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Total 408 results found since Jan 2013.

Continuing versus withholding angiotensin receptor blocker (ARB)/calcium channel blocker (CCB) combination tablets during perioperative periods in patients undergoing minor surgery: a single-blinded randomized controlled trial
ConclusionsContinuing ARB/CCB combination tablets preoperatively in patients undergoing minor surgery increased the incidence of hypotension during anesthesia, increased requirements of vasoconstrictors to treat hypotension, and might deteriorate postoperative renal function, albeit slightly. These results suggest that withholding ARB/CCB tablets preoperatively is preferable to continuing them.Clinical trial registrationThis trial is registered with the Japan Registry of Clinical Trials (jRCT) at Japanese Ministry of Health, Labour, and Welfare (Trial ID: jRCT1031190027).
Source: Journal of Anesthesia - March 5, 2022 Category: Anesthesiology Source Type: research

What Affects the Nutritional Quality of Plant-Based Milk Substitutes?
Discussion People today may be eating more plant-based products because of: Allergen avoidance – lactose or cow’s milk allergy, 14% of people with cow’s milk allergy will also have soy allergy. Cultural importance Contamination avoidance e.g. growth hormone or antibiotic residues in cow’s milk production Specific diseases, e.g. cholesterol/lipid issues Environmental impact Ethical or religious considerations Improved nutrition With population growth “[t]he demand for food is expected to grow by 70% until 2050….While the expected protein consumption is believed to grow by 80%.” P...
Source: PediatricEducation.org - September 30, 2019 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Discovery of the regulatory role of calcium ion in muscle contraction and relaxation: Setsuro Ebashi and the international emergence of Japanese muscle research
Adv Physiol Educ. 2022 Jun 27. doi: 10.1152/advan.00108.2022. Online ahead of print.ABSTRACTIn the early 1950s Setsuro Ebashi was a graduate student at Tokyo University studying the biochemical models of muscle contraction. These models contracted in the presence of ATP but what caught his attention was that the models did not relax when ATP was exhausted. Ebashi decided in 1952 to attempt to elucidate the mechanism of muscle relaxation using these models. This decision started a journey that would lead him to be the first to propose the calcium concept of muscle contraction and relaxation in 1961. It was an unpopular theo...
Source: Advances in Physiology Education - June 27, 2022 Category: Physiology Authors: Jack A Rall Source Type: research

Estimating the Prevalence, Clinical Characteristics, and Treatment Patterns of Hypertrophic Cardiomyopathy in Japan: A Nationwide Medical Claims Database Study
CONCLUSIONS: This study provides important information on the current epidemiological and clinical characteristics of HCM in Japan.PMID:36208832 | DOI:10.1016/j.jjcc.2022.09.015
Source: Journal of Cardiology - October 8, 2022 Category: Cardiology Authors: Naoki Terasaka Dionysis Spanopoulos Hidetaka Miyagoshi Toru Kubo Hiroaki Kitaoka Source Type: research

Shockwave Medical Eyes Japan as Next Market for IVL Device
Shockwave Medical is moving to get its Intravascular Lithotripsy (IVL) technology approved in Japan. The Santa Clara-based company said it has initiated the DISRUPT CAD IV study of IVL in heavily calcified coronary arteries. DISRUPT CAD IV is expected to enroll up to 64 patients at eight sites in Japan. Shockwave Medical pointed out the first CAD IV patient was enrolled earlier this week by the principal investigator of the study, Shigeru Saito, MD, Director of Cardiology and Catheterization Laboratories and Vice President, Shonan Kamakura General Hospital. The firm’s device is designed to fracture proble...
Source: MDDI - November 8, 2019 Category: Medical Devices Authors: Omar Ford Tags: Cardiovascular Source Type: news

Immune functions of C ‐type lectins in medical arthropods
This article reviews the current understanding of the structure, function, and signaling pathways involved in CTLs derived from important medical arthropods.
Source: Insect Science - January 20, 2023 Category: Biology Authors: Zhihao Ming, Zhiqiang Chen, Hao Tong, Xia Zhou, Tingting Feng, Dai Jianfeng Tags: REVIEW ARTICLE Source Type: research

In Brief: Pitavastatin Magnesium (Zypitamag) for Hyperlipidemia
Date: June 18, 2018 Issue #:  1549Summary:  The FDA has approved the HMG-CoA reductase inhibitor (statin) pitavastatin magnesium (Zypitamag– Zydus) for use in adults with primary hyperlipidemia or mixed dyslipidemia. The FDA considers pitavastatin magnesium bioequivalent to pitavastatin calcium(Livalo), which was approved in 2009.1Statins remain the treatment of choice for most patients who require lipid-lowering therapy. Taken as an adjunct to diet modification, increased exercise, and smoking cessation, statins can reduce the risk of primary and secondary cardiovascular events and death in ...
Source: The Medical Letter - June 11, 2018 Category: Drugs & Pharmacology Authors: admin Source Type: research