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Specialty: Neurology
Condition: Disability
Education: Study
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Total 3057 results found since Jan 2013.
Monitoring risk and preventing ischemic stroke in the very old
This article examines current guidelines and evidence regarding medical management, lifestyle changes, and psychosocial interactions that can contribute to the primary and secondary prevention of ischemic stroke in the very old.AREAS COVERED: The authors conducted a literature search for ischemic stroke prevention and risk assessment in the elderly via PubMed. Furthermore, they describe current strategies for monitoring risk and preventing ischemic stroke in the elderly population.EXPERT OPINION: Ischemic stroke poses a significant health risk to the elderly, with prevention relying on managing modifiable risk factors such...
Source: Expert Review of Neurotherapeutics - August 4, 2023 Category: Neurology Authors: Mychael Delgardo Grant Rabin Thilan Tudor Anthony J Tang Geoffrey Reeves E Sander Connolly Source Type: research
Age-Associated Resilience Against Ischemic Injury in Mice Exposed to Transient Middle Cerebral Artery Occlusion
AbstractIschemic stroke is the leading cause of death and disability. Although stroke mainly affects aged individuals, animal research is mostly one on young rodents. Here, we examined the development of ischemic injury in young (9 –12-week-old) and adult (72-week-old) C57BL/6 and BALB/c mice exposed to 30 min of intraluminal middle cerebral artery occlusion (MCAo). Post-ischemic reperfusion did not differ between young and adult mice. Ischemic injury assessed by infarct area and blood-brain barrier (BBB) integrity assessed by IgG extravasation analysis was smaller in adult compared with young mice. Microvascular viabili...
Source: Molecular Neurobiology - August 1, 2023 Category: Neurology Source Type: research
A novel digital approach for post-stroke cognitive deficits: a pilot study
CONCLUSIONS: These results suggest that combining digital PA with cognitive training using serious games may be added in clinical settings for cognitive rehabilitation of stroke patients, with beneficial effects extending in promoting independency in activities of daily living and reduction of psychiatric symptoms.PMID:37522228 | DOI:10.3233/RNN-231305
Source: Restorative Neurology and Neuroscience - July 31, 2023 Category: Neurology Authors: Massimiliano Oliveri Sergio Bagnato Silvia Rizzo Emilia Imbornone Andreina Giustiniani Angela Catania Patrizia Turriziani Source Type: research
Burden and attributable risk factors of ischemic stroke in China from 1990 to 2019: an analysis from the Global Burden of Disease Study 2019
ConclusionOur study revealed that great changes have occurred in burden and attributable risk factors of ischemic stroke in China in the past three decades. Distinct sex-specific differences are observed in burden and attributable risk factors.
Source: Frontiers in Neurology - July 26, 2023 Category: Neurology Source Type: research
Long-term behavioural alterations in mice following transient cerebral ischemia
The objective of this study was to clarify whether and to what extent mouse behaviour was altered during a 6 months period after cerebral stroke. Experimental stroke was induced in mice by intraluminal filament insertion into the middle cerebral artery (fMCAo). Neurological deficits, recovery rate, motor performance, and circadian activity were evaluated following ischemia. We observed severe neurological deficits, motor impairments, and delay in the recovery rate of mice during the first 14 days after fMCAo. Aberrant circadian activity and distorted space map were seen in fMCAo mice starting one month after ischemia, simi...
Source: Brain Research - July 22, 2023 Category: Neurology Authors: Zane Dzirkale Vladimirs Pilipenko Barbara Pijet Linda Klimaviciusa Jolanta Upite Karolina Protokowicz Leszek Kaczmarek Baiba Jansone Source Type: research
Recombination of the right cerebral cortex in patients with left side USN after stroke: fNIRS evidence from resting state
ConclusionThe functional network architecture of the right cerebral cortex exhibits significant topological alterations in individuals with USN following stroke, and the sensitivity index based on the small-world property AUC may be utilized to identify these patients accurately.
Source: Frontiers in Neurology - July 20, 2023 Category: Neurology Source Type: research
