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Vaccination: Malaria Vaccine
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Total 36 results found since Jan 2013.
Sporozoite immunization: Innovative Translational Science to Support the Fight against malaria
Expert Rev Vaccines. 2023 Aug 11. doi: 10.1080/14760584.2023.2245890. Online ahead of print.ABSTRACTINTRODUCTION: Malaria, a devastating febrile illness caused by protozoan parasites, sickened 247,000,000 people in 2021 and killed 619,000, mostly children and pregnant women in sub-Saharan Africa. A highly effective vaccine is urgently needed, especially for Plasmodium falciparum (Pf), the deadliest human malaria parasite.AREAS COVERED: Sporozoites (SPZ), the parasite stage transmitted by Anopheles mosquitoes to humans, are the only vaccine immunogen achieving > 90% efficacy against Pf infection. This review describes &g...
Source: Cancer Control - August 12, 2023 Category: Cancer & Oncology Authors: Thomas L Richie L W Preston Church Tooba Murshedkar Peter F Billingsley Eric R James Mei-Chun Chen Yonas Abebe None Natasha Kc Sumana Chakravarty David Dolberg Sara A Healy Halimatou Diawara Mahamadou S Sissoko Issaka Sagara David M Cook Judith E Epstein Source Type: research
Vaccination during pregnancy: A golden opportunity to embrace
Int J Gynaecol Obstet. 2023 Jul 7. doi: 10.1002/ijgo.14981. Online ahead of print.ABSTRACTImmunization strategies are part of routine pregnancy care to prevent infectious diseases in the mother, the fetus, and the newborn. Maternal immunization recommendations followed the recognition of the consequences of infectious diseases in pregnancy, including vertical transmission and perinatal consequences. The recent COVID-19 pandemic highlighted the issue of vaccination among pregnant individuals. Recommendations vary globally; however, Tdap, influenza, and, recently, COVID-19 vaccines are routinely recommended during pregnancy....
Source: Herpes - July 7, 2023 Category: Infectious Diseases Authors: Eliana Amaral Deborah Money Denise Jamieson Dharmintra Pasupathy David Aronoff Bo Jacobsson Edgar Ivan Ortiz Lizcano FIGO Committee on Infections During Pregnancy* Source Type: research
Antenatal interventions to reduce risk of low birth weight related to maternal infections during pregnancy
CONCLUSIONS: At present, there is limited evidence from RCTs available for some potentially relevant interventions targeting maternal infections, which could be prioritized for future research.PMID:37331759 | DOI:10.1016/j.ajcnut.2023.02.025
Source: Am J Clin Nutr - June 18, 2023 Category: Nutrition Authors: Yvonne Muthiani Patricia J Hunter Pieta K N äsänen-Gilmore Annariina M Koivu Jaana Isoj ärvi Juho Luoma Meeri Salenius Maryam Hadji Ulla Ashorn Per Ashorn Source Type: research
Assessment of the quality of antenatal care in Mozambique
CONCLUSIONS: In general, the criteria recommended for quality antenatal care are not incorporated into clinical practice in Mozambique.IMPLICATIONS FOR PRACTICE: While quality antenatal care is essential to reduce maternal morbidity and mortality, many sub-Saharan countries still have low-quality antenatal care services, which is one of the reasons why these countries have the highest maternal mortality rates worldwide.PMID:36706649 | DOI:10.1016/j.midw.2023.103598
Source: Midwifery - January 27, 2023 Category: Midwifery Authors: Belarmina Reis-Muleva Ana Luiza Vilela Borges Luciane Sim ões Duarte Carolina Cavalcante da Silva Dos Santos Nat ália de Castro Nascimento Source Type: research
The battle against malaria in Africa has stalled. Can research in Mozambique explain why?
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Moisés Mapanga, a burly man of 49, is the bait. At 6 p.m. on a mid-April evening, he climbs into an orange tent outside his one-room house in Matutuíne, a hot, swampy district near Maputo, the cap...
Source: Science of Aging Knowledge Environment - September 8, 2022 Category: Geriatrics Source Type: research
Expression of Large Full-Length PfEMP1 Proteins in HEK293 Cells
Methods Mol Biol. 2022;2470:283-298. doi: 10.1007/978-1-0716-2189-9_21.ABSTRACTPlasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is a family of proteins expressed on the surface of red blood cells infected by Plasmodium falciparum. PfEMP1 proteins play a vital role in parasite virulence, and thus are important vaccine candidates to prevent severe disease. VAR2CSA is one specific PfEMP1 essential for pregnancy malaria pathogenesis, and the primary target in pregnancy malaria vaccine development. However, similar to other PfEMP1 proteins, expression of recombinant full-length VAR2CSA is difficult due to its large...
Source: Mol Biol Cell - July 26, 2022 Category: Molecular Biology Authors: Jonathan Paul Renn Justin Yai Alamou Doritchamou Patrick Emmet Duffy Source Type: research
Where is the 'C' in ANC and PNC: a multi-country survey of availability of Antenatal and Postnatal Care in low- and middle-income settings
CONCLUSIONS: Essential components of ANC and PNC are not in place. Focused attention on content is required if perinatal mortality and maternal morbidity during and after pregnancy are to be reduced.PMID:35106907 | DOI:10.1111/1471-0528.17106
Source: BJOG : An International Journal of Obstetrics and Gynaecology - February 2, 2022 Category: OBGYN Authors: Barbara Madaj Somasundari Gopalakrishnan Alexandre Quach Simone Filiaci Adama Traore Dankom Bakusa Mselenge Mdegela Abdul Wali Yousofzai Ahmed Javed Rahmanzai Grace Kodindo Jean-Pierre Gami Njiki Dounou Rostand Hamit Kessely Stephen Ayisi Addo Mercy Abbey Source Type: research
