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Infectious Disease: Herpes

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Total 364 results found since Jan 2013.

Leflunomide Induced Atypical DRESS: A Case Report and Literature Review
We report a case of a lady aged 32 years, presented to our hospital with a history of leflunomide intake and symptoms of DRESS.PMID:37223589 | PMC:PMC10201105 | DOI:10.31138/mjr.34.1.91
Source: Herpes - May 24, 2023 Category: Infectious Diseases Authors: Maryam Fatima Salwa Sahar Azimi Soumya Ashwini Madhuri H Radhakrishna Source Type: research

NIH launches trial of investigational genital herpes vaccine
(NIH/National Institute of Allergy and Infectious Diseases) Researchers have launched an early-stage clinical trial of an investigational vaccine designed to prevent genital herpes disease. The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, is sponsoring the Phase I trial, which is being conducted at the NIH Clinical Center in Bethesda, Md.
Source: EurekAlert! - Medicine and Health - November 8, 2013 Category: Global & Universal Source Type: news

“I’m Just In the Band”
Discussion Instrumental music, either as an avocation or profession, provides great pleasure for those performing and listening. Unfortunately it can also cause health problems. Many of the problems are musculoskeletal or neurological in etiology due to overuse and the musician may experience pain. Prelude to pain can include stiffness or tingling or other skin sensations. Musicians may experience weakness, loss of function, control (accuracy) and ability (speed) as well as problems with tone. “The most prevent problems involve overuse of muscles resulting from repetitive movements of playing, often in combination w...
Source: PediatricEducation.org - November 17, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Tonsils diseases, past, present and future and the impact in clinical practice in Brazil.
Authors: Endo LH Abstract A simplified review of the research carried out in Brazil on tonsils is presented: histopathological findings in children's tonsils with allergy, the detection of Epstein-Barr virus, herpes virus (SV1 e SV2, HHV8) and the correlation between tonsil hypertrophy and recurrence of infection is discussed. The role of allergy in children with tonsillitis and/or tonsil and adenoid hypertrophy are analyzed. After participating in the Tonsils Symposium in 1991, the knowledge of tonsils morphology, immunology and histopathology increased, triggering a change in clinical practice in Brazil. PMID...
Source: Advances in Oto-Rhino-Laryngology - December 2, 2014 Category: ENT & OMF Tags: Adv Otorhinolaryngol Source Type: research

How Common Is Hereditary Angioedema?
Discussion Angioedema is edema that is non-pitting, self-limited occurring in non-dependent areas usually in an asymmetric distribution usually on the lips, face, hands, feet, genitals and also in the bowel. It usually develops over minutes to hours (often 1-2 hours) with resolution usually within 24-48 hours. Angioedema often occurs with urticaria but 20% of patients may have isolated angioedema. Acute allergic angioedema is often caused by drugs (including antibiotics and non-steroidal anti-inflammatory drugs), foods, infections, insects, various organic substances (i.e. latex, preservatives, formaldehyde, etc.), and oth...
Source: PediatricEducation.org - October 9, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Sex and prior exposure jointly shape innate immune responses to a live herpesvirus vaccine
CONCLUSIONS: These results together show that prior exposure and sex interact to shape early innate responses that then impact subsequent adaptive immune phenotypes.FUNDING: Intramural Research Program of the NIH, the National Institute of Allergy and Infectious Diseases, and other institutes supporting the Trans-NIH Center for Human Immunology, Autoimmunity, and Inflammation. The vaccine trial was supported through a clinical trial agreement between the National Institute of Allergy and Infectious Diseases and Sanofi Pasteur. Clinical trial number: NCT01915212.PMID:36648132 | DOI:10.7554/eLife.80652
Source: Herpes - January 17, 2023 Category: Infectious Diseases Authors: Foo Cheung Richard Apps Lesia Dropulic Yuri Kotliarov Jinguo Chen Tristan Jordan Marc Langweiler Julian Candia Angelique Biancotto Kyu Lee Han Nicholas Rachmaninoff Harlan Pietz Kening Wang John S Tsang Jeffrey I Cohen Source Type: research

Cutaneous reactions following COVID-19 vaccination assessed by dermatologists: a single-institutional study in Germany
CONCLUSIONS: It can be assumed that vaccination may trigger immune activation-related reactions especially in those patients predisposed to develop respective skin diseases.PMID:36892192 | DOI:10.1111/ddg.14987
Source: Herpes - March 9, 2023 Category: Infectious Diseases Authors: Rosi Wang Sonja Mathes Carla Claussen Tilo Biedermann Knut Brockow Source Type: research

Paediatric bullous dermatoses
Answers to the following quiz questions can be found on page 31. QUESTION 1 Case 1: A 13-month-old boy presented with multiple pruritic tense blisters on the lower abdomen, lower extremities, groin, perineum and perioral areas for the past 1 week. There was no family history of skin disease, and no history of recent upper respiratory tract infections or drug intake prior to the onset of blistering. Physical examination revealed annular erythema with circumferential vesicles and blisters giving a ‘cluster of jewels’ appearance. There was no mucosal involvement. What is the diagnosis? Select one best answer ...
Source: Archives of Disease in Childhood - Education and Practice - January 16, 2013 Category: Pediatrics Authors: Chattopadhyay, M., Burrows, N. P. Tags: Immunology (including allergy), Drugs: infectious diseases, TB and other respiratory infections, Epilepsy and seizures, Child health, Dermatology, Poisoning, Trauma, Occupational and environmental medicine, Injury Dermatophile Source Type: research

