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Pure Thalamic Infarct: 8-Year Follow-Up Study in a Hospital in China
In conclusion, our cohort of pure thalamic infarcts were mainly due to SVO (TOAST), with hypertension as the main risk factor, and the inferolateral artery as the most implicated arterial territory. Less severe outcome or stroke recurrence are identified in long-term follow-up of pure thalamic infarcts. Other comorbidities would be cause of death in aged patients.
Source: Frontiers in Neurology - September 14, 2021 Category: Neurology Source Type: research

Stroke Dysbiosis Index (SDI) in Gut Microbiome Are Associated With Brain Injury and Prognosis of Stroke
Conclusions: We developed an index to measure gut microbiota dysbiosis in stroke patients; this index was significantly correlated with patients' outcome and was causally related to outcome in a mouse model of stroke. Our model facilitates the potential clinical application of gut microbiota data in stroke and adds quantitative evidence linking the gut microbiota to stroke. Introduction Ischemic stroke imposes a heavy burden on society, with 24.9 million cases worldwide (1). Although intravenous thrombolysis and endovascular treatment greatly improve some patients' prognosis, the prognosis for most pa...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Internal Carotid Artery Occlusion Causing Acute Cranial Neuropathies
A 54-year-old male with a history of left posterior parietal ischemic stroke, epilepsy, tobacco and marijuana smoking, and alcohol abuse, presented with acute left visual loss and diplopia. On examination, he had reduced left visual acuity and a left oculomotor nerve palsy. CT angiogram from aortic arch to circle of Willis identified extensive thrombus occluding the left common and internal carotid arteries, extending to the left ophthalmic artery. This case demonstrates acute visual loss from ophthalmic artery occlusion, and left oculomotor nerve palsy from occlusion of the inferolateral trunk of the internal carotid arte...
Source: Journal of Stroke and Cerebrovascular Diseases - January 9, 2019 Category: Neurology Authors: Stephen R. Duma, Samer Ghattas, Florence C.F. Chang Tags: Case Report Source Type: research

Retinal and Ophthalmic Artery Studies in Ischemic Stroke Patients Using Fundus Photography and Transcranial Doppler Methods (P4.252)
Conclusions:Our study in a robust sample of non-severe stroke patients showed that abnormal retinal AVR is strongly associated with IS patients even after accounting for traditional risk factors. OA-TCD studies, on the other hand, did not have significant associations with stroke group.Disclosure: Dr. Patil has nothing to disclose. Dr. Narayan has nothing to disclose. Dr. Babu K has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Patil, K., Narayan, S., Babu, K. R. Tags: Acute and Diagnostic Imaging in Ischemic Stroke and TIA Source Type: research

Man-in-the-barrel syndrome with Delayed Diffusion-weighted MRI Findings (P3.072)
Conclusions:DWI has a high degree of sensitivity and specificity. Nevertheless, false negative results often occur because of small infarct size, early imaging, and brainstem locations. The rate of false negative results with DWI has been estimated to be 17%. We argue it may be advisable to repeat MRI in certain cases were stroke is highly suspected up to 72 hours post symptoms. Often false negative DWI occur in posterior circulation strokes making our case unique, given it is in the anterior circulation. One possible explanation for this, is differences in cerebral reserve between a young patient versus an older patient d...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Magun, R., Ching, M., Sawyer, R., Mowla, A. Tags: Cerebrovascular Disease and Interventional Neurology ePoster Session Source Type: research

Posterior hippocampal stroke presenting with transient global amnesia.
We describe a patient with presenting symptoms of TGA, but affected by an ischemic hippocampal stroke. The computed tomography angiography helped the etiologic diagnosis showing an hemodynamic stenosis of the posterior P2P segment. Interestingly, neuropsychological features were consistent with those found in patients suffering TGA. PMID: 28004602 [PubMed - as supplied by publisher]
Source: Neurocase - December 21, 2016 Category: Neurology Authors: Naldi F, Baiardi S, Guarino M, Spinardi L, Cirignotta F, Stracciari A Tags: Neurocase Source Type: research

Risk Factors Associated With the Presence of Unruptured Intracranial Aneurysms Clinical Sciences
Conclusions— The risk factors for UIAs differ by their location, compared with the control. Interestingly, the presence of coronary artery disease was protective against the presence of UIAs.
Source: Stroke - October 26, 2015 Category: Neurology Authors: Kang, H. G., Kim, B. J., Lee, J., Kim, M.-J., Kang, D.-W., Kim, J. S., Kwon, S. U. Tags: Cerebral Aneurysm, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage Clinical Sciences Source Type: research

An Unusual Cause Of Recurrent Ischemic Stroke: Trousseau's Syndrome From Gastric Cancer (P4.231)
CONCLUSIONS: Trousseau’s Syndrome must be considered in those presenting with recurrent strokes with an otherwise negative embolic work up especially in the elderly and those with cancer risk factors. It must prompt the clinician to look for an associated malignancy.Disclosure: Dr. JADEJA has nothing to disclose. Dr. Johnson has nothing to disclose. Dr. Soetanto has nothing to disclose. Dr. Nalleballe has nothing to disclose. Dr. DeNiro has nothing to disclose. Dr. Qureshi has nothing to disclose. Dr. Graber has received personal compensation for activities with Stemedica Inc., Novocure Inc., and Biogen Idec.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Jadeja, N., Johnson, J., Soetanto, A., Nalleballe, K., DeNiro, L., Qureshi, I., Graber, J. Tags: Neuro-oncology: Paraneoplastic Disorders Source Type: research

Bilateral ascending weakness in a patient with Azygous Anterior Cerebral Artery Stroke. (P1.040)
CONCLUSION: Our patient’s clinical presentation was challenging because ascending pattern of weakness is usually seen in Acute Inflammatory Demyleinating Neuropathy or spinal cord injury. During the early stages deep tendon reflexes may be perserved in many conditions but may change on serial clinical examination. Hyperreflexia noted on follow-up examination and the absence of sensory involvemnt were the key feature suggesting a cerebral insult. Our study calls to attention to this rare vascular anomaly and its misleading clinical presentation.Disclosure: Dr. Melkumova has nothing to disclose. Dr. Noroozi has nothing...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Melkumova, E., Noroozi, J., Zisman, C., Sahni, R. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

Early Clinical Signs, Lesion Localization, and Prognostic Factors in Unilateral Symptomatic Internal Carotid Artery Occlusion
Conclusions: In unilateral symptomatic intracranial carotid artery occlusion, poor prognosis and high mortality–associated territorial stroke pattern is frequently observed. Besides, presence of severe stenosis or occlusion and absence of collateral circulation in MCA are associated with poor prognosis.
Source: Journal of Stroke and Cerebrovascular Diseases - April 18, 2014 Category: Neurology Authors: Sibel Güler, Ufuk Utku, Özer Aynaci Tags: Original Articles Source Type: research

Geographic and Sex Difference in the Distribution of Intracranial Atherosclerosis in China Clinical Sciences
Conclusions— There exists geographic and sex difference in the distribution of symptomatic ICAS in China. Public health measures should strengthen improving social determinants of health and risk factor prevention/control in high-risk populations for decreasing stroke risk.
Source: Stroke - July 22, 2013 Category: Neurology Authors: Pu, Y., Liu, L., Wang, Y., Zou, X., Pan, Y., Soo, Y., Leung, T., Zhao, X., Wong, K. S., Wang, Y., on behalf of the Chinese IntraCranial AtheroSclerosis (CICAS) Study Group Tags: Risk Factors, Acute Cerebral Infarction Clinical Sciences Source Type: research