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Total 214 results found since Jan 2013.

Sodium accumulation is associated with disability and progression in multiple sclerosis: a 23na mri study
Conclusions Significant increases in sodium were seen in lesions and normal appearing brain tissues in MS. Increased concentration of sodium in lesions, cortical grey matter, NAWM and basal ganglia in SPMS versus RRMS indicates greater neuroaxonal metabolic dysfunction and/or loss in the former group. MRI measurement of sodium concentration in vivo is likely to reflect clinically relevant neuroaxonal pathophysiology and may be a useful outcome measure in trials of putative neuroprotective treatments.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Paling, D., Solanky, B., Riemer, F., Tozer, D., Wheeler-Kingshott, C., Kapoor, R., Golay, X., Miller, D. Tags: Immunology (including allergy), Multiple sclerosis, Stroke, Radiology, Radiology (diagnostics) Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research

Neurological manifestations of influenza infection in adults and children: results of a national british surveillance study
Conclusion This paediatric and adult UK cohort identified a severity of influenza related neurological manifestation not reported previously. Cases were more common in children, particularly those with underlying neurological conditions. Encephalopathy syndromes such as ANE, AIEF, HSE and AHL were seen more frequently in children and were associated with a worse outcome. Acute movement disorders and Guillain–Barré syndrome were identified more commonly in adults. Influenza related encephalopathy may be more common in those with abnormal genetically determined host inflammatory responses, but the virus itself i...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Goenka, A., Michael, B., Ledger, E., Hart, I., Absoud, M., Chow, G., Lilleker, J., Lim, M., Lunn, M., Peake, D., Pysden, K., Roberts, M., Carrol, E., Avula, S., Solomon, T., Kneen, R. Tags: Immunology (including allergy), Meningitis, Infection (neurology), Radiology, Adult intensive care, Radiology (diagnostics) Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research

Most neurologists in scotland do not use the mcdonald 2010 criteria to diagnose multiple sclerosis
Conclusion Our data indicate significant variation in practice amongst Scottish neurologists regarding the diagnosis of MS. It seems that few are enthusiastic about applying the current diagnostic criteria after a single attack (CIS), even if the diagnostic criteria are met. Case mix, clinical expertise and experience may explain some of this variation, and given the lack of evidence for aggressive treatment of CIS, such diagnostic caution is perhaps justified. It would be of interest to repeat the audit UK wide, and internationally, and our prediction would be that some countries may embrace the criteria with more enthusi...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Lumley, R., Davenport, R., Williams, A. Tags: Immunology (including allergy), Multiple sclerosis, Radiology, Radiology (diagnostics) Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research

The role of brain mri in the diagnosis of neuromyelitis optica
Conclusion Application of the Oxford 2012 diagnostic criteria in a clinical setting resulted in an 85% specificity for differentiating NMO from RRMS, the most common differential diagnosis compared to only 67% for Barkhof's criteria. This data should be considered in the MRI assessment of patients in whom the diagnosis of NMO is being considered. In particular patients fulfilling Barkhof's criteria should also be assessed with the Oxford 2012 criteria to improve the interpretation of brain MR imaging and its diagnostic accuracy.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Luppe, S., Khirwadkar, H., Tomassini, V., Hourihan, M., Robertson, N. Tags: Immunology (including allergy), Brain stem / cerebellum, Cranial nerves, Multiple sclerosis, Neuroimaging, Ophthalmology, Radiology, Radiology (diagnostics) Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RC Source Type: research

A fatal case of 'primary' headache
We describe a case of a 33 year old caucasian male with a subacute history of headaches presenting to the medical team with pyrexia, confusion and hallucinations. He subsequently became disorientated, agitated and initially needed sedation and ventilation after becoming acutely hypoxic with autonomic instability. He was subsequently found to have dense, pre–geniculate blindness and generalised arreflexia. Magnetic resonance imaging demonstrated normal brain parenchyma but diffuse nodular thickening and enhancement of the basal leptomeninges in the brain and throughout the entire spinal cord. Lumbar puncture revealed ...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Dayanandan, R., Bindman, D., Chhetri, S. K., Jacob, J., Mathur, S., Mills, R. J. Tags: Immunology (including allergy), HIV/AIDS, Meningitis, Headache (including migraine), Infection (neurology), Neurooncology, Pain (neurology), CNS cancer, Ophthalmology, Radiology, Surgical diagnostic tests, Radiology (diagnostics) Association of British Source Type: research

Brain atrophy and lesion load predict long term disability in multiple sclerosis
Conclusions This large multicentre study points to the complementary predictive value of atrophy and lesion volumes for predicting long term disability in MS.
Source: Journal of Neurology, Neurosurgery and Psychiatry - September 2, 2013 Category: Neurosurgery Authors: Popescu, V., Agosta, F., Hulst, H. E., Sluimer, I. C., Knol, D. L., Sormani, M. P., Enzinger, C., Ropele, S., Alonso, J., Sastre-Garriga, J., Rovira, A., Montalban, X., Bodini, B., Ciccarelli, O., Khaleeli, Z., Chard, D. T., Matthews, L., Palace, J., Gior Tags: Immunology (including allergy), Multiple sclerosis, Radiology, Radiology (diagnostics) Source Type: research

