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Surgical vs transfemoral aortic valve replacement in low ‐risk patients: An updated meta‐analysis of trial and registry data
ConclusionsEarly mortality is higher in SAVR while rates of PVL and PPMI are substantially higher in TAVR. There is no significant advantage with TAVR for overall survival, cardiovascular death, stroke, MI, and re ‐intervention rates.
Source: Journal of Cardiac Surgery - July 10, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Suvitesh Luthra, Miguel M. Leiva ‐Juárez, Sunil K. Ohri Tags: ORIGINAL ARTICLE Source Type: research

Bicuspid Aortic Insufficiency With Aortic Root Aneurysm: Root Reimplantation Versus Bentall Root Replacement.
CONCLUSIONS: In patients with bicuspid aortic valve AI with root aneurysm, primary cusp repair with root reimplantation achieves equivalent midterm outcomes compared with Bentall root replacement. PMID: 27261086 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - May 31, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Vallabhajosyula P, Szeto WY, Habertheuer A, Komlo C, Milewski RK, McCarthy F, Desai ND, Bavaria JE Tags: Ann Thorac Surg Source Type: research

Bicuspid Aortic Insufficiency With Aortic Root Aneurysm: Root Reimplantation Versus Bentall Root Replacement
Conclusions In patients with bicuspid aortic valve AI with root aneurysm, primary cusp repair with root reimplantation achieves equivalent midterm outcomes compared with Bentall root replacement.
Source: The Annals of Thoracic Surgery - September 18, 2016 Category: Cardiovascular & Thoracic Surgery Source Type: research

Direct oral anticoagulant use in nonvalvular atrial fibrillation with valvular heart disease: a systematic review
In conclusion, subanalyses of DOAC landmark AF trials revealed that dabigatran, rivaroxaban, and apixaban may be safely used in AF patients with certain types of VHD: aortic stenosis, aortic regurgitation, and mitral regurgitation. More evidence is needed before routinely recommending these agents for patients with bioprosthetic valves or mild mitral stenosis. Patients with moderate to severe mitral stenosis or mechanical valves should continue to receive warfarin, as these patients were excluded from all landmark AF trials.
Source: Clinical Cardiology - December 21, 2016 Category: Cardiology Authors: Ryan E. Owens, Rajesh Kabra, Carrie S. Oliphant Tags: Reviews Source Type: research

Survival and Stroke Similar for TAVR and SAVR at 5 Years Survival and Stroke Similar for TAVR and SAVR at 5 Years
The early mortality benefit seen with transcatheter aortic valve replacement over surgical repair in patients with severe aortic stenosis at high surgical risk is no longer significant at 5 years.Medscape Medical News
Source: Medscape Medical News Headlines - November 26, 2018 Category: Consumer Health News Tags: Cardiology News Source Type: news

The German Aortic Valve Registry (GARY): in-hospital outcome
Conclusion The in-hospital outcome results of this registry show that conventional surgery yields excellent results in all risk groups and that catheter-based aortic valve replacements is an alternative to conventional surgery in high risk and elderly patients.
Source: European Heart Journal - June 21, 2014 Category: Cardiology Authors: Hamm, C. W., Mollmann, H., Holzhey, D., Beckmann, A., Veit, C., Figulla, H.-R., Cremer, J., Kuck, K.-H., Lange, R., Zahn, R., Sack, S., Schuler, G., Walther, T., Beyersdorf, F., Bohm, M., Heusch, G., Funkat, A.-K., Meinertz, T., Neumann, T., Papoutsis, K. Tags: FASTTRACK CLINICAL Source Type: research

067-I * TREATMENT OF AORTIC VALVE STENOSIS: FIVE YEARS OF EXPERIENCE WITH AN INTEGRATED 360{degrees} APPROACH IN A HIGH-VOLUME CENTRE
Conclusion: The "One Heart–One Team" approach, offering all treatment strategies, techniques and devices, allows a tailor-made, patient-orientated surgery and is of utmost importance for offering an individualised treatment option for almost every patient in almost every risk constellation.
Source: Interactive CardioVascular and Thoracic Surgery - September 23, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Wilbring, M., Taut, T., Ibrahim, K., Matschke, K., Kappert, U. Tags: Adult cardiac rapid response 1 Source Type: research

