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Condition: Stroke
Procedure: PET Scan

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Total 6091 results found since Jan 2013.

Effects of blood pressure lowering in patients with acute ischemic stroke and carotid artery stenosis
ConclusionsThere is no clear evidence that the effect of candesartan is qualitatively different in patients with carotid artery stenosis, but there are signals that patients with severe stenosis are at particularly high risk of stroke progression and poor functional outcome.
Source: International Journal of Stroke - December 3, 2014 Category: Neurology Authors: Mirza Jusufovic, Else Charlotte Sandset, Philip M. W. Bath, Björn W. Karlson, Eivind Berge, Tags: Research Source Type: research

Misery Perfusion, Blood Pressure Control, and 5-Year Stroke Risk in Symptomatic Major Cerebral Artery Disease Brief Reports
Conclusion— Patients with MP showed a high-5-year stroke recurrence, but a large part of the 5-year stroke risk disappeared after 2 years. Aggressive BP control may be hazardous in patients with impaired perfusion, including MP.
Source: Stroke - December 22, 2014 Category: Neurology Authors: Yamauchi, H., Kagawa, S., Kishibe, Y., Takahashi, M., Higashi, T. Tags: Other diagnostic testing Brief Reports Source Type: research

Effects of candesartan in acute stroke on vascular events during long‐term follow‐up: results from the Scandinavian Candesartan Acute Stroke Trial (SCAST)
ConclusionsTreatment with candesartan in the acute phase of stroke was not associated with clear long‐term clinical benefits. This result supports the conclusion from trials with short‐term follow‐up, that blood pressure lowering treatment with candesartan should not be given routinely to patients with acute stroke and raised blood pressure.
Source: International Journal of Stroke - March 23, 2015 Category: Neurology Authors: Astrid G. Hornslien, Else C. Sandset, Jannicke Igland, Andreas Terént, Gudrun Boysen, Philip M. W. Bath, Gordon D. Murray, Eivind Berge Tags: Research Source Type: research

Does Emergency department length of stay affect the 90-day functional outcome after acute ischemic stroke? (P3.073)
Conclusion: In our cohort, there was no association between the ED-LOS and 90-day functional outcome. Further study is ongoing to assess whether ED-LOS adversely affects outcome measures not captured by the mRS.Disclosure: Dr. Patel has nothing to disclose. Dr. Minaeian has nothing to disclose. Dr. Tunguturi has nothing to disclose. Dr. Goddeau has nothing to disclose. Dr. Henninger has received personal compensation in an editorial capacity for Stroke.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Patel, A., Minaeian, A., Tunguturi, A., Goddeau, R., Henninger, N. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Outcome Source Type: research

Abstract 101: A Learning Collaborative Model to Improve Door to Needle Time for Stroke Thrombolysis in Chicago Session Title: Abstract Poster Session I and Reception
Conclusions: Using a learning collaborative model to implement strategies to reduce DTN times among 15 PSCs in Chicago, we observed major improvements within a few months. Regional collaboration and best practices sharing should be a model for rapid and sustainable system-wide quality improvement.
Source: Circulation: Cardiovascular Quality and Outcomes - February 26, 2016 Category: Cardiology Authors: Prabhakaran, S., ONeill, K., Chicago Primary Stroke Cntrs Tags: Session Title: Abstract Poster Session I and Reception Source Type: research

Prevalence of Amyloid Positron Emission Tomographic Positivity in Poststroke Mild Cognitive Impairment Brief Reports
Conclusions— The prevalence of amyloid-pathology in patients with PS-MCI is not increased when compared with cognitively healthy stroke survivors and to recent estimates for cognitively healthy elderly subjects. Factors other than amyloid-pathology likely contribute to the development of PS-MCI. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01334749.
Source: Stroke - September 25, 2016 Category: Neurology Authors: Wollenweber, F. A., Darr, S., Muller, C., Duering, M., Buerger, K., Zietemann, V., Malik, R., Brendel, M., Ertl-Wagner, B., Bartenstein, P., Rominger, A., Dichgans, M. Tags: Magnetic Resonance Imaging (MRI), Nuclear Cardiology and PET, Cerebrovascular Disease/Stroke, Cognitive Impairment Brief Reports Source Type: research

DCE-MRI blood-brain barrier assessment in acute ischemic stroke
Conclusion: BBB in acute stroke patients can be successfully assessed quantitatively. The decrease of BBB permeability in unaffected regions at follow-up may be an indicator of global BBB leakage even in vessel territories remote from the index infarct.
Source: Neurology - January 29, 2017 Category: Neurology Authors: Villringer, K., Sanz Cuesta, B. E., Ostwaldt, A.-C., Grittner, U., Brunecker, P., Khalil, A. A., Schindler, K., Eisenblätter, O., Audebert, H., Fiebach, J. B. Tags: Diagnostic test assessment, MRI, All Cerebrovascular disease/Stroke ARTICLE Source Type: research

