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Specialty: Cardiology
Condition: Stroke

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Total 25838 results found since Jan 2013.

Statins and the risks of stroke recurrence and death after ischemic stroke: The Fukuoka Stroke Registry
This study aimed to elucidate whether prescribed doses of statins reduce the risks of cerebrovascular events (CVEs: stroke recurrence or transient ischemic attack) and all-cause mortality in a cohort of Japanese patients with first-ever ischemic stroke.Methods: The 2822 eligible patients registered in the Fukuoka Stroke Registry with first-ever acute ischemic stroke from June 2007 to February 2011 were classified into statin users (n = 993) and non-users (n = 1829) at discharge, and followed up until March 2012. We assessed the cumulative risks of CVE and all-cause mortality by the Kaplan–Meier method, and calculated...
Source: Atherosclerosis - November 25, 2013 Category: Cardiology Authors: Noriko Makihara, Masahiro Kamouchi, Jun Hata, Ryu Matsuo, Tetsuro Ago, Junya Kuroda, Takahiro Kuwashiro, Hiroshi Sugimori, Takanari Kitazono, Fukuoka Stroke Registry Investigators Tags: Clinical & Population Research – Intervention Source Type: research

High Blood Pressure After Acute Ischemic Stroke Is Associated With Poor Clinical Outcomes: Fukuoka Stroke Registry Stroke and Blood Pressure
The relationship between the poststroke blood pressure (BP) and functional outcomes in patients with acute ischemic stroke is still controversial. The aim of the present study was to elucidate the impact of the poststroke BP on the clinical outcomes of acute ischemic stroke. Among the patients in the Fukuoka Stroke Registry, 1874 patients with first-ever acute ischemic stroke (within 24 hours of onset) who had been functionally independent before onset were prospectively enrolled in the present study. The poststroke BP levels were defined as the average values during the 48 hours after onset. The study outcomes were a good...
Source: Hypertension - December 11, 2013 Category: Cardiology Authors: Ishitsuka, K., Kamouchi, M., Hata, J., Fukuda, K., Matsuo, R., Kuroda, J., Ago, T., Kuwashiro, T., Sugimori, H., Nakane, H., Kitazono, T., on behalf of the FSR Investigators Tags: Stroke and Blood Pressure Source Type: research

Large artery stiffness and carotid flow pulsatility in stroke survivors
Objective:Aortic stiffness is increased in lacunar stroke. The precise mechanism linking aortic stiffness to symptomatic lacunar stroke is not well understood. The aim of this study was to compare the effects of aortic stiffness, carotid stiffness, central blood pressure, and cerebrovascular resistance on carotid flow pulsatility according to stroke subtype. Methods:Two hundred and one consecutive patients were examined 13 months after hospitalization for their first-ever ischemic stroke. The stroke subtype was classified using the Causative Classification of Stroke System. Carotid–femoral pulse wave velocity (PWV) was u...
Source: Journal of Hypertension - April 7, 2014 Category: Cardiology Tags: ORIGINAL PAPERS: Stroke Source Type: research

Abstract 7: Risk of Intracranial Hemorrhage Among Acute Ischemic Stroke Patients Receiving Prior Antiplatelet Therapy and Treated with Intravenous Tissue Plasminogen Activator Session Title: Concurrent I Session B: Oral Abstracts on Stroke Topics
Conclusion: This study represents the largest clinical experience of the safety of thrombolysis in patients on prior antiplatelet therapy. Despite a higher incidence of sICH, the absolute excess risk appears small (0.67%). These findings support current guideline recommendations regarding use of intravenous tPA in patients on antiplatelet therapy with careful weighing of potential risk and benefit.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Xian, Y., Grau-Spulveda, M., Schwamm, L. H., Bhatt, D. L., Smith, E. E., Reeves, M. J., Federspiel, J., Thomas, L., Bettger, J. P., Laskowitz, D. T., Hernandez, A. F., Fonarow, G. C., Peterson, E. D. Tags: Session Title: Concurrent I Session B: Oral Abstracts on Stroke Topics Source Type: research

