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A Rapid Antimicrobial Susceptibility Test for Determining Yersinia pestis Susceptibility to Doxycycline by RT-PCR Quantification of RNA Markers
This study was supported by the Israel Institute for Biological Research, Ness Ziona, Israel. Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Acknowledgments We thank Dr. Vered Caspi (Ben-Gurion University) for assisting with the bioinformatics and statistical analyses of the Agilent DNA microarray results. Supplementary Material The Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fmicb.2019.00754/full#s...
Source: Frontiers in Microbiology - April 15, 2019 Category: Microbiology Source Type: research

Pharmacodynamics of Moxifloxacin, Meropenem, Caspofungin and their Combinations Against In Vitro Polymicrobial Inter-kingdom Biofilms
Antimicrob Agents Chemother. 2021 Dec 20:AAC0214921. doi: 10.1128/AAC.02149-21. Online ahead of print.ABSTRACTBiofilms colonize medical devices and are often recalcitrant to antibiotics. Inter-kingdom biofilms, when at least a bacterium and a fungus are co-isolated, increase the likelihood of therapeutic failures. In this work, a three-species in vitro biofilm model including S. aureus, E. coli and C. albicans was used to study the activity of the antibiotics moxifloxacin and meropenem, the antifungal caspofungin, and combinations of them against inter-kingdom biofilms. The culturable cells and total biomass were evaluated...
Source: Antimicrobial Agents and Chemotherapy - December 21, 2021 Category: Microbiology Authors: Albert Ruiz-Sorribas Herv é Poilvache Fran çoise Van Bambeke Source Type: research

Antimicrobial use at a multi-disciplinary hospital.
CONCLUSIONS: During the analyzed periods we observed some improvement in the sensitivity of the main pathogens to antibiotics. At the same time, the resistance of Acinetobacter baumannii to carbapenems and fluoroquinolones increased.Limitations of the studyThere are many other than antibiotic use factors, which influence these results. Further analysis is planned to be carried out. Nevertheless, this analysis makes us believe that we are, probably, on the right path for improving the use of antibacterial drugs. PMID: 26639689 [PubMed - in process]
Source: International Journal of Risk and Safety in Medicine - December 9, 2015 Category: Drugs & Pharmacology Tags: Int J Risk Saf Med Source Type: research

Determination of in vitro susceptibilities of Brucella spp. strains against 11 different antibacterial gents isolated from blood cultures.
In this study, it was aimed to identify the Brucella strains to the species level isolated from blood cultures, and to determine the rate of antimicrobial susceptibility against eleven antibacterial agents. A total of 106 Brucella spp. strains were included in the study, which were isolated from blood cultures in University of Health Sciences, Konya Training and Research Hospital, Medical Microbiology Laboratory between January 2011 and June 2013. Identification of the isolated strains were mainly based on conventional methods. In vitro antibacterial susceptibilities of azithromycin, ciprofloxacin, doxycycline, gentamicin,...
Source: Mikrobiyoloji Bulteni - September 22, 2017 Category: Microbiology Tags: Mikrobiyol Bul Source Type: research

Delafloxacin (Baxdela) - A New Fluoroquinolone Antibiotic
Date: March 26, 2018 Issue #:  1543Summary:  The FDA has approved delafloxacin (Baxdela– Melinta), an anionic fluoroquinolone antibiotic, for oral and parenteral treatment of adults with acute bacterial skin and skin structure infections (ABSSSIs), including those caused by methicillin-resistantStaphylococcus aureus (MRSA). It is the first fluoroquinolone to be approved for treatment of MRSA.
Source: The Medical Letter - February 21, 2018 Category: Drugs & Pharmacology Authors: admin Tags: Antibacterials Avelox Aztreonam Baxdela Cefazolin Ceftriaxone Cipro Ciprofloxacin Clindamycin delafloxacin Escherichia coli Fluoroquinolones Legionella pneumophila Levofloxacin methicillin-resistant staphylococcus aureus Moxi Source Type: research

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