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Nutrition: Calcium

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Different impact of NNRTI and PI-including HAART on bone mineral density loss in HIV-infected patients.
CONCLUSIONS: The study showed that in HIV patients on HAART BMD decrease, even osteoporosis, can be present persisting over time, particularly in PI in respect of NNRTI treated patients. The pathogenesis is probably multifactorial, the different antiviral drugs seeming to differently affect bone metabolism. Alendronate/Vitamin D/Calcium therapy can be useful to slow down bone mass loss and also improve osteoporosis/osteopenia conditions, thus, reducing fracture risk also continuing HAART. PMID: 26698255 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - December 25, 2015 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research

Identification and validation of novel prognostic markers in Renal Cell Carcinoma.
Authors: Rabjerg M Abstract Kidney cancer (Renal Cell Carcinoma (RCC)) is one of the most deadly malignancies due to frequent late diagnosis and poor treatment options. Histologically, RCC embraces a wide variety of different subtypes with the clear cell variant (ccRCC) being the most common, accounting for 75-90% of all RCCs. At present, the surveillance protocols for follow-up of RCC patients after radical nephrectomy are based on the American Joint Committee on Cancers (AJCC) pathological tumor-node-metastasis (TNM) classification system. Other comprehensive staging modalities have emerged and have been implemen...
Source: Danish Medical Journal - October 6, 2017 Category: General Medicine Tags: Dan Med J Source Type: research

Abiomed puts $15m into Shockwave
Abiomed (NSDQ:ABMD) plans to invest $15 million in Shockwave Medical and collaborate on a training and education program in the U.S. and Germany, according to a newly-inked deal between the two companies. Shockwave’s intravascular lithotripsy technology uses sonic pressure waves to crack vascular calcium in the vessel wall, allowing arteries to expand under low pressure. The company said its catheter is often used in patients with heavily calcified Iliac arteries in order to prepare for the delivery of devices with catheters, like transcatheter heart valves and Abiomed’s Impella heart pump. “While we are...
Source: Mass Device - December 11, 2018 Category: Medical Devices Authors: Sarah Faulkner Tags: Cardiovascular Featured Funding Roundup Wall Street Beat Abiomed Shockwave Medical Source Type: news

Medical expulsive treatment for ureteral stones.
CONCLUSIONS: Higher quality clinical trials are needed to reliably advice MET. With the current evidence, it appears that MET can improve the expulsion of distal ureteral lithiasis ≥ 5 mm and ≤ 10 mm, even though we have not found differences between the drugs that are available for MET. PMID: 33459624 [PubMed - in process]
Source: Archivos Espanoles de Urologia - January 21, 2021 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Polyuria, Polydipsia and Possible Diabetes Insipidus?
Discussion The body is smart. It has mechanisms for maintaining balances within the body in a closely controlled manner but allows for a variety of states. This is very true for fluid balance in the body which is highly controlled between almost all of the major body organ systems. When fluid is low, the sensor sends signals for us to drink, and conserves fluid until we can. When the fluid is high, the kidneys excrete the excess and sends signals not to drink. Usually it works very well. While there are many pathological states that can cause polyuria and/or polydipsia, the most common reason is excessive fluid intake beca...
Source: PediatricEducation.org - March 7, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Medical Management of Primary Hyperparathyroidism: Proceedings of the Fourth International Workshop on the Management of Asymptomatic Primary Hyperparathyroidism.
Conclusions: The recommended calcium intake in patients with PHPT should follow guidelines established for all individuals. It is not recommended to limit calcium intake in patients with PHPT who do not undergo surgery. Patients with low serum 25-hydroxyvitamin D should be repleted with doses of vitamin D aiming to bring serum 25-hydroxyvitamin D levels to ≥ 50 nmol/L (20 ng/mL) at a minimum, but a goal of ≥75 nmol/L (30 ng/mL) also is reasonable. Pharmacological approaches are available and should be reserved for those patients in whom it is desirable to lower the serum calcium, increase BMD, or both. For the control ...
Source: The Journal of Clinical Endocrinology and Metabolism - August 27, 2014 Category: Endocrinology Authors: Marcocci C, Bollerslev J, Khan AA, Shoback DM Tags: J Clin Endocrinol Metab Source Type: research

Medical expulsive therapy in urolithiasis: A mixed treatment comparison network meta-analysis of randomized controlled clinical trials.
CONCLUSION: To conclude, we observed a statistically significant increase in the expulsion rate and shorter expulsion time with alpha blockers, PDEI and combined alpha blockers with corticosteroids. Of these interventions, alpha blockers have the high probability of being the 'best'. PMID: 28756724 [PubMed - as supplied by publisher]
Source: Expert Opinion on Pharmacotherapy - August 2, 2017 Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research

The Effect of Education Intervention on Osteoporotic Fracture and Bone Mineral Density in Elderly Women With Osteoporosis: A Randomized Controlled Trial
CONCLUSIONS: The personalized education intervention by endocrinologists can significantly increase the BMD of the greater trochanter of the femur and reduce pain scores in elderly women with osteoporosis, suggesting that this education intervention may serve as an important addition to standard anti-osteoporosis treatment.PMID:34936992
Source: Alternative Therapies in Health and Medicine - December 22, 2021 Category: Complementary Medicine Authors: Min Chen Yiyi Zhang Lei Zhang Ling Wang Qin Guo Hui Zhou Wei Wang Yi He Shan Xia Liyang Shao Source Type: research