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Doxycycline Improves Quality of Life and Anosmia in Chronic Rhinosinusitis With Nasal Polyposis: A Randomized Controlled Trial
CONCLUSION: Doxycycline improves the quality of life in patients with CRSwNP. It also has temporarily beneficial effects in improving the sense of smell. The levels of eosinophil in the blood and nasal secretions do not affect the response to treatment. Hence, doxycycline can be used in both eosinophilic and non-eosinophilic nasal polyps.This study was registered at Iranian Registry of Clinical Trials. https://www.irct.ir/ IRCTID: IRCT20210403050817N1.PMID:36740870 | DOI:10.1177/19458924231154066
Source: American Journal of Rhinology and Allergy - February 6, 2023 Category: ENT & OMF Authors: Mohammad Nabavi Saba Arshi Mohammad Hassan Bemanian Morteza Fallahpour Sima Shokri Sofia Sabouri Fatima Moosavian Javad Nazari Vahid Bakrani Fatemeh Atashrazm Source Type: research

Nanoparticle drug delivery characterization for fluticasone propionate and in vitro testing.
Abstract Glucocorticoids (GCs), such as Fluticasone Propionate (FP), are used for the treatment of inflammation and alleviation of nasal symptoms, allergy, and as anti-pruritic. However, both short and long-term therapeutic use of GCs can lead to muscle weakness and atrophy. In the present study, we evaluated the feasibility of the nano-delivery of FP with polylactic glycolic acid (PLGA) and tested in vitro function. FP-loaded PLGA nanoparticles (NPs) were prepared via nanoprecipitation and morphological characteristics of were studied via scanning electron microscopy. FP-loaded nanoparticles demonstrated an encap...
Source: Canadian Journal of Physiology and Pharmacology - May 16, 2019 Category: Drugs & Pharmacology Authors: Sutariya V, Kelly SJ, Weigel RG, Tur J, Halasz K, Sharma NS, Tipparaju S Tags: Can J Physiol Pharmacol Source Type: research

The impact of targeted therapy in children with uncontrolled allergic persistent severe asthma and nasal polyps
Conclusion: this observation of series cases of severe persistent asthma and concomitant nasal polyps in children, treated with O, showed controversial data about the effect of O on nasal polyposis. Obtained data require further observation
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Vishneva, E., Namazova-Baranova, L., Dobrynina, E., Alekseeva, A., Levina, J., Efendieva, K., Kalugina, V., Selimzianova, L. Tags: Paediatric Asthma and Allergy Source Type: research

4th Pediatric Allergy and Asthma Meeting (PAAM)
DISCUSSION SESSION 1: Food allergy (PD01 –PD05)PD01 Allergen-specific humoral and cellular responses in children who fail egg oral immunotherapy due to allergic reactionsMarta Vazquez-Ortiz, Mariona Pascal, Ana Maria Plaza, Manel JuanPD02 FoxP3 epigenetic features in children with cow milk allergyLorella Paparo, Rita Nocerino, Rosita Aitoro, Ilaria Langella, Antonio Amoroso, Alessia Amoroso, Carmen Di Scala, Roberto Berni CananiPD04 Combined milk and egg allergy in early childhood: let them eat cake?Santanu Maity, Giuseppina Rotiroti, Minal GandhiPD05 Introduction of complementary foods in relation to allergy and gut mic...
Source: Clinical and Translational Allergy - October 31, 2016 Category: Allergy & Immunology Source Type: research

Evaluation of a novel natural drop for treatment of chronic rhinosinusitis without nasal polyps: a single blind randomized trial
ConclusionA P. anisum–based herbal medicine may be an effective treatment for sinusitis without polyps. However, its wide acceptance needs further investigation.
Source: International Forum of Allergy and Rhinology - April 30, 2016 Category: Allergy & Immunology Authors: Shima Vazifehkah, Mohammad Reza Shams‐Ardekani, Mohammad Kamalinejad, Seyed Mousa Saderhossein, Hamed Hosseini, Seyed Mohammad Shams, Shirin Abbassi, Sareh Eghtesad, Babak Saedi Tags: ORIGINAL ARTICLE Source Type: research