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Vaccination: Influenza Vaccine

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Total 364 results found since Jan 2013.

Allergic reactions to vaccines
Anaphylactic reactions to vaccines are rare but do occur, and have been reported for nearly every vaccine. And while the reaction rate per each dose of vaccine is low, this is a common clinical question due in large part to the enormous numbers of vaccines administered. Reactions are most often due to vaccine constituents rather than the microbial components of the vaccine, but in many instances, the specific ingredient triggering the reaction cannot be definitively identified. Evaluation of patients with suspected vaccine reactions should begin by determining whether the symptoms and timing of the reaction were consistent...
Source: Pediatric Allergy and Immunology - July 31, 2013 Category: Allergy & Immunology Authors: Robert A. Wood Tags: Review Article Source Type: research

Republished: Novel insights into immune and inflammatory responses to respiratory viruses
Viral lower respiratory tract infection (LRTI) can lead to severe disease at all ages, but with the exception of influenza vaccination, prevention is not available for most respiratory viruses, hence, effective, disease-limiting therapy is urgently required. To enable the development of novel effective therapeutic approaches, we need to improve understanding of the pathological mechanisms of viral LRTI. Here, we will discuss recently gained new insight into early, innate immune and inflammatory responses to respiratory viruses by airway epithelial cells and mucosal immune cells. Following virus recognition, these cells gen...
Source: Postgraduate Medical Journal - August 16, 2013 Category: Journals (General) Authors: Schwarze, J., Mackenzie, K. J. Tags: Immunology (including allergy), Drugs: infectious diseases Republished basic science for the clinician Source Type: research

Increased city-level influenza mortality and state-level influenza severity is associated with greater functional decline among nursing home residents
Commentary on: Gozalo PL, Pop-Vicas A, Feng Z, et al.. Effect of influenza on functional decline. J Am Geriatr Soc 2012;60:1260–7. Implications for practice and research Prevention of exposure to influenza among long-stay nursing home residents has the potential to prevent significant morbidity, including functional decline. Nursing home quality measures may need to be adjusted seasonally or for regional influenza severity. Future research is needed to confirm these associations on an individual level and to determine if preventive measures, such as resident and staff vaccination and hand hygiene, can prevent functio...
Source: Evidence-Based Nursing - September 7, 2013 Category: Nursing Authors: Hardy, S. Tags: Immunology (including allergy), Drugs: infectious diseases, Influenza, TB and other respiratory infections, Vaccination / immunisation, Pain (neurology), Drugs: psychiatry, Psychotic disorders (incl schizophrenia), Dermatology Care of older people Source Type: research

NIH Begins Testing H7N9 Avian Influenza Vaccine Candidate
Source: National Institute of Allergy and Infectious Diseases - Related MedlinePlus Page: Bird Flu
Source: MedlinePlus Health News - September 19, 2013 Category: Consumer Health News Source Type: news

University of Maryland researchers studying vaccine to prevent potential bird flu pandemic
(University of Maryland Medical Center) Scientists at the University of Maryland School of Medicine's Center for Vaccine Development are part of nationwide vaccine research aimed at protecting adults from a new and virulent strain of avian influenza virus. The virus, called H7N9 influenza virus, emerged in China last spring. The study, sponsored by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, will help prepare for the possibility of a global pandemic.
Source: EurekAlert! - Social and Behavioral Science - September 18, 2013 Category: Global & Universal Source Type: news

'Reassuring' findings released in national study of influenza vaccine safety in pregnancy
(Boston University Medical Center) Researchers from Boston University's Slone Epidemiology Center and UC San Diego, in collaboration with the American Academy of Allergy Asthma and Immunology, have found 'reassuring' evidence of the H1N1 influenza vaccine's safety during pregnancy.
Source: EurekAlert! - Medicine and Health - September 23, 2013 Category: Global & Universal Source Type: news

Reassuring findings for mothers who have influenza vaccine while pregnant
(University of California - San Diego) Researchers from the University of California, San Diego School of Medicine and Boston University, in collaboration with the American Academy of Allergy Asthma and Immunology, have found evidence of the H1N1 influenza vaccine's safety during pregnancy. The national study, which was launched shortly after the H1N1 influenza outbreak of 2009, is summarized in two companion papers published online on Sept. 19 in the journal Vaccine.
Source: EurekAlert! - Medicine and Health - September 23, 2013 Category: Global & Universal Source Type: news

Neurological manifestations of influenza infection in adults and children: results of a national british surveillance study
Conclusion This paediatric and adult UK cohort identified a severity of influenza related neurological manifestation not reported previously. Cases were more common in children, particularly those with underlying neurological conditions. Encephalopathy syndromes such as ANE, AIEF, HSE and AHL were seen more frequently in children and were associated with a worse outcome. Acute movement disorders and Guillain–Barré syndrome were identified more commonly in adults. Influenza related encephalopathy may be more common in those with abnormal genetically determined host inflammatory responses, but the virus itself i...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Goenka, A., Michael, B., Ledger, E., Hart, I., Absoud, M., Chow, G., Lilleker, J., Lim, M., Lunn, M., Peake, D., Pysden, K., Roberts, M., Carrol, E., Avula, S., Solomon, T., Kneen, R. Tags: Immunology (including allergy), Meningitis, Infection (neurology), Radiology, Adult intensive care, Radiology (diagnostics) Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research