The proteome of Toll-like receptor 3–stimulated human immortalized fibroblasts: Implications for susceptibility to herpes simplex virus encephalitis
Conclusions: The present study delineates a number of novel proteins, TLR3-related pathways, and cellular phenotypes that may help elucidate the genetic basis of childhood HSE. Furthermore, our results reveal superoxide dismutase 2 as a potential therapeutic target for amelioration of the neurologic sequelae caused by HSE.
Source: Journal of Allergy and Clinical Immunology - February 25, 2013 Category: Allergy & Immunology Authors: Rebeca Pérez de Diego, Claire Mulvey, Mark Crawford, Matthew W.B. Trotter, Lazaro Lorenzo, Vanessa Sancho-Shimizu, Laurent Abel, Shen-Ying Zhang, Jean-Laurent Casanova, Jasminka Godovac-Zimmermann Tags: Immune deficiencies, infection, and systemic immune disorders Source Type: research

Why is eczema herpeticum unexpectedly rare?
Abstract Atopic dermatitis (AD) is the most common chronic inflammatory skin disease of humans, affecting approximately 17% of children. AD patients are especially susceptible to cutaneous bacterial and viral infections, and may develop severe or fatal herpes simplex virus (HSV) infection (eczema herpeticum, EH), requiring intensive antiviral therapy. However, even though a majority of adults show serologic evidence of previous HSV exposure, EH occurs in less than 3% of AD patients. The unexpected rarity of AD patients with EH (ADEH+) suggests that multiple host factors play a role in the clinical expression of th...
Source: Antiviral Research - May 1, 2013 Category: Virology Authors: Leung DY Tags: Antiviral Res Source Type: research

New insights into atopic dermatitis: role of skin barrier and immune dysregulation.
Abstract Atopic dermatitis (AD) is a chronic inflammatory skin disease that is often associated with the development of food allergy and asthma. New insights into AD reveals an important role for structural abnormalities in the epidermis resulting in a leaky epithelial barrier as well as chronic immune activation that contribute to the pathophysiology of this common skin disease. Patients with AD have a predisposition to colonization or infection by microbial organisms, most notably Staphylococcus aureus and herpes simplex virus (HSV). Measures directed at healing and protecting the skin barrier and controlling th...
Source: Herpes - May 30, 2013 Category: Infectious Diseases Authors: Leung DY Tags: Allergol Int Source Type: research

Vaccination of older adults against herpes zoster is safe and effective
Commentary on: Gagliardi AM, Gomes Silva BN, Torloni MR, et al.. Vaccines for preventing herpes zoster in older adults. Cochrane Database Syst Rev 2012;10:CD008858. Context The problem addressed by this study is that older individuals, for example, those over 60 years of age, are more likely to develop herpes zoster (HZ) than younger people. Older adults are far more likely to develop severe complications of HZ, especially postherpetic neuralgia (PHN). Methods Gagliardi and colleagues reviewed eight randomised controlled trials (RCTs) involving 52 269 participants. Findings By focusing on RCTs and assessing the ...
Source: Evidence-Based Medicine - September 19, 2013 Category: Internal Medicine Authors: Tyring, S. K. Tags: Clinical trials (epidemiology), Immunology (including allergy), Vaccination / immunisation, Neuromuscular disease, Pain (neurology), Peripheral nerve disease, Dermatology, Ethics Online articles Source Type: research

Perioral rashes
Select one best answer from the following for questions 1–3 given below: Lichen planus Oral leukoplakia Acrodermatitis enteropathica Perioral dermatitis Phytophotodermatitis Atopic dermatitis Herpes simplex virus (HSV) infection Answers to the following questions can be found on page 240. Question 1 A 9-year-old girl presents for a rash around her mouth (figure 1). Her past medical history is significant for facial eczema as a toddler, and she has been treating the area with hydrocortisone 2.5% ointment. While using this medication for the past 3 weeks, the rash has not gotten any better. In fact, the rash has a...
Source: Archives of Disease in Childhood - Education and Practice - November 11, 2013 Category: Pediatrics Authors: Lio, P. A., Lee, K. C. Tags: Diarrhoea, Immunology (including allergy), Pain (neurology), Childhood nutrition, Reproductive medicine, Child health, Infant nutrition (including breastfeeding), Dentistry and oral medicine, Dermatology Dermatophile Source Type: research

Herpes encephalitis complicated by cerebral haemorrhage
Case report A 46-year-old, previously well, right-handed man presented with a 1 week history of headache, vomiting and confusion. On examination his temperature was 38.3°C, Glasgow Coma Scale score was 14/15 (E4V4M6) and he was severely expressively dysphasic. There was no limb weakness. Initial blood tests, including C reactive protein, were normal. Cranial CT revealed a hypodense area in the left anteromedial temporal lobe (figure 1). Microscopy of CSF from a lumbar puncture showed a pleocytosis (390x106/ml, lymphocytes 95%), with no organism. On a working diagnosis of herpes simplex virus (HSV) encephalitis, em...
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 13, 2013 Category: Neurosurgery Authors: Lo, W. B., Wilcock, D. J., Carey, M., Albanese, E. Tags: Immunology (including allergy), HIV/AIDS, Coma and raised intracranial pressure, Epilepsy and seizures, Headache (including migraine), Infection (neurology), Pain (neurology) Neurological pictures Source Type: research