Filtered By:
Drug: Methotrexate
This page shows you your search results in order of relevance. This is page number 16.
Order by Relevance | Date
Total 6619 results found since Jan 2013.
Promising Results With Sarilumab in Rheumatoid ArthritisPromising Results With Sarilumab in Rheumatoid Arthritis
The IL-6-receptor inhibitor sarilumab was superior to placebo when added to methotrexate in a phase 3 registration trial of patients with moderate to severe rheumatoid arthritis. Medscape Medical News
Source: Medscape Medical News Headlines - June 13, 2014 Category: Consumer Health News Tags: Rheumatology News Source Type: news
Degrading Anticancer Drugs in the Medical Environment Using a Visible Light-driven Photocatalyst.
In this study, we evaluated anticancer drug degradation using a visible light-driven photocatalyst (Cu/WO3). Anticancer drugs [cyclophosphamide (CPA), paclitaxel (PTX), methotrexate (MTX), irinotecan (CPT-11), cytarabine (Ara-C), and 5-fluorouracil (5-FU)], were experimentally deposited on a stainless steel plate. The visible light-driven photocatalytic agent (0.075% Cu/WO3 solution) was sprayed onto the plate, and the plate was then left under a fluorescent lamp for 12 h. The anticancer drugs remaining on the plate were assayed by high-performance liquid chromatography (HPLC). CPA, PTX, MTX, CPT-11, Ara-C, and 5-FU were f...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - August 9, 2014 Category: Drugs & Pharmacology Authors: Sato J, Kikuchi S, Kudo K Tags: Yakugaku Zasshi Source Type: research
Juvenile Arthritis: Pattern of Drug Withdrawal Affects FlareJuvenile Arthritis: Pattern of Drug Withdrawal Affects Flare
Children receiving combination therapy for juvenile arthritis were less likely to flare when withdrawing methotrexate first compared with withdrawing tumor necrosis factor inhibitors first. Medscape Medical News
Source: Medscape Medical News Headlines - October 6, 2014 Category: Consumer Health News Tags: Rheumatology News Source Type: news
Effectiveness of medical treatment with methotrexate for interstitial pregnancy
ConclusionSystemic MTX is effective for treatment of intact interstitial pregnancy in haemodynamically stable women. The success rate is increased with uterine artery MTX injection as second‐line treatment.
Source: The Australian and New Zealand Journal of Obstetrics and Gynaecology - October 22, 2014 Category: OBGYN Authors: Liran Hiersch, Haim Krissi, Eran Ashwal, Anat From, Arnon Wiznitzer, Yoav Peled Tags: Original Article Source Type: research
Topical methotrexate pretreatment enhances the therapeutic effect of topical 5-aminolevulinic acid-mediated photodynamic therapy on hamster buccal pouch precancers
Conclusion We conclude that topical MTX-pretreatment can increase intracellular PpIX production in hamster buccal pouch precancerous lesions and significantly improves the outcomes of the precancerous lesions treated with topical ALA-PDT.
Source: Journal of the Formosan Medical Association - October 12, 2014 Category: Journals (General) Source Type: research
RA: Patients in Remission Benefit From Etanercept TaperRA: Patients in Remission Benefit From Etanercept Taper
In patients with RA who achieve remission while taking etanercept and methotrexate, tapering the combination maintained remission better than methotrexate only or placebo. Medscape Medical News
Source: Medscape Medical News Headlines - November 6, 2014 Category: Consumer Health News Tags: Rheumatology News Source Type: news
Synthesis and screening of some new fluorinated quinazolinone–sulphonamide hybrids as anticancer agents
Conclusions The newly synthesized compounds may provide a valuable template for future design and optimization to produce analogues that act as more active anticancer agents.
Source: Journal of Taibah University Medical Sciences - March 12, 2015 Category: Universities & Medical Training Source Type: research
Management and prognosis of patients with brain metastasis from gestational trophoblastic neoplasia: a 24-year experience in Peking union medical college hospital
Conclusions:
Patients with brain metastasis from GTN have favorable outcome by multidrug chemotherapy and adjuvant therapies. Nevertheless, the prognosis is poor if the patients had previous multidrug failure chemotherapy history, concomitant with renal metastasis, or FIGO score over 12. Initial treatment with FAEV combined with intrathecal methotrexate chemotherapy can bring bright prospect to patients with brain metastases from GTN.
