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Infectious Disease: Influenza

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Total 693 results found since Jan 2013.

Host immune responses to influenza infection and vaccines: Lessons learned for all viral pandemic challenges.
PMID: 32564928 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - June 24, 2020 Category: Allergy & Immunology Authors: Engler RJM, Nelson MR Tags: Ann Allergy Asthma Immunol Source Type: research

Evaluating the Immune Response of Recombinant H1N1 Hemagglutinin with MF59 Adjuvant in Animal Model as a Novel Alternative to the Influenza Vaccine.
This study examines the potential function of formulated H1N1 hemagglutinin with MF59 adjuvant against A/PR/8/34 (H1N1). To this end, a recombinant hemagglutinin (rHA) gene of influenza A virus was designed and expressed in SF9 cell by the Baculovirus expression system. Four groups of mice were immunized by rHA in combination with MF59, Alum adjuvant, and virus split only. The immunized mice subsequently used for the humoral immune assay and the results compared with untreated mice (negative group). Besides, both treated and control mice groups were challenged with mouse-adapted influenza virus A/PR/8/34(H1N1) through the ...
Source: Iranian Journal of Allergy, Asthma and Immunology - October 18, 2020 Category: Allergy & Immunology Authors: Rashedi N, Taghizadeh M, Mohamadynejad P, Mahdavi M, Jalalirad R Tags: Iran J Allergy Asthma Immunol Source Type: research

Impact of Age and Region on Immune Responses to Allergy Immunotherapy
Allergy immunotherapy (AIT) can prevent allergic disease by modifying the adaptive immune system, similar to anti-pathogen vaccines, supporting the concept of AIT as an “allergy vaccination”. Some vaccines, e.g. influenza, pneumococcal pneumoniae, are administered globally with the same dose for all age groups. The aim of this study was to determine if sublingual immunotherapy (SLIT) across regions and age groups induce similar immunologic changes in IgE and Ig G4 with the goal of using the same dose and formulation worldwide.
Source: Journal of Allergy and Clinical Immunology - February 1, 2021 Category: Allergy & Immunology Authors: Josephine Nolte Peterlin, Vibeke Backer, Thomas Stranzl, Veronica Hulstroem, Peter Sejer Andersen, Hendrik Nolte Source Type: research

A Quality Improvement Initiative to Improve Resident- Physician Practices Regarding Flu Vaccine Administration in Individuals with Egg Allergy
Individuals with any severity of egg allergy, including anaphylaxis, should receive the influenza vaccine annually per CDC guidelines. This recommendation has evolved over the past ten years. We performed a quality improvement initiative to assess and improve resident physician practices regarding flu vaccine administration in egg allergic individuals.
Source: Journal of Allergy and Clinical Immunology - February 1, 2021 Category: Allergy & Immunology Authors: Aishwarya Navalpakam, Shweta Saini, Chi- Lan Tran, Jenny Huang, Divya Seth, Pavadee Poowuttikul Source Type: research

A083 maximizing influenza vaccine rates in allergy shot patients
Immunizations are a fundamental part of healthcare. Immunization status should be screened at each clinic visit. Subcutaneous immunotherapy (SCIT) and biologic patients visit allergy clinics regularly for injections and provide frequent opportunities to assess immunization status, specifically the annual influenza vaccine. Studies reveal patients are more likely to receive vaccinations when recommended by a medical provider. Annual influenza vaccine rates were 48.4% during the 2019-20 influenza season in the  US.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2021 Category: Allergy & Immunology Authors: J. Gubin, M. Tankersley Source Type: research

Influenza vaccination patterns in an Allergy specialty clinic during COVID-19
We sought to determine the effect of the SARS-COV-2 pandemic on seasonal influenza vaccine patterns in a tertiary care, pediatric Allergy clinic.
Source: Journal of Allergy and Clinical Immunology - February 1, 2022 Category: Allergy & Immunology Authors: Jackson Massanelli, Robbie Pesek, Amika Sood, Kim Cobb, Stacie Jones Source Type: research

Why Allergy Seasons Are Getting Worse
If you’ve been itchy, congested, and sneezy for months, you’re not alone. This year’s spring allergy season started early, broke pollen-count records in some parts of the country, and is still going strong in many areas. Unfortunately, this year is unlikely to be a fluke. While pollen counts vary from year to year, recent trends suggest allergy seasons are, in general, getting longer and worse, says Dr. Kristine Vanijcharoenkarn, an assistant professor at Emory University School of Medicine who specializes in allergies and immunology. Patients started filling her office early this year, around the beginni...
Source: TIME: Health - May 9, 2023 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Environment healthscienceclimate Source Type: news