Olfactory bulb volume changes in patients with sinonasal polyposis: a magnetic resonance imaging study.
PMID: 24119610 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - September 1, 2013 Category: ENT & OMF Authors: Amedee RG Tags: Am J Rhinol Allergy Source Type: research

Estimation of sensitivity and specificity of brain magnetic resonance imaging and single photon emission computed tomography in the diagnosis of olfactory dysfunction after head traumas.
CONCLUSION: According to our study, both brain MRI and SPECT have high sensitivity and specificity in the diagnosis of traumatic anosmia, although brain SPECT is slightly superior to MRI. If the two techniques are applied together, the accuracy will be increased. PMID: 24119604 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - September 1, 2013 Category: ENT & OMF Authors: Atighechi S, Zolfaghari A, Baradaranfar M, Dadgarnia M Tags: Am J Rhinol Allergy Source Type: research

The ideal puncture approach for PCNL: Fluoroscopy, ultrasound or endoscopy?
Bannakij LojanapiwatIndian Journal of Urology 2013 29(3):208-213Percutaneous renal access is a common procedure in urologic practice. The main indications are drainage of an obstructed and hydronephrotic kidney and antegrade renal access prior to percutaneous renal surgeries such as percutaneous nephrolithotomy (PCNL) and percutaneous endopyelotomy (EP). The contraindications for this technique are patients with history of allergy to topical or local anesthesia and patients with coagulopathy. The creation of a percutaneous tract into the renal collecting system is one of the important steps for percutaneous renal access. T...
Source: Indian Journal of Urology - August 29, 2013 Category: Urology & Nephrology Authors: Bannakij Lojanapiwat Source Type: research

New insight into the assessment of asthma using xenon ventilation computed tomography.
CONCLUSION: The results of this study suggest that xenon ventilation CT can be used as a new method to assess ventilation abnormalities in asthma, and these ventilation abnormalities can be used as novel parameters that reflect the status of asthma control and symptom severity. PMID: 23886225 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - July 28, 2013 Category: Allergy & Immunology Authors: Jung JW, Kwon JW, Kim TW, Lee SH, Kim KM, Kang HR, Park HW, Lee CH, Goo JM, Min KU, Cho SH Tags: Ann Allergy Asthma Immunol Source Type: research

Brain injury due to anaphylactic shock: broadening manifestations of Kounis syndrome
This article is protected by copyright. All rights reserved.
Source: International Endodontic Journal - June 20, 2013 Category: Dentistry Authors: G. D. Soufras, G. N. Kounis, N. G. Kounis Tags: Mini Review Source Type: research

Severe drug‐induced anaphylaxis: analysis of 333 cases recorded by the Allergy Vigilance Network from 2002 to 2010
ConclusionsThree hundred and thirty‐three case reports provided data on drugs involved in severe anaphylaxis. The efficacy of skin tests and poor use of laboratory tests are underlined. Further progress may depend on OCs.
Source: Allergy - June 6, 2013 Category: Allergy & Immunology Authors: J.‐M. Renaudin, E. Beaudouin, C. Ponvert, P. Demoly, D.‐A. Moneret‐Vautrin Tags: Original Article Source Type: research

Does the site of magnetic resonance imaging abnormalities match the site of recent-onset inflammatory back pain? The DESIR cohort
Conclusions The site of pain (thoracic spine, lumbar spine or buttock(s)) is associated with MRI inflammation at the same site in patients with recent IBP.
Source: Annals of the Rheumatic Diseases - May 10, 2013 Category: Rheumatology Authors: Blachier, M., Coutanceau, B., Dougados, M., Saraux, A., Bastuji-Garin, S., Ferkal, S., Le Corvoisier, P., Farrenq, V., Poulain, C., Ghaleh, B., Canoui-Poitrine, F., Claudepierre, P. Tags: Immunology (including allergy), Pain (neurology), Inflammation, Radiology, Clinical diagnostic tests, Radiology (diagnostics), Epidemiology Clinical and epidemiological research Source Type: research

Chapter 10: Sinonasal malignancies.
This article reviews the classification of malignant tumors of the paranasal sinuses, their clinical presentation, relevant diagnostic investigations, and the principals of therapy and management. PMID: 23711038 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - May 1, 2013 Category: ENT & OMF Authors: Harvey RJ, Dalgorf DM Tags: Am J Rhinol Allergy Source Type: research

Alliaceous Migraines
Conclusion.—This is the first report of migraines with aura triggered by more than one alliaceous compound in the same individual. Possible mechanisms include odor induced, emotional change, vasomotor instability, trigeminal‐induced neurogenic inflammation, and allergic response. In alliaceous and odor‐induced migraines, a trial of counter stimulation and nose plugs is warranted.
Source: Headache: The Journal of Head and Face Pain - April 1, 2013 Category: Neurology Authors: Alexander P. Roussos, Alan R. Hirsch Tags: Brief Communication Source Type: research