How to define valvular atrial fibrillation?
Abstract Atrial fibrillation (AF) confers a substantial risk of stroke. Recent trials comparing vitamin K antagonists (VKAs) with non-vitamin K antagonist oral anticoagulants (NOACs) in AF were performed among patients with so-called "non-valvular" AF. The distinction between "valvular" and "non-valvular" AF remains a matter of debate. Currently, "valvular AF" refers to patients with mitral stenosis or artificial heart valves (and valve repair in North American guidelines only), and should be treated with VKAs. Valvular heart diseases, such as mitral regurgitation, aortic stenosis (AS) and aortic insufficiency, do...
Source: Archives of Cardiovascular Diseases - July 13, 2015 Category: Cardiology Authors: Fauchier L, Philippart R, Clementy N, Bourguignon T, Angoulvant D, Ivanes F, Babuty D, Bernard A Tags: Arch Cardiovasc Dis Source Type: research

Aortic valve repair in the paediatric population: insights from a 38-year single-centre experience CONGENITAL
CONCLUSIONS In our experience, AV repair in the paediatric population provides excellent results in terms of both overall survival and valve-related reoperation. It obviates the need for chronic anticoagulation and in most cases delays the time at which more complex surgery such as the Ross procedure should be undertaken.
Source: European Journal of Cardio-Thoracic Surgery - January 10, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Poncelet, A. J., El Khoury, G., De Kerchove, L., Sluysmans, T., Moniotte, S., Momeni, M., Detaille, T., Rubay, J. E. Tags: Basic research vascular CONGENITAL Source Type: research

Assistive technology using regurgitation fraction and fractional-order integration to assess pulmonary valve insufficiency for pre-surgery decision making and post-surgery outcome evaluation
This study proposes an assistive technology to quantify regurgitation using the regurgitation fraction (RF) and heart pump efficiency (HPE). In signal preprocessing stage, the detrending and zero-crossing processes are used to remove the unwanted flow fluctuations and identify the end-systolic and end-diastolic periods per each cardiac cycle. The fractional-order integrations are employed to calculate the stroke volume (SV) and regurgitation volume (RV). Then, the regurgitation flow can be quantified that indicates the high correlation with HPE. For a mimicking pulmonary circulation loop system, the proposed screening mode...
Source: Biomedical Signal Processing and Control - June 1, 2018 Category: Biomedical Science Source Type: research

Current status and future perspective of structural heart disease intervention.
Abstract Valvular heart diseases are one of the most frequent causes for heart failure. Degenerative diseases of the aortic and mitral valve as well as a dysfunctional tricuspid valve disease result in a worse clinical outcome if severe. Minimal-invasive, surgical and/or catheter-based structural heart disease (SHD) interventions have recently seen a dramatic increase. Transcatheter aortic valve implantation (TAVI) for severe aortic stenosis (AS) is a disruptive technology, and next generation devices and careful patient selection will minimize limitations of TAVI such as paravalvular leak, conductance disturbance...
Source: Journal of Cardiology - April 3, 2019 Category: Cardiology Authors: Tabata N, Sinning JM, Kaikita K, Tsujita K, Nickenig G, Werner N Tags: J Cardiol Source Type: research

Spontaneous Spinal Epidural Hematoma in an Adult Patient with Complex Congenital Heart Disease
We report the case of a 27-year-old man who developed sudden upper back pain with no specific precipitant. Five days later, he visited our emergency department complaining of weakness in both lower limbs and dysuria. He had a history of intracardiac repair and a Blalock-Park procedure for an interrupted aortic arch and ventricular septal defect in infancy. Additionally, he had undergone an aortic root dilatation and aortic valve replacement at the age of 10 because of progression of aortic and supra-aortic stenosis and had received chronic anticoagulation and antiplatelet therapy with warfarin and aspirin, respectively. An...
Source: International Heart Journal - July 8, 2021 Category: Cardiology Authors: Toshinobu Ifuku Toshihiro Nishiguchi Source Type: research

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