suggests it has adapted to infect humans more easily.  That said, experts suggest there is currently no cause for alarm. There is no evidence that the new strain can pass between humans. Also, the woman who died of the ne...
Source: NHS News Feed - February 5, 2014 Category: Consumer Health News Tags: Swine flu QA articles Medical practice Source Type: news

Behind the Headlines Top Five of Top Fives 2014
As we move towards the end of the year, like all news sources, we fall back on that classic space filler – the list story. So without further ado, here is the official Behind the Headlines Top Five of Top Fives stories of 2014, in which we celebrate the good, highlight the bad, check out the weird and answer some of the burning questions of the year. The top five 'Good work boffins!' stories of the year We can often get bogged down in pointing out dodgy sub-group analyses, spurious extrapolations of sample sizes containing just 20 rats and a water maze, and RCTs pointing out the benefits of cherries on dementia preventio...
Source: NHS News Feed - December 31, 2014 Category: Consumer Health News Tags: QA articles Medical practice Source Type: news

Ectoparasites of medical and veterinary importance: drug resistance and the need for alternative control methods
Abstract ObjectivesDespite multiple attempts at eradication, many ectoparasites of humans and domestic livestock remain a persistent problem in the modern world. For many years, a range of pesticide drugs including organophosphates, organochlorides and synthetic pyrethroids provided effective control of these parasites; but intensive use of these drugs has led to the evolution of resistance in many target species. This paper aims to review the effectiveness of current control methods and discuss potential alternatives for the long term sustainable control of ectoparasites. Key FindingsImportant medical ectoparasites such a...
Source: Journal of Pharmacy and Pharmacology - February 3, 2015 Category: Drugs & Pharmacology Authors: Carol M. McNair Tags: Review Source Type: research

New chlamydia vaccine shows promise after being tested on mice
ConclusionThis animal research has tested out a potential new vaccine against chlamydia, which utilises UV light-killed chlamydia bacteria linked to tiny nanoparticles. The vaccine did protect against chlamydia infection in mice, if it was given directly onto the mucous-producing surfaces of the nose or uterus.Previous attempts to make a chlamydia vaccine have not been successful, and the current research also identified that this may have been due to the type of immune response produced. This new approach prompts a different immune response, including “memory” cells, which remain in the mucosal tissue. These cells pro...
Source: NHS News Feed - June 19, 2015 Category: Consumer Health News Tags: Lifestyle/exercise Medication Medical practice Source Type: news

Volume: 26 Issue: 4
This article documents the first case of TSS associated with the use of a menstrual cup in a 37-year-old woman. The authors also discuss the history of TSS associated with tampon use and the mechanisms by which menstrual cups may also lead to the syndrome. Avian influenza A (H5N1) infection with respiratory failure and meningoencephalitis in a Canadian travellerSince 1997, more than 600 individuals worldwide have been infected with the poultry-originating influenza, H5N1. This report describes the first case of avian influenza A (H5N1) in the Western hemisphere in a 28-year-old woman who had just returned from a trip to Be...
Source: Canadian Journal of Infectious Diseases and Medical Microbiology - December 23, 2015 Category: Infectious Diseases Source Type: research

Primate research is crucial if we are to find cures for diseases like Parkinson's
To effectively combat the scourge of neurodegenerative and other crippling diseases, we require the careful and considered use of nonhuman primatesNonhuman primates have long played a key role in life-changing medical advances. A recent white paper by nine scientific societies in the US produced a list of 50 medical advances from the last 50 years made possible through studies on nonhuman primates. These included: treatments for leprosy, HIV and Parkinson ’s; the MMR and hepatitis B vaccines; and earlier diagnosis and better treatment for polycystic ovary syndrome and breast cancer.The biological similarities between hum...
Source: Guardian Unlimited Science - September 13, 2016 Category: Science Authors: Letters Tags: Medical research Science Animal welfare Animals World news Animal experimentation Source Type: news

