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Infectious Disease: Coronavirus

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Total 2387 results found since Jan 2013.

Does Asthma Increase the Mortality of Patients with COVID-19?: A Systematic Review and Meta-Analysis
The purpose of this systematic review and meta-analysis was to explore the literature and collate data comparing the mortality of coronavirus disease 2019 (COVID-19) patients with and without asthma. The databases PubMed, Scopus, Embase, Google Scholar, and medRxiv.org were searched for studies comparing the clinical outcomes of asthmatic patients with those of nonasthmatic patients diagnosed with COVID-19. Mortality data were summarized using the Mantel-Haenszel OR with 95% CI in a random-effects model. Five retrospective studies met the inclusion criteria. A meta-analysis of data from 744 asthmatic patients and 8,151 non...
Source: International Archives of Allergy and Immunology - September 22, 2020 Category: Allergy & Immunology Source Type: research

Public Inspection: DOD: TRICARE Coverage of National Institute of Allergy and Infectious Disease Coronavirus Disease 2019 Clinical Trials
Pre-publication notice of an interim final rule from the Department of Defense temporarily modifying the TRICARE regulation by adding coverage for National Institute of Allergy and Infectious Disease (NIAID)-sponsored clinical trials for the treatment or prevention of COVID-19. This interim final rule is effective upon publication of this notice, which is scheduled for October 30, 2020. Comments are due within 30 days of the publication of this notice.
Source: Federal Register updates via the Rural Assistance Center - October 29, 2020 Category: Rural Health Source Type: news

DOD: TRICARE Coverage of National Institute of Allergy and Infectious Disease Coronavirus Disease 2019 Clinical Trials
Notice of an interim final rule from the Department of Defense temporarily modifying the TRICARE regulation by adding coverage for National Institute of Allergy and Infectious Disease (NIAID)-sponsored clinical trials for the treatment or prevention of COVID-19. This interim final rule is effective October 30, 2020. Comments are due by November 30, 2020.
Source: Federal Register updates via the Rural Assistance Center - October 30, 2020 Category: Rural Health Source Type: news

Prophylactic and therapeutic topical povidone ‐iodine in coronavirus disease 2019 (COVID‐19): What is the evidence?
International Forum of Allergy& Rhinology, EarlyView.
Source: International Forum of Allergy and Rhinology - November 10, 2020 Category: Allergy & Immunology Authors: Carol H. Yan, Benjamin S. Bleier Tags: EDITORIAL Source Type: research

Interim analysis of an open ‐label randomized controlled trial evaluating nasal irrigations in non‐hospitalized patients with coronavirus disease 2019
International Forum of Allergy& Rhinology, EarlyView.
Source: International Forum of Allergy and Rhinology - October 20, 2020 Category: Allergy & Immunology Authors: Kyle S. Kimura, Michael H. Freeman, Bronson C Wessinger, Veerain Gupta, Quanhu Sheng, Li Ching Huang, Kate Von Wahlde, Suman R. Das, Naweed I. Chowdhury, Justin H. Turner Tags: RESEARCH NOTE Source Type: research

Reply
We thank Lipworth et  al1 for their correspondence regarding our article recently published in the Journal of Allergy and Clinical Immunology.2 We agree that it is currently unclear whether inhaled corticosteroid (ICS) use in chronic obstructive pulmonary disease (COPD) imparts an overall protective or detrimental effe ct on susceptibility to coronavirus disease 2019 (COVID-19). Theoretically, any potentially beneficial effects of ICS related to COVID-19, such as angiotensin-converting enzyme 2 attenuation and/or suppression of inflammation, could be offset by detrimental effects.
Source: Journal of Allergy and Clinical Immunology - December 30, 2020 Category: Allergy & Immunology Authors: Hugo Farne, Aran Singanayagam Tags: Correspondence Source Type: research

Summary of COVID-19 medicines guidance: Allergy and immunology, Specialist Pharmacy Service (published 6th January 2021)
This page summarises and signposts to medicine related guidance we ' re aware of from professional and government bodies relating to coronavirus and allergy and immunology conditions.
Source: Current Awareness Service for Health (CASH) - January 7, 2021 Category: Consumer Health News Source Type: news

High frequency of smell and taste dysfunctions in allergy health care professionals suffering from COVID-19.
CONCLUSIONS: STD is a common symptom in COVID-19, even as a unique or preceding symptom. HCP who declared smell dysfunction (SD) were younger than those not affected with STD. Taste dysfunction (TD) may imply more systemic involvement in COVID-19-positive HCP. PMID: 33465033 [PubMed - as supplied by publisher]
Source: Journal of Investigational Allergology and Clinical Immunology - January 19, 2021 Category: Allergy & Immunology Authors: Amérigo DA, Cubero JL, Colás C, Alobid I, Mullol J, Valero A Tags: J Investig Allergol Clin Immunol Source Type: research