Target Stroke Implementation: Best Practice Strategies Cut Thrombolysis Time to < 30 minutes in a 1,550 Bed Academic Urban County Hospital (P4.280)
Conclusions:Individualized hospital gap analysis identifies targeted interventions to shorten treatment times. DTN and DTG time can be reduced with implementation of simple, low-cost interventions, with persistent effect and no increase in symptomatic intracranial hemorrhage or stroke mimic treatment.Disclosure: Dr. Marulanda-Londoño has nothing to disclose. Dr. Bhatt has nothing to disclose. Dr. Atchaneeyasakul has nothing to disclose. Dr. Asdaghi has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Akram has nothing to disclose. Dr. Zhang has nothing to disclose. Dr. D’Amour has nothing to disclos...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Marulanda-Londono, E., Bhatt, N., Atchaneeyasakul, K., Asdaghi, N., Malik, A., Akram, N., Zhang, T., DAmour, D., Hesse, K., Sacco, R., Romano, J. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Pre-existing Small Vessel Disease in Patients with Acute Stroke from the Middle East, Southeast Asia, and Philippines
AbstractAsymptomatic small vessel disease (SVD), including white matter hyperintensities (WMHIs), periventricular hyperintensities (PVHIs), silent stroke (SS), and cerebral microbleeds (CMBs), increases the risk of stroke. There are limited studies of SVD in subjects from the Middle East and Southeast Asia (SA). All patients admitted to stroke service between 2014 and 2015 were reviewed for presence of “pre-existing” SVD. Stroke mimics with no previous history of stroke were used as controls. There were 1727 patients admitted with stroke. Analysis was done on 988 subjects (914 strokes and 74 controls) who had MRI scan ...
Source: Translational Stroke Research - November 3, 2017 Category: Neurology Source Type: research

Bouncing back: Nolan ’s life after stroke
Although he’s only a little over a year old, Nolan Morel is a bona fide charmer. Clad in a red shirt and navy blue suspenders, he flashes a happy grin at his mother, Rosalia; his physician, Dr. Laura Lehman; and the others in the room. “Look at those dimples!” someone coos, and he giggles in response. “I can’t believe how social he’s being,” laughs Rosalia. “He wasn’t always like this.” In fact, Nolan’s first several days of life were anything but lighthearted. Just a few hours after his birth at a hospital north of Boston, he stopped breathing and had to be manually resuscitated and given oxygen. Whe...
Source: Thrive, Children's Hospital Boston - December 7, 2017 Category: Pediatrics Authors: Jessica Cerretani Tags: Diseases & Conditions Our Patients’ Stories child life Dr. Laura Lehman feeding therapy occupational therapy physical therapy stroke Stroke and Cerebrovascular Center Source Type: news

Processes of early stroke care and hospital costs
ConclusionsEarly care in agreement with key guidelines recommendations for the management of patients with stroke may be associated with hospital savings.
Source: International Journal of Stroke - December 19, 2013 Category: Neurology Authors: Marie Louise Svendsen, Lars H. Ehlers, Heidi H. Hundborg, Annette Ingeman, Søren P. Johnsen Tags: Research Source Type: research

Pooled Assessment of Computed Tomography Interpretation by Vascular Neurologists in the STRokE DOC Telestroke Network
Conclusions: Both vascular neurologists and reports from spoke radiologists had excellent reliability in identifying radiologic rt-PA contraindications. These pooled findings demonstrate that telestroke evaluation of head CT scans for acute rt-PA assessments is reliable.
Source: Journal of Stroke and Cerebrovascular Diseases - May 21, 2013 Category: Neurology Authors: Ilana Spokoyny, Rema Raman, Karin Ernstrom, Bart M. Demaerschalk, Patrick D. Lyden, Thomas M. Hemmen, Amy K. Guzik, James Y. Chen, Brett C. Meyer Tags: Original Articles Source Type: research

Significance of Periclot MMP-9 in Ischemic Stroke Patients Undergoing Intra-arterial Interventions (P4.303)
CONCLUSIONS: Decreased periclot MMP-9 may be predictive of HT after ischemic stroke, contrasting with previous work demonstrating elevated peripheral MMP-9 as predictive of HT. Increased periclot MCP-4 and angiogenin expression, as well as decreased numbers of circulating monocytes, may serve as additional predictive markers of HT. Future work should measure the activity of periclot MMP-9. Study Supported by: Shimojani, LLC and NIH (DJ).Disclosure: Dr. Song has nothing to disclose. Dr. Prager has nothing to disclose. Dr. Brennan has nothing to disclose. Dr. Uchino has nothing to disclose. Dr. Hussain has nothing to disclos...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Song, A., Prager, B., Brennan, C., Uchino, K., Hussain, M., Rasmussen, P., Janigro, D. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Interventional Treatment for Ischemic Stroke Source Type: research

Diagnostic delays in paediatric stroke
Conclusions The diagnosis of AIS in children is delayed at every stage of the pathway but most profoundly when the first neuroimaging is CT scanning, which is non-diagnostic. MRI should be the initial imaging modality of choice in any suspected case of childhood AIS.
Source: Journal of Neurology, Neurosurgery and Psychiatry - July 14, 2015 Category: Neurosurgery Authors: Mallick, A. A., Ganesan, V., Kirkham, F. J., Fallon, P., Hedderly, T., McShane, T., Parker, A. P., Wassmer, E., Wraige, E., Amin, S., Edwards, H. B., O'Callaghan, F. J. Tags: Coma and raised intracranial pressure, Stroke, Radiology, Radiology (diagnostics) Cerebrovascular disease Source Type: research

The role of hippocampal pathology in post-stroke cognitive impairment
Background Cognitive impairment is common following cerebrovascular disease. Recently it has been associated with hippocampal ultra-structural damage in stroke survivors. We aim to study the long-term cognitive profile of patients after ischaemic stroke and characterise the cognitive behaviours associated with any dynamic changes in the structure, function and metabolism of the hippocampi, using multimodal MRI at 3Tesla. Methods We are conducting a dual-centre study to investigate the predictive value of diagnostic MRI and resting-state fMRI based on observing natural history of cognitive function following stroke (at bas...
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 14, 2016 Category: Neurosurgery Authors: Hosseini, A. A., Ispoglou, S., Hayton, T., Evans, R., Wilson, M., Sawlani, V., Rotshtein, P., Auer, D. P. Tags: Stroke, Memory disorders (psychiatry), Radiology, Radiology (diagnostics) ABN Annual Meeting, 17-19 May 2016, The Brighton Centre, Brighton Source Type: research