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A case of febrile infection-related epilepsy syndrome (FIRES) in young adult: still a diagnostic and therapeutic challenge
We report a case of acute encephalopathy with refractory seizures after a febrile illness (FIRES) in a young adult with complete remission of symptoms as well as dramatic improvement of EEG abnormalities following intravenous immunoglobulin and proper antiepileptic medications. We con ducted an extensive workup including lumbar puncture, blood tests, EEG serial monitoring, MRI brain, total body CT scan, and PET brain with FDG to shed light on the etiology of the disease.
Source: Neurological Sciences - May 4, 2022 Category: Neurology Source Type: research

Thrombotic Thrombocytopenic Purpura Without Schistocytes: Beware of Misdiagnosis
A 43-year-old woman was admitted for acute unusual headache, vertigo, and left upper limb weakness. She had been complaining of asthenia for the past few weeks. Her medical history included uterine cervix cancer treated with conisation and 2 pregnancies without serious complications. No allergy or recent drug introduction was noted. After ruling out current pregnancy, magnetic resonance imaging (MRI) was immediately performed and showed recent ischemic strokes in multiple territories. Doppler ultrasound imaging showed no carotid or vertebral arteries lesion. Electrocardiogram showed no ST elevation or atrial fibrillation, ...
Source: Neurology Clinical Practice - October 11, 2021 Category: Neurology Authors: Decker, P., Moulinet, T., Revuz, S., Perez, P., Jaussaud, R. Tags: Autoimmune diseases, Hematologic, All Cerebrovascular disease/Stroke Case Source Type: research

Neurological Involvement in Primary Systemic Vasculitis
Conclusion Neurological involvement is a common complication of PSV (Table 1), and neurologists play an important role in the identification and diagnosis of PSV patients with otherwise unexplained neurological symptoms as their chief complaint. This article summarizes the neurological manifestations of PSV and hopes to improve neuroscientists' understanding of this broad range of diseases. TABLE 1 Table 1. Common CNS and PNS involvements of primary systemic vasculitis. Author Contributions SZ conceived the article and wrote the manuscript. DY and GT reviewed and edited the manuscript. All authors ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Combination of Dexmedetomidine and Ketamine for Magnetic Resonance Imaging Sedation
Conclusions: The efficacy of DEX–KET sedation was comparable to that of midazolam for MRI examination. DEX–KET was related to shorter scan time and lower occurrence of complications compared to midazolam. Introduction Neurocritically ill patients often require brain magnetic resonance imaging (MRI) in addition to conventional neurological evaluations. Brain MRI can reveal structural lesions with a high sensitivity due to its excellent spatial resolution and enhanced soft tissue contrast (1–3). To acquire MRI images, patients' cooperation is imperative. However, keeping patients with ...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Evidence of fatigue, disordered sleep and peripheral inflammation, but not increased brain TSPO expression, in seasonal allergy: A 11CPBR28 PET study
In conclusion, allergic subjects are indicated to respond to allergen exposure during pollen season with a clear pattern of behavioral disruption and peripheral inflammatory activation, but not with changes in brain TSPO levels. This underscores a need for development and use of more specific markers to understand brain consequences of peripheral inflammation that will be applicable in human subjects.
Source: Brain, Behavior, and Immunity - January 11, 2018 Category: Neurology Source Type: research

Evidence of fatigue, disordered sleep and peripheral inflammation, but not increased brain TSPO expression, in seasonal allergy: A (11)CPBR28 PET study.
In conclusion, allergic subjects are indicated to respond to allergen exposure during pollen season with a clear pattern of behavioral disruption and peripheral inflammatory activation, but not with changes in brain TSPO levels. This underscores a need fordevelopment and use of more specific markers to understand brain consequences of peripheral inflammation that will be applicable in human subjects. PMID: 29054675 [PubMed - as supplied by publisher]
Source: Brain, Behavior, and Immunity - October 17, 2017 Category: Neurology Authors: Tamm S, Cervenka S, Forsberg A, Estelius J, Grunewald J, Gyllfors P, Karshikoff B, Kosek E, Lampa J, Lensmar C, Strand V, Åkerstedt T, Halldin C, Ingvar M, Höglund CO, Lekander M Tags: Brain Behav Immun Source Type: research

Bilateral frontal cysts from a crista galli meningioma
A 73-year-old woman had progressive apathy, forgetfulness, and gait disturbance for 6 months. Neurologic examination showed inattentiveness, memory impairment, and broad-based gait. Noncontrast MRI was performed due to gadolinium allergy. MRI and contrast-enhanced CT scan revealed symmetric bilateral frontal cysts (figure 1A) and an anterior skull base nodule (figure 1, B and C). Surgery confirmed a meningioma arising from the crista galli (figure 2A). Her symptoms improved postoperatively and the cysts shrank significantly (figure 2B).
Source: Neurology - December 7, 2015 Category: Neurology Authors: Toda, H., Maekawa, H. Tags: CT, MRI, Primary brain tumor NEUROIMAGES Source Type: research

Digital Subtraction Angiography (DSA) Arch Run in Place of CT Vessel and Perfusion Imaging: Proof of Concept (P1.014)
CONCLUSIONS: In both cases, DSA arch runs generated adequate, rapid vessel imaging including demonstration of collaterals in place of CTA/CTP. This minimized delays in treatment, provided information key to predicting benefit and facilitated a shorter time to reperfusion. This is proof of concept, that DSA arch runs can be used in place of CTA/CTP in patients likely to require intra-arterial therapy.Disclosure: Dr. Campbell has nothing to disclose. Dr. Jadhav has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Campbell, D., Jadhav, A. Tags: Cerebrovascular Disease and Interventional Neurology I ePosters Source Type: research