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Condition: Atrial Fibrillation
Countries: Japan Health

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Total 333 results found since Jan 2013.

Clinical Outcomes of Off-Label Underdosing of Direct Oral Anticoagulants After Ablation for Atrial Fibrillation.
In conclusion, the clinical adverse event rates for patients on an off-label under-dose DOAC regimen after ablation, predicated on careful patient evaluations, was not high as seen with that of patients on a standard DOAC dosing regimen. PMID: 33191353 [PubMed - as supplied by publisher]
Source: International Heart Journal - November 17, 2020 Category: Cardiology Tags: Int Heart J Source Type: research

A Comparative Prospective Observational Study on the Use of Direct Oral Anticoagulants after Cardiac Surgery for the Management of Atrial Fibrillation.
CONCLUSION: DOAC as anticoagulation therapy for the early intervention of POAF following cardiac surgery is associated with a low incidence of major bleeding; a favorable safety profile and excellent efficacy were demonstrated for DOAC. Furthermore, our results indicate that the safety and efficacy of apixaban and edoxaban are better than rivaroxaban. PMID: 33208579 [PubMed - as supplied by publisher]
Source: Annals of Thoracic and Cardiovascular Surgery - November 18, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Sezai A, Taoka M, Osaka S, Kitazumi Y, Suzuki K, Kamata K, Tanaka M Tags: Ann Thorac Cardiovasc Surg Source Type: research

Impact of Frailty on Bleeding Events Related to Anticoagulation Therapy in Patients With Atrial Fibrillation.
CONCLUSIONS: Frailty is associated with increased bleeding events related to anticoagulant therapy in patients previously hospitalized with AF. Greater care should be taken with patients with a CHS frailty index ≥2. PMID: 33504742 [PubMed - as supplied by publisher]
Source: Circulation Journal - January 27, 2021 Category: Cardiology Authors: Ohta M, Hayashi K, Mori Y, Sato H, Noto T, Kawahatsu K, Mita T, Kazuno Y, Sasaki S, Doi T, Hirokami M, Tanaka S, Yuda S Tags: Circ J Source Type: research

Metabolically Healthy Obesity and the Risk of Cardiovascular Disease in the General Population 　- Analysis of a Nationwide Epidemiological Database.
CONCLUSIONS: Among individuals with no metabolic disorders, MHO alone did not significantly increase the subsequent CVD risk. However, individuals with comorbid MHO and abdominal obesity had a higher risk of myocardial infarction, angina pectoris, heart failure, and atrial fibrillation, suggesting the prognostic importance of abdominal obesity in subjects with MHO. PMID: 33551397 [PubMed - as supplied by publisher]
Source: Circulation Journal - February 5, 2021 Category: Cardiology Authors: Itoh H, Kaneko H, Kiriyama H, Kamon T, Fujiu K, Morita K, Michihata N, Jo T, Takeda N, Morita H, Yasunaga H, Komuro I Tags: Circ J Source Type: research

Major adverse cardiovascular events and mortality after catheter ablation in Japanese patients with atrial fibrillation: The Fushimi AF Registry
ConclusionCA was associated with lower incidences of MACE and all-cause mortality for patients with AF as compared with those who received drug therapy. The most common event of MACE in patients who underwent CA was heart failure hospitalization.Clinical trial registrationURL:http://www.umin.ac.jp/ctr/index.htmUnique identifierUMIN000005834.
Source: Heart and Vessels - February 11, 2021 Category: Cardiology Source Type: research

Serum High-Sensitivity C-Reactive Protein Levels and the Development of Atrial Fibrillation in a General Japanese Population 　- The Hisayama Study.
CONCLUSIONS: The study findings suggest that elevated serum hs-CRP levels are an independent risk factor for the development of AF in a general Japanese population. PMID: 33597325 [PubMed - as supplied by publisher]
Source: Circulation Journal - February 18, 2021 Category: Cardiology Authors: Yoshikawa T, Hata J, Sakata S, Nagata T, Hirakawa Y, Hirooka Y, Tsutsui H, Kitazono T, Ninomiya T Tags: Circ J Source Type: research

