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Total 1324 results found since Jan 2013.

Granulocyte Colony-stimulating Factor-associated Aortitis on Gallium Scintigraphy
Intern Med. 2023 Mar 22. doi: 10.2169/internalmedicine.1453-22. Online ahead of print.ABSTRACTAortitis is a rare adverse event associated with granulocyte colony-stimulating factor (G-CSF). Contrast-enhanced computed tomography (CECT) is widely used to diagnose G-CSF-associated aortitis. However, the usefulness of gallium scintigraphy for the diagnosis of G-CSF-associated aortitis is unknown. We herein report a set of pre- and post-treatment gallium scintigrams of a patient with G-CSF-associated aortitis. During the diagnosis, gallium scintigraphy revealed hot spots on the arterial walls that appeared inflamed on CECT. Bot...
Source: Internal Medicine - March 22, 2023 Category: Internal Medicine Authors: Haruka Ozaki Kohji Takemura Rika Kizawa Takeshi Yamaguchi Chinatsu Komiyama Masato Tachi Hirotaka Maruno Yuko Tanabe Koichi Suyama Yuji Miura Source Type: research

Calprotectin in Chronic Rhinosinusitis Eosinophil Extracellular Traps
Conclusions: Calprotectin, known to be secreted by neutrophils, in CRS was also expressed in eosinophils. In addition, calprotectin, which functions as an antimicrobial peptide, may play an important role in the innate immune response based on its EETs involvement. Therefore, calprotectin expression could reflect as a disease severity biomarker for CRS.This article is protected by copyright. All rights reserved
Source: International Forum of Allergy and Rhinology - March 18, 2023 Category: Allergy & Immunology Authors: Sang Hyeon Ahn, Kyu Ha Shin, Jun Taek Oh, Sang Chul Park, Min ‐Seok Rha, Soo In Kim BS, Hyung‐Ju Cho, Joo‐Heon Yoon, Chang‐Hoon Kim Tags: ORIGINAL ARTICLE Source Type: research

Temperature ‐controlled radiofrequency device treatment of septal swell bodies for nasal airway obstruction: An open‐label, single arm multicenter study
Conclusions: This study demonstrates that temperature-controlled radiofrequency treatment of SSB hypertrophy is well-tolerated and effective at reducing both SSB size and symptoms of NAO at 3 months post-treatment.This article is protected by copyright. All rights reserved
Source: International Forum of Allergy and Rhinology - March 13, 2023 Category: Allergy & Immunology Authors: Jordan Pritikin, Stacey Silvers, Jeffrey Rosenbloom, Bryan Davis, Anthony Del Signore, Ahmad R Sedaghat, Bobby A Tajudeen, Isaac Schmale, Jack Lyons, Jacquelynne Corey, Rakesh Chandra Tags: ORIGINAL ARTICLE Source Type: research

Occupational Interstitial Lung Diseases
Occupational exposures are directly causal or partially contributory to the development of interstitial lung diseases. A detailed occupational history, relevant high-resolution computed tomography findings, and where relevant additional histopathology, are required to make a diagnosis. Treatment options are limited, and further exposure avoidance is likely to reduce disease progression.
Source: Immunology and Allergy Clinics of North America - March 3, 2023 Category: Allergy & Immunology Authors: Hayley Barnes, Ian Glaspole Source Type: research

Reply
We read with enthusiasm the correspondence by Nomura et  al1 in reference to our original article “Refractory neutrophilic asthma and ciliary genes.”2 In their comment, Nomura et al identified a single-nucleotide polymorphism (SNP), rs2523870, that correlated with findings on chest imaging, specifically the “tree-in-bud” pattern. This computed tomography finding is often consistent with a nonspecific bronchiolitis pattern and may also be seen in patients with asthma who exhibit increased mucus burden, as was seen in our patient population.
Source: Journal of Allergy and Clinical Immunology - March 3, 2023 Category: Allergy & Immunology Authors: Vamsi P. Guntur, Camille M. Moore, Laurie A. Manka Tags: Correspondence Source Type: research

Importance of mucus burden and mucociliary impairment in asthma
This article showed that the dysregulation and downregulation of ciliary genes may contribute to the development of refractory asthma (RA), particularly its subgroup cilium-deficient RA. The cilium-deficient RA showed both type 2 a nd non–type 2 inflammation and a high risk of subclinical infection with findings of “mucus,” “bronchiectasis/bronchial dilatation,” or “tree-in-bud” on chest computed tomography (CT).
Source: Journal of Allergy and Clinical Immunology - March 3, 2023 Category: Allergy & Immunology Authors: Natsuko Nomura, Hisako Matsumoto, Hironobu Sunadome, Tsuyoshi Oguma, Toyohiro Hirai Tags: Correspondence Source Type: research

Radiographic predictors of occult intracranial involvement in olfactory neuroblastoma patients
Conclusions: Both CT and MRI had reasonably good NPV for involvement of dura and olfactory bulb. Higher Hyam's grade was associated with dural involvement. Patients with low-grade tumors not involving the skull base may be suitable for avoiding skull base resection, however further investigation is warranted.This article is protected by copyright. All rights reserved
Source: International Forum of Allergy and Rhinology - February 26, 2023 Category: Allergy & Immunology Authors: Mathew Geltzeiler, Garret W. Choby, Keven Seung Yong Ji, Jess C. Mace, Joao Paulo Almeida, John Almeida, Pierre ‐Olivier Champagne, Erik Chan, Jeremy N Ciporen, Mark B. Chaskes, Sarah Cornell, Veronica Drozdowski, Juan Fernandez‐Miranda, Tags: ORIGINAL ARTICLE Source Type: research

Doxycycline Improves Quality of Life and Anosmia in Chronic Rhinosinusitis With Nasal Polyposis: A Randomized Controlled Trial
CONCLUSION: Doxycycline improves the quality of life in patients with CRSwNP. It also has temporarily beneficial effects in improving the sense of smell. The levels of eosinophil in the blood and nasal secretions do not affect the response to treatment. Hence, doxycycline can be used in both eosinophilic and non-eosinophilic nasal polyps.This study was registered at Iranian Registry of Clinical Trials. https://www.irct.ir/ IRCTID: IRCT20210403050817N1.PMID:36740870 | DOI:10.1177/19458924231154066
Source: American Journal of Rhinology and Allergy - February 6, 2023 Category: ENT & OMF Authors: Mohammad Nabavi Saba Arshi Mohammad Hassan Bemanian Morteza Fallahpour Sima Shokri Sofia Sabouri Fatima Moosavian Javad Nazari Vahid Bakrani Fatemeh Atashrazm Source Type: research