Should all children be immunised against influenza?
Introduction—flu vaccines in children and indirect effects Influenza is an important cause of morbidity and mortality, especially in combination with secondary bacterial infections.1–3 Annual influenza vaccination is recommended for everyone at risk by the WHO.4 In recent years, a number of countries have recommended influenza vaccination for all children older than 6 months although the uptake has been variable. The effectiveness of inactivated influenza vaccines in children has been questioned.5 Numerous studies have been published on the subject but outcome measures used vary with some studies using inf...
Source: Archives of Disease in Childhood - October 11, 2013 Category: Pediatrics Authors: Thors, V., Smith, C., Finn, A. Tags: Epidemiologic studies, Vaccination programs, Immunology (including allergy), Drugs: infectious diseases, Influenza, Pneumonia (infectious disease), TB and other respiratory infections, Vaccination / immunisation, Child health, Pneumonia (respiratory medic Source Type: research

Testosterone-regulated genes may affect vaccine-induced immunity
A new study has identified a link between certain genes affected by testosterone and antibody responses to an influenza vaccine. The findings, published in Proceedings of the National Academy of Sciences, suggest that testosterone levels may partially explain why men often have weaker responses to vaccines than women. The study, led by researchers at Stanford University, was supported in part by the National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health.
Source: Health News from Medical News Today - January 2, 2014 Category: Consumer Health News Tags: Immune System / Vaccines Source Type: news

Premature immune senescence during HIV-1 vertical infection relates with response to influenza vaccination
Intrinsic defects in B cells have been described in chronically HIV-1-positive individuals; these defects are only partially reversed following antiretroviral therapy (ART) and virologic suppression. Increasing evidence in the literature points to a potential role of chronic immune activation in the premature aging of the immune system in HIV-1 infection. In particular, impaired activation-induced deaminase transcription relating to the A(H1N1)pdm09 influenza vaccination has been reported for both healthy elderly and HIV-1-positive individuals. Altered B-cell subpopulations resembling the CD27-IgD-double-negative (DN) B ce...
Source: Journal of Allergy and Clinical Immunology - December 2, 2013 Category: Allergy & Immunology Authors: Alberto Cagigi, Stefano Rinaldi, Angela Di Martino, Emma Concetta Manno, Paola Zangari, Angela Aquilani, Nicola Cotugno, Luciana Nicolosi, Alberto Villani, Stefania Bernardi, Isabella Donatelli, Savita Pahwa, Paolo Rossi, Paolo Palma Tags: Letters to the Editor Source Type: research

Influenza vaccination in asthmatic patients
Credit can now be obtained, free for a limited time, by reading the review articles in this issue. Please note the instructions listed below:
Source: Journal of Allergy and Clinical Immunology - March 31, 2014 Category: Allergy & Immunology Authors: Matthew J. Greenhawt Tags: Maintenance of Certification clinical management series Source Type: research

UTMB awarded $4.4M to develop universal flu vaccine
(University of Texas Medical Branch at Galveston) UTMB researchers are working to create a universal flu vaccine -- one that could eliminate the need for an annual flu shot. Thanks to a $4.4 million grant from the National Institute of Allergy and Infectious Diseases, UTMB researchers and biotechnology company Etubics Corporation plan to construct, produce and test a vaccine containing various antigens of the A and B strains of influenza.
Source: EurekAlert! - Infectious and Emerging Diseases - May 7, 2014 Category: Infectious Diseases Source Type: news

UTMB awarded $4.4 million to develop universal flu vaccine
(University of Texas Medical Branch at Galveston) UTMB researchers are working to create a universal flu vaccine -- one that could eliminate the need for an annual flu shot. Thanks to a $4.4 million grant from the National Institute of Allergy and Infectious Diseases, UTMB researchers and biotechnology company Etubics Corporation plan to construct, produce and test a vaccine containing various antigens of the A and B strains of influenza.
Source: EurekAlert! - Infectious and Emerging Diseases - May 7, 2014 Category: Infectious Diseases Source Type: news

Pandemic A/H1N1 2009 influenza vaccination, preceding infections and clinical findings in UK children with Guillain-Barre syndrome
Conclusions The outcome for childhood GBS and FS after 6 months was better than reported in adults. Most UK GBS and FS cases had infections in the preceding 3 months. When considering the children living in England, there was no significantly increased risk of GBS after pandemic A/H1N1 2009 influenza vaccination or 2010/2011 seasonal influenza vaccination.
Source: Archives of Disease in Childhood - May 15, 2014 Category: Pediatrics Authors: Verity, C., Stellitano, L., Winstone, A. M., Stowe, J., Andrews, N., Miller, E. Tags: Epidemiologic studies, Immunology (including allergy), Drugs: infectious diseases, Bird flu, Influenza, TB and other respiratory infections, Vaccination / immunisation, Child health Original article Source Type: research