Serum High-Sensitivity C-Reactive Protein Levels and the Development of Atrial Fibrillation in a General Japanese Population 　- The Hisayama Study
CONCLUSIONS: The study findings suggest that elevated serum hs-CRP levels are an independent risk factor for the development of AF in a general Japanese population.PMID:33597325 | DOI:10.1253/circj.CJ-20-0751
Source: Circulation Journal - February 18, 2021 Category: Cardiology Authors: Tomoko Yoshikawa Jun Hata Satoko Sakata Takuya Nagata Yoichiro Hirakawa Yoshitaka Hirooka Hiroyuki Tsutsui Takanari Kitazono Toshiharu Ninomiya Source Type: research

Current status of oral anticoagulant adherence in Japanese patients with atrial fibrillation: A claims database analysis
CONCLUSION: In a real-world Japanese claim data analysis, about 70% of patients under DOAC showed persistence with anticoagulation therapy at 3 years. High adherence to DOACs assessed by PDC (over 90%) persisted to 3 years regardless of the types of DOACs.PMID:33663881 | DOI:10.1016/j.jjcc.2021.02.007
Source: Journal of Cardiology - March 5, 2021 Category: Cardiology Authors: Naoharu Yagi Shinya Suzuki Katsuhiko Nagai Takashi Tanaka Takayoshi Nagahama Takuto Arita Takayuki Otsuka Takeshi Yamashita Source Type: research

Different Determinants of the Recurrence of Atrial Fibrillation and Adverse Clinical Events in the Mid-Term Period After Atrial Fibrillation Ablation
CONCLUSIONS: This study disclosed different determinants of post-ablation recurrence and AEs. Female sex, persistent AF, and enlarged LAd were determinants of post-ablation recurrence, whereas an old age, comorbidities, and LV and renal dysfunction rather than post-ablation recurrence were AEs determinants. These findings will help determine ablation indications and post-ablation management.PMID:34219078 | DOI:10.1253/circj.CJ-21-0326
Source: Circulation Journal - July 5, 2021 Category: Cardiology Authors: Ryuta Watanabe Koichi Nagashima Yuji Wakamatsu Naoto Otsuka Katsuaki Yokoyama Naoya Matsumoto Takayuki Otsuka Shinya Suzuki Akio Hirata Masato Murakami Mitsuru Takami Masaomi Kimura Hidehira Fukaya Shiro Nakahara Takeshi Kato Hiroshi Hayashi Yu-Ki Iwasaki Source Type: research

Clinical significance of new ‐onset atrial fibrillation in patients with hypertrophic cardiomyopathy
ConclusionsIn our HCM registry in an aged Japanese community, a significant proportion developed AF. The presence of AF, particularly new-onset AF, was associated with increased incidence of HCM-related events. AF may not be just a marker of disease stage but an important trigger of adverse events.
Source: ESC Heart Failure - September 2, 2021 Category: Cardiology Authors: Toru Kubo, Yuichi Baba, Yuri Ochi, Takayoshi Hirota, Naohito Yamasaki, Kazuya Kawai, Katsuhito Yamamoto, Fumiaki Kondo, Kanji Bando, Eisuke Yamada, Takashi Furuno, Toshikazu Yabe, Yoshinori L. Doi, Hiroaki Kitaoka Tags: Original Research Article Source Type: research

Characteristics and clinical outcomes in atrial fibrillation patients classified using cluster analysis: the Fushimi AF Registry
ConclusionsWe identified six clinically relevant phenotypes of AF patients on cluster analysis. These phenotypes can be associated with various types of comorbidities and associated with the incidence of clinical outcomes.Clinical Trial Registration Informationhttps://www.umin.ac.jp/ctr/index.htm. Unique identifier: UMIN000005834.
Source: Europace - April 30, 2021 Category: Cardiology Source Type: research