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Condition: Stroke
Procedure: MRI Scan

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Total 6681 results found since Jan 2013.

The Clinical Relevance of Microbleeds in Stroke study (CROMIS‐2): rationale, design, and methods
Background and rationaleThe increasing use of oral anticoagulants, mostly to prevent ischemic stroke due to atrial fibrillation in an ageing population, has been associated with a fivefold increased incidence of oral anticoagulant‐associated intracerebral hemorrhage: a rare, serious, and unpredictable complication. We hypothesize that cerebral microbleeds and other markers of cerebral small vessel disease on magnetic resonance imaging, and genetic polymorphisms (e.g. influencing cerebral small vessel integrity or anticoagulation stability), are associated with an increased risk of oral anticoagulant‐associated intracer...
Source: International Journal of Stroke - August 2, 2015 Category: Neurology Authors: Andreas Charidimou, Duncan Wilson, Clare Shakeshaft, Gareth Ambler, Mark White, Hannah Cohen, Tarek Yousry, Rustam Al‐Shahi Salman, Gregory Lip, Henry Houlden, Hans R. Jäger, Martin M. Brown, David J. Werring Tags: Protocol Source Type: research

Comparison of the 2 Most Popular Deconvolution Techniques for the Detection of Penumbral Flow in Acute Stroke Clinical Sciences
Conclusions— Block-circulant single value decomposition seems only significantly beneficial for mean transit time maps in (sub)acute stroke. Tmax is likely the most stable deconvolved parameter for the detection of tissue-at-risk using DSC-MRI.
Source: Stroke - September 28, 2015 Category: Neurology Authors: Zaro-Weber, O., Livne, M., Martin, S. Z., von Samson-Himmelstjerna, F. C., Moeller-Hartmann, W., Schuster, A., Brunecker, P., Heiss, W.-D., Sobesky, J., Madai, V. I. Tags: Acute Cerebral Infarction, Computerized tomography and Magnetic Resonance Imaging, PET and SPECT Clinical Sciences Source Type: research

Infarct Volume Prediction by Early Magnetic Resonance Imaging in a Murine Stroke Model Depends on Ischemia Duration and Time of Imaging Basic Sciences
Conclusions— The prediction accuracy of early magnetic resonance imaging for infarct volumes depends on timing of magnetic resonance imaging and MCAO duration. Variability of the posterior communicating artery in C57Bl6 mice contributes to differences in prediction accuracy between short and long MCAO. Early ADC imaging may be used to reduce errors in the interpretation of post MCAO treatment effects on stroke volumes.
Source: Stroke - October 26, 2015 Category: Neurology Authors: Leithner, C., Fuchtemeier, M., Jorks, D., Mueller, S., Dirnagl, U., Royl, G. Tags: Animal models of human disease, Acute Cerebral Infarction, Brain Circulation and Metabolism, Computerized tomography and Magnetic Resonance Imaging Basic Sciences Source Type: research

Intra-Arterial Therapy and Post-Treatment Infarct Volumes: Insights From the ESCAPE Randomized Controlled Trial Clinical Sciences
Conclusions— These results support the primary results of the ESCAPE trial and show that the biological underpinning of the success of endovascular therapy is a reduction in infarct volume. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01778335.
Source: Stroke - February 22, 2016 Category: Neurology Authors: Al-Ajlan, F. S., Goyal, M., Demchuk, A. M., Minhas, P., Sabiq, F., Assis, Z., Willinsky, R., Montanera, W. J., Rempel, J. L., Shuaib, A., Thornton, J., Williams, D., Roy, D., Poppe, A. Y., Jovin, T. G., Sapkota, B. L., Baxter, B. W., Krings, T., Silver, F Tags: Imaging, Quality and Outcomes, Ischemic Stroke Clinical Sciences Source Type: research

Early Fiber Number Ratio Is a Surrogate of Corticospinal Tract Integrity and Predicts Motor Recovery After Stroke Clinical Sciences
Conclusions— Early measurement of FNr at 24 to 72 hours poststroke is a surrogate marker of corticospinal tract integrity and provides independent prediction of motor outcome at 1 year especially for patients with severe initial impairment.
Source: Stroke - March 27, 2016 Category: Neurology Authors: Bigourdan, A., Munsch, F., Coupe, P., Guttmann, C. R. G., Sagnier, S., Renou, P., Debruxelles, S., Poli, M., Dousset, V., Sibon, I., Tourdias, T. Tags: Magnetic Resonance Imaging (MRI), Prognosis Clinical Sciences Source Type: research

An Approach to Working Up Cases of Embolic Stroke of Undetermined Source Stroke
Conclusions Our data indicate that patients with cryptogenic embolic stroke show distinct clinical and radiological features depending on the underlying causes.
Source: JAHA:Journal of the American Heart Association - March 21, 2016 Category: Cardiology Authors: Ryoo, S., Chung, J.-W., Lee, M. J., Kim, S. J., Lee, J. S., Kim, G.-M., Chung, C.-S., Lee, K. H., Hong, J. M., Bang, O. Y. Tags: Etiology, Risk Factors, Magnetic Resonance Imaging (MRI), Ischemic Stroke Source Type: research

Association of Ideal Cardiovascular Health With Vascular Brain Injury and Incident Dementia Clinical Sciences
Conclusions— Adherence to the American Heart Association’s ideal CVH factors and behaviors, particularly in midlife, may protect against cerebrovascular disease and dementia.
Source: Stroke - April 24, 2016 Category: Neurology Authors: Pase, M. P., Beiser, A., Enserro, D., Xanthakis, V., Aparicio, H., Satizabal, C. L., Himali, J. J., Kase, C. S., Vasan, R. S., DeCarli, C., Seshadri, S. Tags: Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke, Cognitive Impairment Clinical Sciences Source Type: research