Comparative Effectiveness of Standard Care With IV Thrombolysis Versus Without IV Thrombolysis for Mild Ischemic Stroke Stroke
Conclusions In this observational registry-based study, standard care with IVT is more effective than not receiving IVT in mild ischemic stroke patients, and there is a statistically nonsignificant risk of symptomatic hemorrhagic transformation.
Source: JAHA:Journal of the American Heart Association - January 9, 2015 Category: Cardiology Authors: Choi, J. C., Jang, M. U., Kang, K., Park, J.-M., Ko, Y., Lee, S.-J., Cha, J.-K., Kim, D.-H., Park, S. S., Park, T. H., Lee, K. B., Lee, J., Kim, J.-T., Cho, K.-H., Yu, K.-H., Oh, M.-S., Lee, B.-C., Cho, Y.-J., Kim, D.-E., Lee, J. S., Lee, J., Gorelick, P. Tags: Stroke Source Type: research

Abstract 106: Defining an International Standard Set of Patient-centered Outcome Measures After Stroke Session Title: Poster Session I
Conclusions: The stroke measure Standard Set is proposed for implementation to permit meaningful comparisons and increase value of stroke care worldwide using a simple, pragmatic strategy.
Source: Circulation: Cardiovascular Quality and Outcomes - April 29, 2015 Category: Cardiology Authors: Salinas, J., ICHOM Stroke Measure Group Tags: Session Title: Poster Session I Source Type: research

Ethnic Differences in Associations Between Blood Pressure and Stroke in South Asian and European Men Epidemiology/Population
We report findings from a UK cohort study of 1375 European and 1074 South Asian men, not receiving antihypertensive medication, aged 40 to 69 years at baseline (1988–1991). Assessment included BP, blood tests, anthropometry, and questionnaires. Incident stroke was established at 20 years from death certification, hospital and primary care records, and participant report. South Asians had higher systolic BP, diastolic BP, and mean arterial pressure than Europeans, and similar pulse pressure. Associations between systolic BP or diastolic BP and stroke were stronger in South Asians than Europeans, after adjustment for a...
Source: Hypertension - August 12, 2015 Category: Cardiology Authors: Eastwood, S. V., Tillin, T., Chaturvedi, N., Hughes, A. D. Tags: Cerebrovascular disease/stroke, Risk Factors, Epidemiology Epidemiology/Population Source Type: research

Variation and Trends in the Documentation of National Institutes of Health Stroke Scale in GWTG-Stroke Hospitals Original Articles
Conclusions— Documentation of NIHSS is higher in patients who are thrombolysis candidates. Evidence of modest bias in NIHSS scores was observed but this has lessened as the documentation of NIHSS has improved in recent years.
Source: Circulation: Cardiovascular Quality and Outcomes - October 29, 2015 Category: Cardiology Authors: Reeves, M. J., Smith, E. E., Fonarow, G. C., Zhao, X., Thompson, M., Peterson, E. D., Schwamm, L. H., Olson, D. Tags: Cerebrovascular Disease/Stroke Original Articles Source Type: research

Care Trajectories of Veterans in the 12 Months After Hospitalization for Acute Ischemic Stroke Original Articles
Conclusions— Care trajectories after stroke were associated with stroke severity and functional dependency and they had a dramatic impact on subsequent costs.
Source: Circulation: Cardiovascular Quality and Outcomes - October 29, 2015 Category: Cardiology Authors: Arling, G., Ofner, S., Reeves, M. J., Myers, L. J., Williams, L. S., Daggy, J. K., Phipps, M. S., Chumbler, N., Bravata, D. M. Tags: Ethics and Policy, Cerebrovascular Disease/Stroke Original Articles Source Type: research