What Are Risk Factors for Latex Allergy?
Discussion Latex comes from the Hevea brasiliensis plants. There are multiple potentially allergenic polypeptides within the plant’s fluid called Heb b 1-13. True sensitizers are Heb b 1, 5 and 6. Heb b 8 and 12 are cross-reacting proteins. The type of the latex product and how it is prepared makes a difference in exposure to the latex allergens. Certain extruded latex products such as catheters and rubber stoppers have higher concentrations of true sensitizer allergens. Products made from molds such as gloves have higher concentrations of potential allergens than latex made in sheets such as such as dental dams. Use...
Source: PediatricEducation.org - February 1, 2016 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Hong Kong Institute of Allergy and Hong Kong Society for Paediatric Immunology Allergy & Infectious Diseases joint consensus statement 2018 on vaccination in egg-allergic patients.
Hong Kong Institute of Allergy and Hong Kong Society for Paediatric Immunology Allergy & Infectious Diseases joint consensus statement 2018 on vaccination in egg-allergic patients. Hong Kong Med J. 2018 Oct;24(5):527-531 Authors: Chua GT, Li PH, Ho MH, Lai E, Ngai V, Yau FY, Kwan MY, Leung TF, Lee TH Abstract Vaccination of egg-allergic individuals has been a historical concern, particularly for influenza and measles-mumps-rubella-varicella vaccines that are developed in chicken egg embryos or chicken cell fibroblasts. The egg proteins in these vaccines were believed to trigger an immediate allerg...
Source: Hong Kong Med J - October 1, 2018 Category: General Medicine Authors: Chua GT, Li PH, Ho MH, Lai E, Ngai V, Yau FY, Kwan MY, Leung TF, Lee TH Tags: Hong Kong Med J Source Type: research

The adverse reactions to vaccines practice parameter 10 years on -what have we learned?
CONCLUSION: The risk of reactions to vaccination should be weighed against the risk of suffering a vaccine-preventable disease if the vaccine is withheld. There is no need to ask about egg allergy prior to the administration of influenza vaccines, including on screening forms. In most cases, an allergy to a vaccine constituent is not a contraindication to the vaccine containing it. Patients who have had possible anaphylactic reactions to vaccines should be evaluated by an allergist rather than simply being labeled allergic, because most can go on to receive subsequent doses. Most immediate reactions to COVID-19 vaccines ar...
Source: Annals of Allergy, Asthma and Immunology - February 1, 2022 Category: Allergy & Immunology Authors: John M Kelso Source Type: research

Flu vaccine and egg allergy
Atopic children with asthma are at increased risk from influenza, but are also more likely to be egg allergic. Egg allergy reportedly affects up to 2% of all under-5s. It's important, therefore, to remove obstacles to getting them immunised. All ‘flu vaccines licensed for children are manufactured using hen's eggs, and until now live attenuated influenza vaccine (LAIV; ‘Fluenz’) – an intranasal vaccine which families understandably find more acceptable than injections – was contraindicated in egg allergy. A UK group recently completed the SNIFFLE study (Turner PJ, et al. J Allergy Clin Immunol...
Source: Archives of Disease in Childhood - November 19, 2015 Category: Pediatrics Tags: Miscellanea Source Type: research

Minimizing fucosylation in insect cell-derived glycoproteins reduces binding to IgE antibodies from the sera of patients with allergy.
In this study we evaluated the impact of fucose residues on the allergenic potential of an insect cell-expressed vaccine candidate. In order to block the GDP-L-fucose de novo synthesis pathway, we integrated the Pseudomonas aeruginosa GDP-6-deoxy-D-lyxo-4-hexulose reductase (RMD) gene into a baculovirus backbone. This virus was then used for the expression of soluble influenza A virus hemagglutinin. Expression studies showed that the co-expression of RMD did not influence the overall level of recombinant protein secretion. We confirmed the result of our strategy by analysing PNGase A-released N-glycans using MALDI-TOF-MS. ...
Source: Biotechnology Journal - March 25, 2014 Category: Biotechnology Authors: Palmberger D, Ashjaei K, Strell S, Hoffmann-Sommergruber K, Grabherr R Tags: Biotechnol J Source Type: research