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Condition: Atrial Fibrillation
Nutrition: Calcium
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Total 97 results found since Jan 2013.
Estimating the Prevalence, Clinical Characteristics, and Treatment Patterns of Hypertrophic Cardiomyopathy in Japan: A Nationwide Medical Claims Database Study
CONCLUSIONS: This study provides important information on the current epidemiological and clinical characteristics of HCM in Japan.PMID:36208832 | DOI:10.1016/j.jjcc.2022.09.015
Source: Journal of Cardiology - October 8, 2022 Category: Cardiology Authors: Naoki Terasaka Dionysis Spanopoulos Hidetaka Miyagoshi Toru Kubo Hiroaki Kitaoka Source Type: research
Calcium signalling microdomains and the t-tubular system in atrial mycoytes: potential roles in cardiac disease and arrhythmias
The atria contribute 25% to ventricular stroke volume and are the site of the commonest cardiac arrhythmia, atrial fibrillation (AF). The initiation of contraction in the atria is similar to that in the ventricle involving a systolic rise of intracellular Ca2+ concentration ([Ca2+]i). There are, however, substantial inter-species differences in the way systolic Ca2+ is regulated in atrial cells. These differences are a consequence of a well-developed and functionally relevant transverse (t)-tubule network in the atria of large mammals, including humans, and its virtual absence in smaller laboratory species such as the rat....
Source: Cardiovascular Research - April 23, 2013 Category: Cardiology Authors: Trafford, A. W., Clarke, J. D., Richards, M. A., Eisner, D. A., Dibb, K. M. Tags: SPOTLIGHT REVIEWS: SPOTLIGHT ON T-TUBULES AND RYANODINE RECEPTOR MICRODOMAIN SIGNALLING IN CARDIAC HYPERTROPHY AND FAILURE Source Type: research
MicroRNAs emerging as mediators of remodeling with atrial fibrillation
Atrial fibrillation (AF) is the most common cardiac arrhythmia and is now established as an independent risk factor for stroke. Moreover, a concomitant diagnosis of AF greatly complicates treatment for a number of disease processes such as diabetes and congestive heart failure. Given the recognized additional burden that AF places on the health-care system, significant research has been performed in an attempt to delineate mechanisms that contribute to AF initiation as well as progression. Understandably, there is an extensive body of research that has identified abnormalities in ionic channels/electrogenic processes that ...
Source: Heart Rhythm - March 25, 2013 Category: Cardiology Authors: Adam W. Akerman, Rupak Mukherjee Tags: Editorial Commentary Source Type: research
Characterization of a novel multi‐functional resveratrol derivative for the treatment of atrial fibrillation.
Conclusion and ImplicationsThese findings indicate that C1 is a promising multi‐functional small molecule that targets a number of key pathways involved in AF.
Source: British Journal of Pharmacology - September 17, 2013 Category: Drugs & Pharmacology Authors: Istvan Baczko, David Liknes, Wei Yang, Kevin C Hamming, Gavin Searle, Kristian Jaeger, Zoltan Husti, Viktor Juhasz, Gergely Klausz, Robert Pap, Laszlo Saghy, Andras Varro, Vernon Dolinsky, Shaohua Wang, Vivek Rauniyar, Dennis Hall, Jason R. Dyck, Peter E. Tags: Research Paper Source Type: research
Characterization of a novel multifunctional resveratrol derivative for the treatment of atrial fibrillation
Conclusion and ImplicationsC1 behaved as a promising multifunctional small molecule targeting a number of key pathways involved in AF.
Source: British Journal of Pharmacology - December 10, 2013 Category: Drugs & Pharmacology Authors: Istvan Baczko, David Liknes, Wei Yang, Kevin C Hamming, Gavin Searle, Kristian Jaeger, Zoltan Husti, Viktor Juhasz, Gergely Klausz, Robert Pap, Laszlo Saghy, Andras Varro, Vernon Dolinsky, Shaohua Wang, Vivek Rauniyar, Dennis Hall, Jason RB Dyck, Peter E Tags: RESEARCH PAPER Source Type: research
Statins do not improve cardiovascular outcomes for dialysis patients
Commentary on: Palmer SC, Navaneethan SD, Craig JC, et al.. HMG CoA reductase inhibitors (statins) for dialysis patients: a systematic review and meta-analysis. Cochrane Database Syst Rev 2013;(9):CD004289. Context Chronic kidney disease affected nearly 19 million people in the USA, with incidence increasing globally at an annual rate of 8%, most of which were unrecognised or undiagnosed. Cardiovascular events are common among patients with chronic kidney disease and highest in dialysis patients. While dialysis patients experience a high prevalence of traditional risk factors for cardiovascular disease (CVD), such as hyper...
