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Key stakeholder perspectives on challenges and opportunities for rural HPV vaccination in North and South Carolina
The objective of this study was to identify factors at the individual, provider, and systems levels that serve as challenges or opportunities for increasing adolescent vaccination-including Human Papillomavirus (HPV) vaccination-in rural communities in the southern United States (US). As part of a broader study to increase HPV vaccine uptake in the southern US, we conducted in-depth interviews with vaccination stakeholders representing public health and education agencies in North Carolina (NC) and South Carolina (SC). Fourteen key stakeholders were recruited using purposive sampling to obtain insights into challenges and ...
Source: Cancer Control - April 19, 2022 Category: Cancer & Oncology Authors: Laura J Fish Sayward E Harrison Jodi-Ann McDonald Valerie Yelverton Charnetta Williams Emmanuel B Walter Lavanya Vasudevan Source Type: research

Predictors of HPV vaccination in the southern US: A survey of caregivers from 13 states
CONCLUSIONS: Our findings suggest missed opportunities for HPV vaccination in the southern US and support strengthening provider recommendation for on-time initiation of HPV vaccination among adolescents. Other strategies to increase HPV vaccinations may include encouraging co-administration with other adolescent vaccines, increasing vaccine access, and promoting vaccinations for home/online-school students.PMID:34742592 | DOI:10.1016/j.vaccine.2021.10.036
Source: Vaccine - November 7, 2021 Category: Allergy & Immunology Authors: Lavanya Vasudevan Jan Ostermann Yunfei Wang Sayward E Harrison Valerie Yelverton Jodi-Ann McDonald Laura J Fish Charnetta Williams Emmanuel B Walter Source Type: research

Differentially expressed genes involved in immune pathways from yellowhead catfish (Tachysurus fulvidraco) after poly (I:C) challenge
In conclusion, our findings provide novel insight into the immune responses of T. fulvidraco and suggest that poly (I:C) may represent a promising adjuvant of fish vaccines.PMID:33932411 | DOI:10.1016/j.ijbiomac.2021.04.167
Source: International Journal of Biological Macromolecules - May 1, 2021 Category: Biochemistry Authors: Qiu-Ning Liu Ying-Yu Tang Meng-Jiao Zhou Sha Luo Yue-Tian Li Gang Wang Dai-Zhen Zhang Hui Yang Bo-Ping Tang Wen-Fei He Source Type: research

Inside the Global Quest to Trace the Origins of COVID-19 —and Predict Where It Will Go Next
It wasn’t greed, or curiosity, that made Li Rusheng grab his shotgun and enter Shitou Cave. It was about survival. During Mao-era collectivization of the early 1970s, food was so scarce in the emerald valleys of southwestern China’s Yunnan province that farmers like Li could expect to eat meat only once a year–if they were lucky. So, craving protein, Li and his friends would sneak into the cave to hunt the creatures they could hear squeaking and fluttering inside: bats. Li would creep into the gloom and fire blindly at the vaulted ceiling, picking up any quarry that fell to the ground, while his companion...
Source: TIME: Health - July 23, 2020 Category: Consumer Health News Authors: Charlie Campbell/ Yuxi, Yunnan and Alice Park Tags: Uncategorized COVID-19 feature Magazine Source Type: news

From “Serum Sickness” to “Xenosialitis”: Past, Present, and Future Significance of the Non-human Sialic Acid Neu5Gc
Conclusions and Perspectives In this review, we have discussed important milestones from the early description of “Serum-sickness” as being due to antibodies directed against Neu5Gc epitopes all the way to the present-day therapeutic implications of these antibodies in cancer therapy. Some of these milestones have been represented in a concise timeline (Figure 6). While the “Xenosialitis” hypothesis is well-supported in the human-like mouse models, it has yet to be conclusively proven in humans. It remains to be seen if “Xenosialitis” plays a role in other uniquely-human dis...
Source: Frontiers in Immunology - April 16, 2019 Category: Allergy & Immunology Source Type: research