Chronic Stroke Outcome Measures for Motor Function Intervention Trials: Expert Panel Recommendations Original Articles
Conclusions— The panel recommends that the Fugl-Meyer Upper and Lower Extremity scales be used as primary outcomes in intervention trials targeting motor function in populations with chronic stroke. The other 6 measures are recommended as secondary outcomes.
Source: Circulation: Cardiovascular Quality and Outcomes - October 29, 2015 Category: Cardiology Authors: Bushnell, C., Bettger, J. P., Cockroft, K. M., Cramer, S. C., Edelen, M. O., Hanley, D., Katzan, I. L., Mattke, S., Nilsen, D. M., Piquado, T., Skidmore, E. R., Wing, K., Yenokyan, G. Tags: Behavioral/Psychosocial Treatment, Quality and Outcomes, Ischemic Stroke Original Articles Source Type: research

Dysbiosis of Gut Microbiota With Reduced Trimethylamine-N-Oxide Level in Patients With Large-Artery Atherosclerotic Stroke or Transient Ischemic Attack Stroke
Conclusions Participants with asymptomatic atherosclerosis did not exhibit an obvious change in gut microbiota and blood TMAO levels; however, stroke and transient ischemic attack patients showed significant dysbiosis of the gut microbiota, and their blood TMAO levels were decreased.
Source: JAHA:Journal of the American Heart Association - November 23, 2015 Category: Cardiology Authors: Yin, J., Liao, S.-X., He, Y., Wang, S., Xia, G.-H., Liu, F.-T., Zhu, J.-J., You, C., Chen, Q., Zhou, L., Pan, S.-Y., Zhou, H.-W. Tags: Stroke Source Type: research

Abstract 101: A Learning Collaborative Model to Improve Door to Needle Time for Stroke Thrombolysis in Chicago Session Title: Abstract Poster Session I and Reception
Conclusions: Using a learning collaborative model to implement strategies to reduce DTN times among 15 PSCs in Chicago, we observed major improvements within a few months. Regional collaboration and best practices sharing should be a model for rapid and sustainable system-wide quality improvement.
Source: Circulation: Cardiovascular Quality and Outcomes - February 26, 2016 Category: Cardiology Authors: Prabhakaran, S., ONeill, K., Chicago Primary Stroke Cntrs Tags: Session Title: Abstract Poster Session I and Reception Source Type: research

Quantifying Selection Bias in National Institute of Health Stroke Scale Data Documented in an Acute Stroke Registry Original Articles
Conclusions— We demonstrate modest, but important, selection bias in documented NIHSS data, which are missing more often in patients with less severe stroke. The population mean NIHSS score was overestimated by >2 points, which could significantly alter the risk profile of hospitals treating patients with ischemic stroke and subsequent hospital risk–adjusted outcomes.
Source: Circulation: Cardiovascular Quality and Outcomes - May 16, 2016 Category: Cardiology Authors: Thompson, M. P., Luo, Z., Gardiner, J., Burke, J. F., Nickles, A., Reeves, M. J. Tags: Ischemic Stroke Original Articles Source Type: research

Prehospital Phase of the Stroke Chain of Survival: A Prospective Observational Study Stroke
Conclusions Fast emergency medical services activation and ambulance transport promoted early hospital arrival and treatment. Although patient-dependent delays still dominate the prehospital process, it should be ensured that the minutes on the scene are well spent.
Source: JAHA:Journal of the American Heart Association - May 1, 2016 Category: Cardiology Authors: Puolakka, T., Strbian, D., Harve, H., Kuisma, M., Lindsberg, P. J. Tags: Stroke Source Type: research

Impact of Increased Early Statin Administration on Ischemic Stroke Outcomes: A Multicenter Electronic Medical Record Intervention Stroke
Conclusions A simple EMR change increased early statin administration in ischemic stroke and was associated with improved clinical outcomes. This is, to our knowledge, the first EMR intervention study to show that a modification of an electronic order set resulted in improved clinical outcomes.
Source: JAHA:Journal of the American Heart Association - July 28, 2016 Category: Cardiology Authors: Flint, A. C., Conell, C., Klingman, J. G., Rao, V. A., Chan, S. L., Kamel, H., Cullen, S. P., Faigeles, B. S., Sidney, S., Johnston, S. C. Tags: Ischemic Stroke, Neuroprotectants Source Type: research