Source: Evidence-Based Medicine - May 19, 2014 Category: Internal Medicine Authors: Olyaei, A. Tags: Clinical trials (epidemiology), Epidemiologic studies, Drugs: cardiovascular system, Neuromuscular disease, Stroke, Hypertension, Obesity (nutrition), Ischaemic heart disease, Unwanted effects / adverse reactions, Renal medicine, Musculoskeletal syndromes Source Type: research
P-119 * different measures to prevent atrial fibrillation in patients undergoing pulmonary resection for lung cancer: evidence from a comprehensive network meta-analysis of randomized and observational studies
Conclusions: Beta-blockers and flecainide are effective in reducing the incidence of postoperative AF in patients after pulmonary resections which is not the case with digoxin; data on remaining treatments are sparse and preclude drawing definite conclusions.
Disclosure: No significant relationships.
Source: Interactive CardioVascular and Thoracic Surgery - June 9, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Kowalewski, M., Lewandowska, M. A., Kowalewski, J. Tags: SESSION VII: MODERATED POSTERS Source Type: research
Coronary Artery Calcium and Risk of Atrial Fibrillation (From the Multi-Ethnic Study of Atherosclerosis)
Calcified coronary arteries are associated with the development of cardiovascular disease and stroke. It is currently unknown whether coronary artery calcium (CAC) is associated with an increased risk of atrial fibrillation (AF). We addressed this question in 6,641 participants (mean age 62 ± 10; 53% women; 62% non-whites) from the Multi-Ethnic Study of Atherosclerosis (MESA) who were free of baseline clinical cardiovascular disease and AF. CAC measurements were assessed by cardiac computed tomography (CT) at study baseline.
Source: The American Journal of Cardiology - September 14, 2014 Category: Cardiology Authors: Wesley T. O’Neal, Jimmy T. Efird, Farah Z. Dawood, Joseph Yeboah, Alvaro Alonso, Susan R. Heckbert, Elsayed Z. Soliman Source Type: research
Comparative Persistence on β-Blockers Versus Calcium Channel Blockers for Ventricular Rate Control in Nonelderly Patients With Atrial Fibrillation.
CONCLUSIONS: Evidence suggests that nonelderly AF patients, when prescribed rate-control therapy, persist longer on BBs than CCBs. Because this is the first long-term study comparing the 2 drug classes in the nonelderly population, further research is suggested.
PMID: 25280975 [PubMed - as supplied by publisher]
Source: The Annals of Pharmacotherapy - October 3, 2014 Category: Drugs & Pharmacology Authors: Desai VC, Kelton CM, Metzger AH, Cavanaugh TM, Guo JJ, Heaton PC Tags: Ann Pharmacother Source Type: research
Affinity Proteomics for Phosphatase Interactions in Atrial Fibrillation ∗
Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice, with an estimated 30 million individuals affected worldwide (1). AF constitutes a major risk factor for stroke and heart failure, resulting in significant morbidity and mortality. Remodeling of the atria is a consequence as well as a substrate for perpetuation of AF. The remodeling process occurs at various levels, including atrial fibrosis, cardiomyocyte contractibility, and electrical coupling. During electrical remodeling, an unbalanced calcium (Ca2+) transport exposes cardiomyocytes locally to increased Ca2+ levels. Ca2+ overload i...
Source: Journal of the American College of Cardiology - January 12, 2015 Category: Cardiology Source Type: research
Vitamin D deficiency and atrial fibrillation
Vitamin D deficiency has been linked with hypertension, coronary artery disease, and stroke, but there is no consensus regarding the possible association between vitamin D deficiency and atrial fibrillation (AF). Vitamin D negatively regulates the renin–angiotensin–aldosterone-system (RAAS), mediates calcium homeostasis, binds to vitamin D receptors on cardiac myocytes, and has antioxidant properties that may reduce levels of reactive oxygen species (ROS) in the atria, which contribute to inflammation and proarrhythmic substrate formation.
Source: International Journal of Cardiology - February 10, 2015 Category: Cardiology Authors: Joseph Thompson, Rynda Nitiahpapand, Prashan Bhatti, Antonios Kourliouros Tags: Review Source Type: research
Atrial fibrillation: effects beyond the atrium?
Atrial fibrillation (AF) is the most common sustained clinical arrhythmia and is associated with significant morbidity, mostly secondary to heart failure and stroke, and an estimated two-fold increase in premature death. Efforts to increase our understanding of AF and its complications have focused on unravelling the mechanisms of electrical and structural remodelling of the atrial myocardium. Yet, it is increasingly recognized that AF is more than an atrial disease, being associated with systemic inflammation, endothelial dysfunction, and adverse effects on the structure and function of the left ventricular myocardium tha...
Source: Cardiovascular Research - February 23, 2015 Category: Cardiology Authors: Wijesurendra, R. S., Casadei, B. Tags: REVIEW Source Type: research
