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Specialty: Research
Condition: Thrombosis
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Total 312 results found since Jan 2013.
Effects of low molecular weight heparin combined with hyperbaric oxygen on neurologic function and coagulation factors in patients with intracranial venous thrombosis
CONCLUSIONS: LMWH combined with HBO can effectively improve the clinical efficacy and neurologic function of patients with ICVT and reduce the levels of coagulation factors and inflammatory factors.PMID:35422938 | PMC:PMC8991144
Source: American Journal of Translational Research - April 15, 2022 Category: Research Authors: Bo-Feng Liu Xiao-Hui Liu Xiao-Hui Dong Ning Ma Hui-Ping Zhang Li-Li Jiang Yan-Qing Liu Source Type: research
A Review of the Role of the Antiplatelet Drug Ticagrelor in the Management of Acute Coronary Syndrome, Acute Thrombotic Disease, and Other Diseases
Med Sci Monit. 2022 May 16;28:e935664. doi: 10.12659/MSM.935664.ABSTRACTP2Y12 inhibitors, including aspirin, are key components of dual-antiplatelet therapy (DAPT), which is the optimal therapeutic strategy for preventing arterial thrombosis in patients with acute coronary syndromes (ACS) who underwent stent implantation. Ticagrelor is a cyclopentyl-triazole pyrimidine antiplatelet drug that was the first reversible oral P2Y12 receptor antagonist. Compared with clopidogrel, ticagrelor exerts a faster onset and offset of function by reversible and selective inhibition of platelet aggregation in ACS patients, including those...
Source: Medical Science Monitor - May 16, 2022 Category: Research Authors: Luyuan Tao Shijia Ren Li Zhang Wenhua Liu Yi Zhao Changgong Chen Xiang Mao Zili Chen Xingjian Gu Source Type: research
Double-Gene Copromoting Expression Analysis in tPA/GH Transgenic Goat Mammary Epithelial Cells and Thrombolytic Activity of tPA In Vitro
This study provided a new way for the preparation of a transgenic goat and other animal with high tPA expression by somatic cell nuclear transfer. The findings also laid a foundation for efficient production of pharmaceutical proteins in transgenic animal mammary gland bioreactors in the future.PMID:35572725 | PMC:PMC9106445 | DOI:10.1155/2022/6484073
Source: Biomed Res - May 16, 2022 Category: Research Authors: Shaozheng Song Yaoling Luo Zhaoxia Liu Dan Li Junsong Ye ZhengYi He Source Type: research
A Review of the Role of the Antiplatelet Drug Ticagrelor in the Management of Acute Coronary Syndrome, Acute Thrombotic Disease, and Other Diseases
Med Sci Monit. 2022 May 16;28:e935664. doi: 10.12659/MSM.935664.ABSTRACTP2Y12 inhibitors, including aspirin, are key components of dual-antiplatelet therapy (DAPT), which is the optimal therapeutic strategy for preventing arterial thrombosis in patients with acute coronary syndromes (ACS) who underwent stent implantation. Ticagrelor is a cyclopentyl-triazole pyrimidine antiplatelet drug that was the first reversible oral P2Y12 receptor antagonist. Compared with clopidogrel, ticagrelor exerts a faster onset and offset of function by reversible and selective inhibition of platelet aggregation in ACS patients, including those...
Source: Medical Science Monitor - May 16, 2022 Category: Research Authors: Luyuan Tao Shijia Ren Li Zhang Wenhua Liu Yi Zhao Changgong Chen Xiang Mao Zili Chen Xingjian Gu Source Type: research
Double-Gene Copromoting Expression Analysis in tPA/GH Transgenic Goat Mammary Epithelial Cells and Thrombolytic Activity of tPA In Vitro
This study provided a new way for the preparation of a transgenic goat and other animal with high tPA expression by somatic cell nuclear transfer. The findings also laid a foundation for efficient production of pharmaceutical proteins in transgenic animal mammary gland bioreactors in the future.PMID:35572725 | PMC:PMC9106445 | DOI:10.1155/2022/6484073
Source: Biomed Res - May 16, 2022 Category: Research Authors: Shaozheng Song Yaoling Luo Zhaoxia Liu Dan Li Junsong Ye ZhengYi He Source Type: research
High-sensitivity C-reactive protein as a better predictor of post-thrombolytic functional outcome in patients with previous antiplatelet therapy
ConclusionshsCRP is correlated with the clinical outcome of patients treated with IVrt-PA, and may be a better predictor of post-thrombolytic functional outcome in patients with previous antiplatelet therapy than in non-used patients.
Source: European Journal of Medical Research - June 3, 2022 Category: Research Source Type: research
A Cohort Study on the Safety and Efficacy of Warfarin and Rivaroxaban in Anticoagulant Therapy in Patients with Atrial Fibrillation Study
CONCLUSION: Compared with warfarin, rivaroxaban anticoagulant therapy has the same advantage in tolerance and prevention of thromboembolism in patients with AF, but rivaroxaban can effectively reduce the risk of bleeding in patients with AF.PMID:35845939 | PMC:PMC9283039 | DOI:10.1155/2022/4611383
Source: Biomed Res - July 18, 2022 Category: Research Authors: Li Wang Wentao Yao Source Type: research
Pharmacological Effect of < em > Panax notoginseng < /em > Saponins on Cerebral Ischemia in Animal Models
In conclusion, PNS showed antagonistic effects on ischemic stroke, and pharmacological mechanisms are likely to be associated with the reduction of cerebral pathological damage, thrombolysis, antihypoxia, and improvement in the intracellular Ca2+ overload and cerebral energy metabolism.PMID:35968235 | PMC:PMC9371884 | DOI:10.1155/2022/4281483
Source: Biomed Res - August 15, 2022 Category: Research Authors: Chao Dong Jiawei Li Ming Zhao Lin Chen Xiaochen Zhai Lingling Song Jin Zhao Qiang Sun Jie Wu Xiaolu Xie Source Type: research
Impact of apixaban treatment discontinuation on the risk of hospitalization among patients with nonvalvular atrial fibrillation and COVID-19
CONCLUSION: NVAF patients with COVID-19 who discontinued apixaban had a higher risk of hospitalization and thrombotic events vs. those who continued apixaban, with no significant difference in bleeding-related hospitalization.PMID:36000258 | DOI:10.1080/03007995.2022.2112871
Source: Current Medical Research and Opinion - August 24, 2022 Category: Research Authors: Steven Deitelzweig Julia Zhu Jenny Jiang Xuemei Luo Allison Keshishian Mauricio Ferri Lisa Rosenblatt Patricia Schuler Cynthia Gutierrez Amol D Dhamane Source Type: research