Pathogenesis and Risk Factors for Cerebral Infarct After Surgical Aortic Valve Replacement Brief Reports
Conclusions— The principal mechanism of acute cerebral infarction after aortic valve replacement is embolism. There are distinct factors associated with watershed and embolic infarct, some of which may be modifiable.
Source: Stroke - July 24, 2016 Category: Neurology Authors: Massaro, A., Messe, S. R., Acker, M. A., Kasner, S. E., Torres, J., Fanning, M., Giovannetti, T., Ratcliffe, S. J., Bilello, M., Szeto, W. Y., Bavaria, J. E., Mohler, E. R., Floyd, T. F., for the Determining Neurologic Outcomes From Valve Operations (DeNO Tags: Valvular Heart Disease, Magnetic Resonance Imaging (MRI), Cardiovascular Surgery, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Atherosclerotic Plaques in the Aortic Arch and Subclinical Cerebrovascular Disease Clinical Sciences
Conclusions—Aortic arch atherosclerosis was associated with WMHV in a stroke-free community-based elderly cohort. This association was stronger in subjects with large plaques and independent of cardiovascular risk factors. Aortic arch assessment by transthoracic echocardiography may help identify subjects at higher risk of subclinical cerebrovascular disease, who may benefit from aggressive stroke risk factors treatment.
Source: Stroke - October 23, 2016 Category: Neurology Authors: Tugcu, A., Jin, Z., Homma, S., Elkind, M. S. V., Rundek, T., Yoshita, M., DeCarli, C., Nakanishi, K., Shames, S., Wright, C. B., Sacco, R. L., Di Tullio, M. R. Tags: Cerebrovascular Disease/Stroke, Atherosclerosis Original Contributions Source Type: research

Evolutional Characterization of Photochemically Induced Stroke in Rats: a Multimodality Imaging and Molecular Biological Study
In conclusion, these characterizations may be highly beneficial to the development of therapeutic strategies for ischemi c stroke.
Source: Translational Stroke Research - November 30, 2016 Category: Neurology Source Type: research

Prediction of Blood-Brain Barrier Disruption and Intracerebral Hemorrhagic Infarction Using Arterial Spin-Labeling Magnetic Resonance Imaging Clinical Sciences
Background and Purpose—Arterial spin-labeling magnetic resonance imaging is sensitive for detecting hyperemic lesions (HLs) in patients with acute ischemic stroke. We evaluated whether HLs could predict blood–brain barrier (BBB) disruption and hemorrhagic transformation (HT) in acute ischemic stroke patients.Methods—In a retrospective study, arterial spin-labeling was performed within 6 hours of symptom onset before revascularization treatment in 25 patients with anterior circulation large vessel occlusion on baseline magnetic resonance angiography. All patients underwent angiographic procedures intended for endovasc...
Source: Stroke - December 22, 2016 Category: Neurology Authors: Takeya Niibo, Hajime Ohta, Shirou Miyata, Ichiro Ikushima, Kazuchika Yonenaga, Hideo Takeshima Tags: Imaging, Magnetic Resonance Imaging (MRI), Blood-Brain Barrier, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Relationship Between Changes in the Temporal Dynamics of the Blood-Oxygen-Level-Dependent Signal and Hypoperfusion in Acute Ischemic Stroke Clinical Sciences
Conclusions—BOLD delay is related to macrovascular delay and microvascular hypoperfusion, can identify severely hypoperfused tissue in acute stroke, and is a promising alternative to gadolinium contrast agent–based perfusion assessment in acute stroke.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00715533 and NCT02077582.
Source: Stroke - March 27, 2017 Category: Neurology Authors: Ahmed A. Khalil, Ann-Christin Ostwaldt, Till Nierhaus, Ramanan Ganeshan, Heinrich J. Audebert, Kersten Villringer, Arno Villringer, Jochen B. Fiebach Tags: Functional Magnetic Resonance Imaging (fMRI), Magnetic Resonance Imaging (MRI) Original Contributions Source Type: research

Predicting Domain-Specific Health-Related Quality of Life Using Acute Infarct Volume Clinical Sciences
Background and Purpose—Limited data exist on the relationship between acute infarct volume and health-related quality of life (HRQOL) measures after ischemic stroke. We evaluated whether acute infarct volume predicts domain-specific Neuro-Quality of Life scores at 3 months after stroke.Methods—Between 2012 and 2014, we prospectively enrolled consecutive patients with ischemic stroke and calculated infarct volume. Outcome scores at 3 months included modified Rankin Scale and Neuro-Quality of Life T scores. We evaluated whether volume organized by quartiles predicted modified Rankin Scale and HRQOL scores at 3 months usi...
Source: Stroke - June 26, 2017 Category: Neurology Authors: Chen Lin, Jungwha Lee, Neil Chatterjee, Carlos Corado, Timothy Carroll, Andrew Naidech, Shyam Prabhakaran Tags: Magnetic Resonance Imaging (MRI), Quality and Outcomes, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

Admission Brain Cortical Volume Clinical Sciences
Conclusions—Smaller cortical volumes in fronto-temporo-insular areas measured 24 to 72 hours post stroke are associated with cognitive vulnerability in the subacute stroke phase.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Sharmila Sagnier, