Clavulanic Acid Is a Leading Culprit Beta-Lactam in Immediate Allergic Reactions to Penicillins

CONCLUSIONS: Selective immediate reactions to clavulanate accounted for over a third of cases with confirmed reactions after amoxicillin-clavulanate intake, with more than half experiencing anaphylaxis. Within this group, skin test sensitivity was below 50%. People taking amoxicillin-clavulanate may also be co-sensitized to both drugs.PMID:37021506 | DOI:10.4168/aair.2023.15.2.201

Source: Allergy, Asthma and Immunology Research - April 6, 2023 Category: Allergy & Immunology Authors: Isabel Torres-Rojas Diana P érez-Alzate Maria Luisa Somoza Ana Prieto-Moreno Pfeifer Elisa Haroun Diaz Teodorikez W Jimenez-Rodriguez Javier Fern ández Sánchez Francisco J Ruano Miguel Blanca Natalia Blanca-L ópez Source Type: research