Evaluation of Medical Countermeasures Against Ebolaviruses in Nonhuman Primate Models.
Abstract Several ebolavirus species, with varying lethality rates, have caused sporadic outbreaks in Africa resulting in human disease. Ebolaviruses also have the potential for use as biological weapons. Currently, there are no licensed vaccines or therapeutics to respond to outbreaks or deliberate misuse of ebolaviruses. Vaccine or therapeutic efficacy testing of medical countermeasures against ebolaviruses requires an animal model of disease; in vitro testing in cell culture cannot reproduce the complicated balance between host-pathogen interactions required for the ultimate licensure of a countermeasure. Depend...
Source: Mol Biol Cell - June 3, 2017 Category: Molecular Biology Authors: Mire CE, Geisbert TW Tags: Methods Mol Biol Source Type: research

Health system preparedness & amp; community participation in Japanese encephalitis/acute encephalitis syndrome (JE/AES) prevention in a tribal district of Odisha, India
CONCLUSIONS: Community participation and coordination between different stakeholders have a significant impact on the successful implementation of the programme. It was suggested that there was a need for a sustainability approach to active participation, orientation and capacity building training among CHWs and community volunteers to successfully implement the programme.PMID:33907003 | DOI:10.4103/ijmr.IJMR_645_21
Source: The Indian Journal of Medical Research - April 28, 2021 Category: Biomedical Science Authors: Krushna Chandra Sahoo Sapna Negi Girish Chandra Dash Rakesh Kumar Sahoo Jaya Singh Kshatri Sheetal Panda Matrujyoti Pattanaik Goldi Badaik Sanghamitra Pati Debdutta Bhattacharya Source Type: research

Investigations of seasonal outbreaks of acute encephalitis syndrome due to < em > Orientia tsutsugamushi < /em > in Gorakhpur region, India: A One Health case study
Indian J Med Res. 2021 Mar;153(3):375-381. doi: 10.4103/ijmr.IJMR_625_21.ABSTRACTGorakhpur division consisting of Gorakhpur and neighboring districts Deoria, Kushinagar and Maharajganj in Uttar Pradesh, India, have been witnessing seasonal outbreaks of acute encephalitis syndrome (AES) among children for the last three decades. Investigations conducted during 2005 identified Japanese encephalitis (JE) virus as an aetiology of AES. With the introduction of JE vaccination and other control strategies, the incidence of JE in the region declined, however, outbreaks of acute febrile illness with neurological manifestations cont...
Source: The Indian Journal of Medical Research - April 28, 2021 Category: Biomedical Science Authors: Manoj V Murhekar Jeromie Wesley Vivian Thangaraj Candasamy Sadanandane Mahima Mittal Nivedita Gupta Winsley Rose Seema Sahay Rajni Kant Mohan D Gupte Source Type: research

Health system preparedness & amp; community participation in Japanese encephalitis/acute encephalitis syndrome (JE/AES) prevention in a tribal district of Odisha, India
CONCLUSIONS: Community participation and coordination between different stakeholders have a significant impact on the successful implementation of the programme. It was suggested that there was a need for a sustainability approach to active participation, orientation and capacity building training among CHWs and community volunteers to successfully implement the programme.PMID:33907003 | DOI:10.4103/ijmr.IJMR_645_21
Source: The Indian Journal of Medical Research - April 28, 2021 Category: Biomedical Science Authors: Krushna Chandra Sahoo Sapna Negi Girish Chandra Dash Rakesh Kumar Sahoo Jaya Singh Kshatri Sheetal Panda Matrujyoti Pattanaik Goldi Badaik Sanghamitra Pati Debdutta Bhattacharya Source Type: research

Investigations of seasonal outbreaks of acute encephalitis syndrome due to < em > Orientia tsutsugamushi < /em > in Gorakhpur region, India: A One Health case study
Indian J Med Res. 2021 Mar;153(3):375-381. doi: 10.4103/ijmr.IJMR_625_21.ABSTRACTGorakhpur division consisting of Gorakhpur and neighboring districts Deoria, Kushinagar and Maharajganj in Uttar Pradesh, India, have been witnessing seasonal outbreaks of acute encephalitis syndrome (AES) among children for the last three decades. Investigations conducted during 2005 identified Japanese encephalitis (JE) virus as an aetiology of AES. With the introduction of JE vaccination and other control strategies, the incidence of JE in the region declined, however, outbreaks of acute febrile illness with neurological manifestations cont...
Source: The Indian Journal of Medical Research - April 28, 2021 Category: Biomedical Science Authors: Manoj V Murhekar Jeromie Wesley Vivian Thangaraj Candasamy Sadanandane Mahima Mittal Nivedita Gupta Winsley Rose Seema Sahay Rajni Kant Mohan D Gupte Source Type: research

