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Total 26 results found since Jan 2013.

Platelet Count Predicts Adverse Clinical Outcomes After Ischemic Stroke or TIA: Subgroup Analysis of CNSR II
Conclusion: In ischemic stroke or TIA patients with platelet count within normal range, platelet count may be a qualified predictor for long-term recurrent stroke, mortality, and poor functional outcome. Introduction Platelets exert a critical role in the pathogenesis of atherosclerotic complications of cardio-cerebrovascular disease, contributing to thrombus formation, and embolism (1, 2). Previous literature reported that platelets of various size and density are produced by megakaryocytes of different size and stages of maturation in different clinical conditions, suggesting various platelet patterns in differen...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

Hypertensive Disorders in Pregnancy and Future Risk of Stroke: A Systematic Review (P2.114)
CONCLUSIONS: Hypertension in pregnancy likely carries an increased risk for stroke in later life, especially when associated with pre-eclampsia/eclampsia. There may be benefit in targeting these women for close risk-factor monitoring and control beyond the post-partum period.Disclosure: Dr. Ganesh has nothing to disclose. Dr. Sarna has nothing to disclose. Dr. Mehta has nothing to disclose. Dr. Smith has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ganesh, A., Sarna, N., Mehta, R., Smith, E. Tags: Cerebrovascular Disease and Interventional Neurology: Childhood and Young Adult Source Type: research

Women who give birth after 40 'have higher risk of suffering a heart attack or stroke later in life'
A new report presented at the American Stroke Association's International Stroke Conference in LA states that women were more susceptible to stroke following late pregnancy. The Independent
Source: Society for Endocrinology - February 18, 2016 Category: Endocrinology Source Type: news

Study: High blood pressure in mothers during pregnancy raises stroke risk in children
Children with mothers who exhibited high blood pressure during pregnancy show a higher incidence of stroke and heart disease according to a study scheduled for presentation at an online conference this week.
Source: Health News - UPI.com - June 1, 2021 Category: Consumer Health News Source Type: news

FDA Approves Expanded Peripheral Artery Disease (PAD) Indication for XARELTO ® (rivaroxaban) Plus Aspirin to Include Patients After Lower-Extremity Revascularization (LER) Due to Symptomatic PAD
RARITAN, N.J., August 24, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the U.S. Food and Drug Administration (FDA) has approved an expanded peripheral artery disease (PAD) indication for the XARELTO® (rivaroxaban) vascular dose (2.5 mg twice daily plus aspirin 100 mg once daily) to include patients following recent lower-extremity revascularization (LER) due to symptomatic PAD. The approval is based on data from the Phase 3 VOYAGER PAD study. With this approval, XARELTO® is the first and only therapy indicated to help reduce the risks of major cardiovascular (CV) events in p...
Source: Johnson and Johnson - August 24, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Landmark Phase 3 VOYAGER PAD Study of XARELTO ® (rivaroxaban) Plus Aspirin Shows Significant Benefit in Patients with Symptomatic Peripheral Artery Disease (PAD) after Lower-Extremity Revascularization
RARITAN, NJ, March 28, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced the VOYAGER PAD study met its primary efficacy and principal safety endpoints, demonstrating the XARELTO® (rivaroxaban) vascular dose (2.5 mg twice daily) plus aspirin (100 mg once daily) was superior to aspirin alone in reducing the risk of major adverse limb and cardiovascular (CV) events by 15 percent in patients with symptomatic peripheral artery disease (PAD) after lower-extremity revascularization, with similar rates of TIMI[1] major bleeding. VOYAGER PAD is the only study to show a significant benefit using...
Source: Johnson and Johnson - March 28, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

Janssen Submits Application to U.S. FDA for New Indication to Expand Use of XARELTO ® (rivaroxaban) in Patients with Peripheral Artery Disease
RARITAN, NJ, October 26, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today it has submitted a supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration (FDA) for a new indication to expand the use of XARELTO® (rivaroxaban) in patients with peripheral artery disease (PAD). If approved, this new indication for the XARELTO® vascular dose (2.5 mg twice daily plus aspirin 75-100 mg once daily) would include reducing the risk of major thrombotic vascular events such as heart attack, stroke and amputation in patients after recent lower-extremity revascularization, a c...
Source: Johnson and Johnson - October 26, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

E-071 Organization of a Neurointerventional Fellowship Curriculum
The objective of this report is to present a comprehensive three -tier model for a Neurointerventional didactics program. Methods The model divides an annual Neurointerventional didactic curriculum in to three tiers: Introduction to Neurointervention Series: Basic concepts of Neurointervention. Implemented during the first two months of the academic year. Faculty/speaker driven. Total 20 sessions. See Table 1. Neurointervention Core Curriculum: Implemented during months 3 to 12 of the academic year. Faculty/speaker moderated; more interactive. Total 30 sessions. See. Table 2. Neurointervention Advanced Didactics: Period...
Source: Journal of NeuroInterventional Surgery - July 26, 2014 Category: Neurosurgery Authors: Garg, A. Tags: Electronic poster abstracts Source Type: research

Cohort profile: systemic lupus erythematosus in Sweden: the Swedish Lupus Linkage (SLINK) cohort
Purpose A cohort of individuals with systemic lupus erythematosus (SLE) was identified through linkage of several national registers to investigate important epidemiological questions using not only population-based data to minimise selection bias, but also to identify matched comparators from the general population to serve as controls. This cohort was established to overcome the general dearth of data in SLE epidemiology. Participants All individuals registered in Sweden with a personal identity number and who have obtained medical care at any hospital or public non-primary outpatient specialist care with suspected SLE ...
Source: BMJ Open - August 14, 2015 Category: Journals (General) Authors: Arkema, E. V., Simard, J. F. Tags: Open access, Epidemiology, Rheumatology Cohort profile Source Type: research