Source: BioMed Central - April 27, 2015 Category: Journals (General) Authors: Changji XiaoJunjun YangJing ZhaoTong RenFengzhi FengXirun WanYang Xiang Source Type: research
Bevacizumab might potentiate the chemotherapeutic effect in breast cancer patients with leptomeningeal carcinomatosis
Conclusion Bevacizumab plus etoposide and cisplatin might be a new option for breast cancer patients with LC. Further prospective study is warranted.
Source: Journal of the Formosan Medical Association - May 13, 2015 Category: Journals (General) Source Type: research
Hidradenitis Suppurativa Management in the United States: An Analysis of the National Ambulatory Medical Care Survey and MarketScan Medicaid Databases
Conclusions: Our data showing a maximum of 0.06% of the population being treated for HS in a given year are consistent with the low estimates of HS prevalence. Compared to the current prescribing patterns, the more frequent prescription of biologics and systemic treatments may yield better outcomes.Skin Appendage Disord 2015;1:65-73
Source: Skin Appendage Disorders - June 20, 2015 Category: Dermatology Source Type: research
The impact of a computerized physician order entry system on medical errors with antineoplastic drugs 5 years after its implementation
The objectives of this study were to determine the impact of a CPOE on the number of MEs and to identify the types of MEs in prescriptions issued by the Haematology Department 5 years after the implementation of the CPOE system.
MethodsWe conducted a prospective analytical study on the implementation of a CPOE system at the Pharmacy Department of the Hospital Ramon y Cajal (Madrid, Spain). The study comprised three phases: a pre‐implementation phase, an implementation phase conducted in the Haematology Department and a post‐implementation phase, which was conducted 5 years after the implementation of the CPOE system....
Source: Journal of Clinical Pharmacy and Therapeutics - July 14, 2015 Category: Drugs & Pharmacology Authors: M. Sanchez Cuervo, A. Rojo Sanchis, C. Pueyo Lopez, E. Gomez de Salazar Lopez de Silanes, T. Gramage Caro, T. Bermejo Vicedo Tags: Original Article Source Type: research
An unusual case of acute methotrexate toxicity manifesting as ulcers on psoriatic plaques in an elderly male
Publication date: July 2015 Source:Medical Journal Armed Forces India, Volume 71, Supplement 1 Author(s): G.K. Singh, Manas Chatterjee, Santanu Banerjee, Sourabh Kumar
Source: Medical Journal Armed Forces India - July 28, 2015 Category: Journals (General) Source Type: research
Baricitinib Tops Methotrexate in Early Rheumatoid ArthritisBaricitinib Tops Methotrexate in Early Rheumatoid Arthritis
Baricitinib, alone or in combination with methotrexate, works better than methotrexate alone in patients with early rheumatoid arthritis, according to results from the phase 3 RA-BEGIN trial. Medscape Medical News
Source: Medscape Medical News Headlines - November 9, 2015 Category: Consumer Health News Tags: Rheumatology News Source Type: news
Filgotinib Shows Potential in Rheumatoid ArthritisFilgotinib Shows Potential in Rheumatoid Arthritis
Response to the Janus kinase 1 inhibitor was good in patients with rheumatoid arthritis who have highly active disease despite methotrexate therapy, new research showed. Medscape Medical News
Source: Medscape Medical News Headlines - November 15, 2015 Category: Consumer Health News Tags: Rheumatology News Source Type: news
Too frequent low-dose methotrexate prescriptions: multicentre quality control and quality assurance with pre- and post-analysis.
CONCLUSIONS: The incidences of erroneous too frequent low-dose methotrexate prescriptions observed at both hospitals were considered too high due to the high potential for increased morbidity, mortality and costs. Therefore, quality assurance measures were implemented and the preliminary data show a positive impact on patient safety for both approaches.
PMID: 26599678 [PubMed - in process]
Source: Swiss Medical Weekly - November 27, 2015 Category: Journals (General) Authors: Karlen S, Oertle M, Weiler S, Schneemann M, Eschmann E, Kullak-Ublick GA, Blaser J Tags: Swiss Med Wkly Source Type: research