Health system preparedness & amp; community participation in Japanese encephalitis/acute encephalitis syndrome (JE/AES) prevention in a tribal district of Odisha, India
CONCLUSIONS: Community participation and coordination between different stakeholders have a significant impact on the successful implementation of the programme. It was suggested that there was a need for a sustainability approach to active participation, orientation and capacity building training among CHWs and community volunteers to successfully implement the programme.PMID:33907003 | DOI:10.4103/ijmr.IJMR_645_21
Source: The Indian Journal of Medical Research - April 28, 2021 Category: Biomedical Science Authors: Krushna Chandra Sahoo Sapna Negi Girish Chandra Dash Rakesh Kumar Sahoo Jaya Singh Kshatri Sheetal Panda Matrujyoti Pattanaik Goldi Badaik Sanghamitra Pati Debdutta Bhattacharya Source Type: research

Investigations of seasonal outbreaks of acute encephalitis syndrome due to < em > Orientia tsutsugamushi < /em > in Gorakhpur region, India: A One Health case study
Indian J Med Res. 2021 Mar;153(3):375-381. doi: 10.4103/ijmr.IJMR_625_21.ABSTRACTGorakhpur division consisting of Gorakhpur and neighboring districts Deoria, Kushinagar and Maharajganj in Uttar Pradesh, India, have been witnessing seasonal outbreaks of acute encephalitis syndrome (AES) among children for the last three decades. Investigations conducted during 2005 identified Japanese encephalitis (JE) virus as an aetiology of AES. With the introduction of JE vaccination and other control strategies, the incidence of JE in the region declined, however, outbreaks of acute febrile illness with neurological manifestations cont...
Source: The Indian Journal of Medical Research - April 28, 2021 Category: Biomedical Science Authors: Manoj V Murhekar Jeromie Wesley Vivian Thangaraj Candasamy Sadanandane Mahima Mittal Nivedita Gupta Winsley Rose Seema Sahay Rajni Kant Mohan D Gupte Source Type: research

Health system preparedness & amp; community participation in Japanese encephalitis/acute encephalitis syndrome (JE/AES) prevention in a tribal district of Odisha, India
CONCLUSIONS: Community participation and coordination between different stakeholders have a significant impact on the successful implementation of the programme. It was suggested that there was a need for a sustainability approach to active participation, orientation and capacity building training among CHWs and community volunteers to successfully implement the programme.PMID:33907003 | DOI:10.4103/ijmr.IJMR_645_21
Source: The Indian Journal of Medical Research - April 28, 2021 Category: Biomedical Science Authors: Krushna Chandra Sahoo Sapna Negi Girish Chandra Dash Rakesh Kumar Sahoo Jaya Singh Kshatri Sheetal Panda Matrujyoti Pattanaik Goldi Badaik Sanghamitra Pati Debdutta Bhattacharya Source Type: research

Investigations of seasonal outbreaks of acute encephalitis syndrome due to < em > Orientia tsutsugamushi < /em > in Gorakhpur region, India: A One Health case study
Indian J Med Res. 2021 Mar;153(3):375-381. doi: 10.4103/ijmr.IJMR_625_21.ABSTRACTGorakhpur division consisting of Gorakhpur and neighboring districts Deoria, Kushinagar and Maharajganj in Uttar Pradesh, India, have been witnessing seasonal outbreaks of acute encephalitis syndrome (AES) among children for the last three decades. Investigations conducted during 2005 identified Japanese encephalitis (JE) virus as an aetiology of AES. With the introduction of JE vaccination and other control strategies, the incidence of JE in the region declined, however, outbreaks of acute febrile illness with neurological manifestations cont...
Source: The Indian Journal of Medical Research - April 28, 2021 Category: Biomedical Science Authors: Manoj V Murhekar Jeromie Wesley Vivian Thangaraj Candasamy Sadanandane Mahima Mittal Nivedita Gupta Winsley Rose Seema Sahay Rajni Kant Mohan D Gupte Source Type: research