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Drug: Amoxicillin

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Treatment of < em > Helicobacter pylori < /em > infection in the presence of penicillin allergy
World J Gastroenterol. 2021 Nov 28;27(44):7661-7668. doi: 10.3748/wjg.v27.i44.7661.ABSTRACTTherapy of Helicobacter pylori (H.pylori) requires a combination of antibiotics together with an acid suppressing agent; most treatment regimens include Amoxicillin as one of the antibiotics, which is an important constituent as resistance to it is low. However, allergies to the penicillin group of antibiotics are not uncommon, and treating H.pylori infection in such individuals can be challenging due to the restricted choice of regimens. The aim of this review is to summarise the evidence for therapeutic options in patients with H.p...
Source: World Journal of Gastroenterology : WJG - December 15, 2021 Category: Gastroenterology Authors: Amit Kumar Dutta Perminder Singh Phull Source Type: research

Erratum
In the article “Predictive factors of amoxicillin immediate hypersensitivity and validation of PEN-FAST clinical decision ruletitle of article” by Piotin et al (Ann Allergy Asthma Immunol 128 (2022) 27−32), Figure 3 was incorrect. On page 29 in the paragraph under heading “Validation of PEN-FAST in Predic ting a Positive Penicillin Allergy Test” on line 7-8, the sentence should appear as follows: “The specificity and sensitivity to identify amoxicillin allergy were 0.56 (95% CI, 0.41- 0.71) and 0.98 (95% CI, 0.93-1.00), respectively.”
Source: Annals of Allergy, Asthma and Immunology - April 16, 2022 Category: Allergy & Immunology Source Type: research

Corrigendum
In the article “Predictive factors of amoxicillin immediate hypersensitivity and validation of PEN-FAST clinical decision ruletitle of article” by Piotin et al (Ann Allergy Asthma Immunol 128 (2022) 27−32), Figure 3 was incorrect. On page 29 in the paragraph under heading “Validation of PEN-FAST in Predic ting a Positive Penicillin Allergy Test” on line 7-8, the sentence should appear as follows: “The specificity and sensitivity to identify amoxicillin allergy were 0.56 (95% CI, 0.41- 0.71) and 0.98 (95% CI, 0.93-1.00), respectively.”
Source: Annals of Allergy, Asthma and Immunology - April 16, 2022 Category: Allergy & Immunology Source Type: research

Amoxicillin hypersensitivity: patient outcomes in a seven-year retrospective study
CONCLUSION: The negative predictive value of skin tests in both immediate and non-immediate hypersensitivity reactions is excellent and excludes severe allergy. Non-immediate hypersensitivity is rare. Confirmed hypersensitivity is more likely if amoxicillin-clavulanic acid is the index drug. Cross-reactivity was more common in patients presenting with immediate hypersensitivity, most commonly involving benzylpenicillin. A minority of patients were allergic to clavulanic acid.PMID:35788420 | DOI:10.1016/j.anai.2022.06.021
Source: Annals of Allergy, Asthma and Immunology - July 5, 2022 Category: Allergy & Immunology Authors: Xingyue Maria Wang Lucinda Kennard Krzysztof Rutkowski Maria Eduarda Ferreira Bruco Rita Mirakian Annette Wagner Source Type: research

Why should I be evaluated for a penicillin allergy?
Taking action to be evaluated for a penicillin allergy can impact your health, safety and wallet. According to the Centers for Disease Control and Prevention, 10% of the U.S. population reports a penicillin allergy, but less than 1% is allergic after testing. Common penicillins include ampicillin, amoxicillin and Augmentin. Penicillin allergy is an abnormal reaction of your immune system to the antibiotic drug prescribed for treating various bacterial infections. These medications are used often to treat ear…
Source: News from Mayo Clinic - December 14, 2022 Category: Databases & Libraries Source Type: news

Clavulanic Acid Is a Leading Culprit Beta-Lactam in Immediate Allergic Reactions to Penicillins
CONCLUSIONS: Selective immediate reactions to clavulanate accounted for over a third of cases with confirmed reactions after amoxicillin-clavulanate intake, with more than half experiencing anaphylaxis. Within this group, skin test sensitivity was below 50%. People taking amoxicillin-clavulanate may also be co-sensitized to both drugs.PMID:37021506 | DOI:10.4168/aair.2023.15.2.201
Source: Allergy, Asthma and Immunology Research - April 6, 2023 Category: Allergy & Immunology Authors: Isabel Torres-Rojas Diana P érez-Alzate Maria Luisa Somoza Ana Prieto-Moreno Pfeifer Elisa Haroun Diaz Teodorikez W Jimenez-Rodriguez Javier Fern ández Sánchez Francisco J Ruano Miguel Blanca Natalia Blanca-L ópez Source Type: research