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Drug: Penicillin

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Total 1616 results found since Jan 2013.

Long-Term Follow-Up After Penicillin Allergy Delabeling in Ambulatory Patients
ConclusionsPenicillin allergy annulling via OCT has proven to be effective. Most of the patients who previously avoided penicillins have reused penicillins safely.
Source: The Journal of Allergy and Clinical Immunology: In Practice - December 29, 2018 Category: Allergy & Immunology Source Type: research

Patient and primary care physician perceptions of penicillin allergy testing and subsequent use of penicillin containing antibiotics: A qualitative study
ConclusionsClinicians would benefit from information about penicillin allergy testing in order to be able to use these services appropriately, and to discuss referral with patients. Patients might be more motivated to seek testing if they were more informed regarding its benefits. Good communication between primary and secondary care would facilitate the updating of medical records, and promote better patient education.
Source: The Journal of Allergy and Clinical Immunology: In Practice - March 14, 2019 Category: Allergy & Immunology Source Type: research

Safety and Outcomes of Penicillin Allergy Evaluation in Pregnant Women
CONCLUSION: PST and IDC can be safely conducted in pregnant women. When evaluated as low risk, the majority of women tolerate IDC and can receive penicillin intrapartum without adverse reactions or negative pregnancy outcomes.PMID:35123076 | DOI:10.1016/j.anai.2022.01.032
Source: Annals of Allergy, Asthma and Immunology - February 5, 2022 Category: Allergy & Immunology Authors: Vima Patel Patrick K Gleeson Kathryn Delaney Steven J Ralston Scott Feldman Olajumoke Fadugba Source Type: research

Antibiotic Prescribing Practices Differ between Patients with Penicillin Intolerance and Penicillin Allergy Labels
Conclusions: This study supports that prescribing practices differ between patients with penicillin allergy labels and intolerance labels. Penicillin challenges may be undertaken safely in the inpatient setting. Further studies are required to investigate how best to interrogate penicillin allergy labels in this cohort.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - November 11, 2022 Category: Allergy & Immunology Source Type: research

Parental Perspective on Penicillin Allergy Delabeling in a Pediatric Emergency Department
CONCLUSION: Most parents of low-risk PCN allergic children are uncomfortable with oral challenge or delabeling in the PED. Prior to implementing oral challenges in PEDs, efforts should be made to highlight the safety of oral challenging low-risk children, the benefits and risks of alternative antibiotics, and the minimal impact that FH has on PCN allergy.PMID:36990206 | DOI:10.1016/j.anai.2023.03.023
Source: Annals of Allergy, Asthma and Immunology - March 29, 2023 Category: Allergy & Immunology Authors: Cheryl Yang Jessica K Graham David Vyles Jan Leonard Chisom Agbim Rakesh D Mistry Source Type: research

Clinical Outcomes following Inpatient Penicillin Allergy Testing: A Systematic Review and Meta ‐analysis
ConclusionsInpatient penicillin allergy testing is safe and effective in ruling out penicillin allergy. The rate of negative tests is comparable to outpatient and perioperative data. Patients with a documented penicillin allergy who require penicillin should be tested during hospitalization given its benefit for individual patient outcomes and antibiotic stewardship.This article is protected by copyright. All rights reserved.
Source: Allergy - March 29, 2017 Category: Allergy & Immunology Authors: Keith A. Sacco, Allan Bates, Tara J. Brigham, J. Saadi ‐Imam, M Caroline Burton Tags: Review Source Type: research

The Cost of Penicillin Allergy Evaluation
Conclusions Using TDABC, penicillin allergy evaluation costs $220; even with varied assumptions adjusting for operational challenges, clinical setting, and expanded testing, penicillin allergy evaluation still costs only about $540. This modest investment may be offset for patients treated with costly alternative antibiotics that also may result in adverse consequences.
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 22, 2017 Category: Allergy & Immunology Source Type: research

Role of clinical history in beta-lactam hypersensitivity
Purpose of Review Understand how the clinical history has been used to risk stratify patients reporting a beta-lactam allergy, both in clinical care pathways and predictive models. Recent findings Drug allergy clinical care pathways have emerged as a safe and effective method of stratifying patients with a reported beta-lactam allergy into risk categories, with ‘low-risk’ patients able to proceed straight to direct challenges or test doses. These methods have streamlined antibiotic stewardship policies and penicillin allergy de-labeling. However, how to define ‘low-risk’ has been subject to much debate. ...
Source: Current Opinion in Allergy and Clinical Immunology - July 14, 2021 Category: Allergy & Immunology Tags: DRUG ALLERGY: Edited by Miguel Blanca and Paul Whitaker Source Type: research

Penicillin allergy de-labeling: Opportunities for implementation and dissemination
Although existing as a safety measure to prevent iatrogenic harm, unconfirmed penicillin allergy labels have a negative impact on personal and public health. One downstream effect of unconfirmed penicillin allergy is the continued emergence and transmission of resistant bacteria and associated healthcare cost. Recognizing the consequences of inaccurate penicillin allergy labels, professional and public health organizations have started promoting the adoption of proactive penicillin allergy evaluations, with the ultimate goal of removing the penicillin allergy label when the allergy is disproved, also known as penicillin al...
Source: Annals of Allergy, Asthma and Immunology - December 19, 2022 Category: Allergy & Immunology Authors: Upeka Samarakoon, John Accarino, Alysse Wurcel, Jordon Jaggers, Allen Judd, Kimberly Blumenthal Source Type: research

Penicillin allergy delabeling
Although existing as a safety measure to prevent iatrogenic harm, unconfirmed penicillin allergy labels have a negative impact on personal and public health. One downstream effect of unconfirmed penicillin allergy is the continued emergence and transmission of resistant bacteria and their associated health care costs. Recognizing the consequences of inaccurate penicillin allergy labels, professional and public health organizations have started promoting the adoption of proactive penicillin allergy evaluations, with the ultimate goal of removing the penicillin allergy label when the allergy is disproved, also known as penic...
Source: Annals of Allergy, Asthma and Immunology - December 19, 2022 Category: Allergy & Immunology Authors: Upeka Samarakoon, John Accarino, Alysse G. Wurcel, Jordon Jaggers, Allen Judd, Kimberly G. Blumenthal Tags: CME Review Source Type: research

Efficacy and safety of five-day challenge for the evaluation of non-severe amoxicillin allergy in children
Conclusion Five-day challenge is a safe and effective way to rule out nonimmediate amoxicillin allergy, and it ensures a better compliance with future penicillin use.
Source: The Journal of Allergy and Clinical Immunology: In Practice - February 7, 2018 Category: Allergy & Immunology Source Type: research