Title: Beyond Malnutrition: The Role of Sanitation in Stunted Growth
Charles W. Schmidt, MS, an award-winning science writer from Portland, ME, has written for Discover Magazine, Science, and Nature Medicine. Background image: WHO About This Article open Citation: Schmidt CW. 2014. Beyond malnutrition: the role of sanitation in stunted growth. Environ Health Perspect 122:A298–A303; http://dx.doi.org/10.1289/ehp.122-A298 News Topics: Children’s Health, Diet and Nutrition, Gastrointestinal Health, International Environmental Health, Microbial Agents, Musculoskeletal Health, Drinking Water Quality, Sanitation Published: 1 November 2014 PDF Version (2.8 MB) Worldwide, stuntin...
Source: EHP Research - October 31, 2014 Category: Environmental Health Authors: Web Admin Tags: Featured Focus News Children's Health Diet and Nutrition Drinking Water Quality Gastrointestinal Health International Environmental Health Microbial Agents Musculoskeletal Health November 2014 Sanitation Source Type: research

Sex‐ and Gender‐specific Research Priorities for the Emergency Management of Heart Failure and Acute Arrhythmia: Proceedings from the 2014 Academic Emergency Medicine Consensus Conference Cardiovascular Research Workgroup
This article is the result of a breakout session in the cardiovascular and resuscitation work group of the 2014 Academic Emergency Medicine consensus conference “Gender‐Specific Research in Emergency Medicine: Investigate, Understand, and Translate How Gender Affects Patient Outcomes.” A nominal group technique was used to identify and prioritize themes and research questions using electronic mail, monthly conference calls, in‐person meetings, and Web‐based surveys between June 2013 and May 2014. Consensus was achieved through three rounds of nomination followed by the meeting on May 13, 2014, and resulted in sev...
Source: Academic Emergency Medicine - November 24, 2014 Category: Emergency Medicine Authors: Alyson J. McGregor, W. Frank Peacock, Anna Marie Chang, Basmah Safdar, Deborah Diercks Tags: Proceedings Breakout Session Source Type: research

Sex- and Gender-specific Research Priorities for the Emergency Management of Heart Failure and Acute Arrhythmia: Proceedings from the 2014 Academic Emergency Medicine Consensus Conference Cardiovascular Research Workgroup.
This article is the result of a breakout session in the cardiovascular and resuscitation work group of the 2014 Academic Emergency Medicine consensus conference "Gender-Specific Research in Emergency Medicine: Investigate, Understand, and Translate How Gender Affects Patient Outcomes." A nominal group technique was used to identify and prioritize themes and research questions using electronic mail, monthly conference calls, in-person meetings, and Web-based surveys between June 2013 and May 2014. Consensus was achieved through three rounds of nomination followed by the meeting on May 13, 2014, and resulted in seven priorit...
Source: Accident and Emergency Nursing - November 24, 2014 Category: Emergency Medicine Authors: McGregor AJ, Frank Peacock W, Marie Chang A, Safdar B, Diercks D Tags: Acad Emerg Med Source Type: research

Pregnancy Is Scary Enough Without Having To Worry That a Catholic Hospital Might Turn You Away
Maybe I'm just more attuned to it these days -- your 30s will do that to you -- but lately it feels like everyone I know has a scary story about pregnancy. After the adorable photographs have been posted, the celebratory texts sent, the welcome-back-to-the-world-of-sushi-and-beer meals eaten, they tell you about the darker parts of the experience. The nightmarishly long labor. The NICU. The miscarriages that sometimes came before. The last thing any of these women should have to worry about -- the last thing anyone who is pregnant, or their family, should have to worry about -- is being denied appropriate medical care be...
Source: Healthy Living - The Huffington Post - May 9, 2016 Category: Consumer Health News Source Type: news

Abstract B16: Comparing heart age among Alabama residents with and without a history of cancer
Conclusion: Among the sample of 8,153 Alabama residents, cancer survivors have significantly higher heart age score, suggestive of greater risk for developing cardiovascular disease than residents with no history of cancer. Additional analyses will include exploring decision tree and logistic regression models to predict cancer diagnosis. Disparities in race, age, socioeconomic status, and geographic locations will be explored. Future research includes developing interventions to reduce the cardiovascular risk among cancer survivors.Acknowledgments: This study was approved by the University of Alabama at Birmingham Institu...
Source: Cancer Epidemiology Biomarkers and Prevention - February 4, 2017 Category: Cancer & Oncology Authors: Bui, J., Raju, D., Landier, W., Kenzik, K., Scarabelli, T., Meneses, K. Tags: Novel Technologies: Poster Presentations - Proffered Abstracts Source Type: research

Endocrine Disruptors and Health Effects in Africa: A Call for Action
Conclusion: To address the many challenges posed by EDCs, we argue that Africans should take the lead in prioritization and evaluation of environmental hazards, including EDCs. We recommend the institution of education and training programs for chemical users, adoption of the precautionary principle, establishment of biomonitoring programs, and funding of community-based epidemiology and wildlife research programs led and funded by African institutes and private companies. https://doi.org/10.1289/EHP1774 Received: 16 February 2017 Revised: 22 May 2017 Accepted: 24 May 2017 Published: 22 August 2017 Address correspond...
Source: EHP Research - August 23, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Commentary Source Type: research