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Infectious Disease: Pandemics
Nutrition: Herbs

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Total 360 results found since Jan 2013.

Antibacterial activity of Lagerstreomia speciosa and its active compound, corosolic acid, enhances cefotaxime inhibitory activity against Staphylococcus aureus
CONCLUSIONS: L. speciosa leaves and bark extract and its active compound, corosolic acid, could be used as a potential anti-Staphylococcus aureus treatment to enhance the therapeutic use of cefotaxime.PMID:37541956 | DOI:10.1093/jambio/lxad171
Source: Mol Biol Cell - August 4, 2023 Category: Molecular Biology Authors: Sylvia Sinelius Jullietta Lady Michellina Yunardy Enty Tjoa Agustina D R Nurcahyanti Source Type: research

Terpenoid phytocompounds from mangrove plant Xylocarpus moluccensis as possible inhibitors against SARS-CoV-2: In silico strategy
Comput Biol Chem. 2023 Jul 6;106:107912. doi: 10.1016/j.compbiolchem.2023.107912. Online ahead of print.ABSTRACTCOVID-19 shook the world during the pandemic, where the climax it reached was vaccine manufacturing at an unfathomable pace. Alternative promising solutions to prevent infection from SARS-CoV-2 and its variants will remain crucial in the years to come. Due to its key role in viral replication, the major protease (Mpro) enzyme of SARS-CoV-2 can be an attractive therapeutic target. In the present work, natural terpenoids from mangrove medicinal plant Xylocarpus moluccensis (Lam.) M. Roem. were screened using comput...
Source: Computational Biology and Chemistry - July 16, 2023 Category: Bioinformatics Authors: Kiran Bharat Lokhande Arti Kale Bhagyashree Shahakar Ashish Shrivastava Neelu Nawani K Venkateswara Swamy Ashutosh Singh Sarika Vishnu Pawar Source Type: research

COVID-19 Associated Thyroid Dysfunction and Other Comorbidities and Its Management Using Phytochemical-Based Therapeutics- A Natural Way
Biosci Rep. 2023 May 2:BSR20230293. doi: 10.1042/BSR20230293. Online ahead of print.ABSTRACTThe present severe acute respiratory syndrome-2 (SARS-CoV-2) mediated Coronavirus pandemic (COVID-19) and post-COVID-19 complications affect human life drastically. Patients who have been cured of COVID-19 infection are now experiencing post-COVID-19 associated comorbidities, which have increased mortality rates. The SARS-CoV-2 infection distresses the lungs, kidneys, gastrointestinal tract, and various endocrine glands, including the thyroid. The emergence of variants which includes Omicron (B.1.1.529) and its lineages threaten the...
Source: Bioscience Reports - May 22, 2023 Category: Biomedical Science Authors: Arpana Parihar Shivani Malviya Raju Khan Ajeet Kaushik Ebrahim Mostafavi Source Type: research

Antiviral Flavonoids: A natural scaffold with prospects as phytomedicines against SARS-CoV2
Mini Rev Med Chem. 2023 May 3. doi: 10.2174/1389557523666230503105053. Online ahead of print.ABSTRACTFlavonoids are vital candidates to fight against a wide range of pathogenic microbial infections. Due to their therapeutic potential, many flavonoids from the herbs of traditional medicine systems are now being evaluated as lead compounds to develop potential antimicrobial hits. The emergence of SARS-CoV-2 caused one of the deadliest pandemics that has ever been known to mankind. To date, more than 600 million confirmed cases of SARS-CoV2 infection have been reported worldwide. Situations are worse due to the unavailability...
Source: Mini Reviews in Medicinal Chemistry - May 4, 2023 Category: Chemistry Authors: Chiranjeet Saha Roumi Naskar Sandipan Chakraborty Source Type: research

Natural Products as a Potential Source of Promising Therapeutics for COVID-19 and Viral Diseases
CONCLUSION: The immune system benefits from natural products and many of these play a role in activating antibody creation, maturation of immune cells, and stimulation of innate and adaptive immune responses. The lack of particular antivirals for SARS-CoV-2 means that apitherapy might be a viable option for reducing the hazards associated with COVID-19 in the absence of specific antivirals.PMID:37096202 | PMC:PMC10122587 | DOI:10.1155/2023/5525165
Source: Evidence-based Complementary and Alternative Medicine - April 25, 2023 Category: Complementary Medicine Authors: Soheila Bafandeh Ehsaneh Khodadadi Khudaverdi Ganbarov Mohammad Asgharzadeh Şükran Köse Hossein Samadi Kafil Source Type: research

Traditional Chinese Medicine as the preventive and therapeutic remedy for COVID-19
This article explored the Chinese national authorities' guidelines from 2003 to 2020, the scientific data in public databases for the recommended TCM remedies, and their potential mechanistic actions in COVID-19 management. Several TCM herbs and formulations could potentially benefit COVID-19 management. The recommended TCM oral preparations list are Huoxiang zhengqi, Jinhua Qinggan, Lianhua Qingwen, and Shufeng jiedu; the recommended injection preparations comprise Xiyanping Xuebijing, Re-Du-Ning, Tanreqing, Xingnaojing, Shenfu, Shengmai, and Shenmai. TCM remedies are viable options for symptom alleviation and management ...
Source: Current Medicinal Chemistry - March 31, 2023 Category: Chemistry Authors: Amin Gasmi Torsak Tippairote Pavan Kumar Mujawdiya Alain Menzel Roman Lysiuk Mariia Shanaida Larysa Lenchyk Massimiliano Peana Geir Bj ørklund Source Type: research