Dynamic Changes of Lymphocyte Subsets in the Course of COVID-19
Conclusion: We found an increasing trend in total T cells, T helpers, cytotoxic T cells, activated lymphocytes, and natural killer cells among responders. This trend was not statistically significant among nonresponders. The findings of this study may enhance our knowledge about the pathogenesis of COVID-19.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - January 26, 2021 Category: Allergy & Immunology Source Type: research

Principles and Challenges in anti-COVID-19 Vaccine Development
The number of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected patients keeps rising in most of the European countries despite the pandemic precaution measures. The current antiviral and anti-inflammatory therapeutic approaches are only supportive, have limited efficacy, and the prevention in reducing the transmission of SARS-CoV-2 virus is the best hope for public health. It is presumed that an effective vaccination against SARS-CoV-2 infection could mobilize the innate and adaptive immune responses and provide a protection against severe forms of coronavirus disease 2019 (COVID-19) disease. As the ra...
Source: International Archives of Allergy and Immunology - February 1, 2021 Category: Allergy & Immunology Source Type: research

Quantitative Measurement of IgG to Severe Acute Respiratory Syndrome Coronavirus-2 Proteins Using ImmunoCAP
Conclusions: We have described a quantitative assay to measure IgG to SARS-CoV-2 that could be used in clinical and research laboratories and implemented at scale. The assay can easily be adapted to measure IgG to mutated COVID-19 proteins, has good performance characteristics, and has a readout in standardized units.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - February 23, 2021 Category: Allergy & Immunology Source Type: research

COVID-19 Associated Multisystem Inflammatory Syndrome: A Systematic Review and Meta-analysis
This study was aimed to describe clinical manifestation and outcomes of MIS-C associated with COVID-19. This systematic review and meta-analysis were conducted on all available literature until July 3rd, 2020. The screening was done by using the following keywords: ("novel coronavirus" Or COVID-19 or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or coronavirus) and ("MIS-C" or "multisystem inflammatory" or Kawasaki). Data on gender, ethnicity, clinical presentations, need for mechanical ventilation or admission to intensive care unit (ICU), imaging, cardiac complications, and COVID-19 laboratory results were...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 19, 2021 Category: Allergy & Immunology Authors: Ashkan Baradaran Abdolreza Malek Nasrin Moazzen Zahra Abbasi Shaye Source Type: research

Procalcitonin Has Good Accuracy for Prognosis of Critical Condition and Mortality in COVID-19: A Diagnostic Test Accuracy Systematic Review and Meta-analysis
Iran J Allergy Asthma Immunol. 2020 Dec 19;19(6):557-569. doi: 10.18502/ijaai.v19i6.4926.ABSTRACTSeveral reports have determined that changes in white blood cell counts and inflammatory biomarkers are related to disease outcome of coronavirus disease 2019 (COVID-19) and they can be utilized as prognostic biomarkers. For introducing a factor as a diagnostic/prognostic biomarker, diagnostic test accuracy (DTA) systematic review and meta-analysis are recommended. For the first time, we aimed to determine the accuracies of white blood cell counts and inflammatory biomarkers for prognosis of COVID-19 patient's outcome by a DTA ...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 19, 2021 Category: Allergy & Immunology Authors: Mohammad Erfan Zare Yanzhong Wang Atefeh Nasir Kansestani Afshin Almasi Jun Zhang Source Type: research

Prevalence of SARS-CoV-2 in Patients with Severe Pneumonia in Khuzestan Province, Iran
This study aimed to evaluate the frequency of SARS-CoV-2 in hospitalized patients with an acute respiratory infection (ARI). During an outbreak of the SARS-CoV-2, the nasopharyngeal and oropharyngeal swabs were collected from 909 hospitalized patients with severe pneumonia, including 517 (56.9%) males and 392 (43.1%) females. All the collected samples were from different cities of Khuzestan province from 19 February to- 27 March 2020. The RNA was extracted from samples and subjected to real-time polymerase chain reaction (PCR) tests for the detection of the SARS-CoV-2. Simultaneously, the computerized tomography (CT) scan ...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 19, 2021 Category: Allergy & Immunology Authors: Farhad Abolnezhadian Manoochehr Makvandi Seyed Mohammad Alavi Azarakhsh Azaran Shahram Jalilian Mohammad Rashno Gholam Abbas Kaydani Maniya Arshadi Seyed Mehdi Hosseinizadeh Hatam Boostani Seyed Saeed Seyedian Sasan Moogahi Shokrolah Salmanzadeh Mehran Va Source Type: research