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Controlled delivery of ciprofloxacin and ivacaftor via sinus stent in a preclinical model of Pseudomonas sinusitis
ConclusionThe CISS had robust clinical efficacy in treatingP aeruginosa rabbit sinusitis. The innovative design of double ‐layered drug coating on the surface of the biodegradable stent may provide therapeutic advantages over current treatment strategies forP aeruginosa sinusitis.
Source: International Forum of Allergy and Rhinology - December 22, 2019 Category: Allergy & Immunology Authors: Dong ‐Jin Lim, Justin McCormick, Daniel Skinner, Shaoyan Zhang, Jeffrey B. Elder, John G. McLemore, Mark Allen, John Martin West, Jessica W. Grayson, Steven M. Rowe, Bradford A. Woodworth, Do‐Yeon Cho Tags: ORIGINAL ARTICLE Source Type: research

In ‐vitro evaluation of a ciprofloxacin and azithromycin sinus stent for Pseudomonas aeruginosa biofilms
ConclusionThe CASS maintains a uniform coating and sustained delivery of ciprofloxacin and azithromycin, providing anti ‐biofilm activities againstP aeruginosa. Further studies evaluating the efficacy of CASS in a preclinical model are planned.
Source: International Forum of Allergy and Rhinology - November 5, 2019 Category: Allergy & Immunology Authors: Dong ‐Jin Lim, Daniel Skinner, John Mclemore, Nick Rivers, Jeffrey Brent Elder, Mark Allen, Connor Koch, John West, Shaoyan Zhang, Harrison M. Thompson, Justin P. McCormick, Jessica W. Grayson, Do‐Yeon Cho, Bradford A. Woodworth Tags: ORIGINAL ARTICLE Source Type: research

In ‐vitro evaluation of a ciprofloxacin‐ and ivacaftor‐coated sinus stent against Pseudomonas aeruginosa biofilms
ConclusionThe CISS maintains a uniform coating and sustained delivery of drugs providing a marked reduction inP aeruginosa biofilm formation. Further studies evaluating the efficacy of CISS in a preclinical model are planned.
Source: International Forum of Allergy and Rhinology - January 31, 2019 Category: Allergy & Immunology Authors: Do ‐Yeon Cho, Dong‐Jin Lim, Calvin Mackey, Christopher G. Weeks, Jaime A. Peña Garcia, Daniel Skinner, Shaoyan Zhang, Justin McCormick, Bradford A. Woodworth Tags: ORIGINAL ARTICLE Source Type: research

Tratamiento ambulatorio de la diverticulitis aguda no complicada. An álisis de nuestra experiencia.
Conclusions: Outpatient treatment of uncomplicated acute diverticulitis can be performed successfully in most patients allowing an important cost savings. PMID: 30600803 [PubMed - in process]
Source: Cirugia y Cirujanos - January 3, 2019 Category: Surgery Authors: García-Marín A, Rodríguez-Cazalla L, Bernabeu-Herráiz C, Madrid-Baños B, Morales-Calderón M, Compañ-Rosique A Tags: Cir Cir Source Type: research

Ivacaftor, a Cystic Fibrosis Transmembrane Conductance Regulator Potentiator, Enhances Ciprofloxacin Activity Against Pseudomonas aeruginosa.
CONCLUSION: Ivacaftor enhanced ciprofloxacin's antimicrobial activity against P. aeruginosa. Further studies evaluating the efficacy of ivacaftor/ciprofloxacin combination for P. aeruginosa for CF CRS are warranted. PMID: 30585080 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - December 25, 2018 Category: ENT & OMF Authors: Cho DY, Lim DJ, Mackey C, Skinner D, Zhang S, McCormick J, Woodworth BA Tags: Am J Rhinol Allergy Source Type: research

Preclinical therapeutic efficacy of the ciprofloxacin ‐eluting sinus stent for Pseudomonas aeruginosa sinusitis
ConclusionAlthough this study had a small sample size, we identified robust therapeutic efficacy of the CSS by reducing bacterial load and biofilm formation of P aeruginosa in a preclinical model of sinusitis after placement for 2 weeks.
Source: International Forum of Allergy and Rhinology - January 15, 2018 Category: Allergy & Immunology Authors: Do ‐Yeon Cho, Dong‐Jin Lim, Calvin Mackey, Daniel Skinner, Christopher Weeks, Gobind S. Gill, Robert W. Hergenrother, William E. Swords, Bradford A. Woodworth Tags: ORIGINAL ARTICLE Source Type: research

Preventing Medication Errors: Lessons From a Patient
A Nurse Aide, an Emergency Room Clerk, and a Patient I have great appreciation for doctors and nurses, hospitals, and patients. In high school I worked as a nurse aide in a convalescent home. I fed, dressed, and showered elderly patients, many of them immobile. I shaved gentlemen's facial stubble and polished ladies' fingernails. In college and in graduate school, I worked as an emergency room clerk. I witnessed a lot, including amazing doctors and nurses caring for patients and saving lives. I have also been a patient. First, when I had an appendectomy at age eight and then when I gave natural childbirth twice. All were...
Source: Healthy Living - The Huffington Post - May 2, 2016 Category: Consumer Health News Source Type: news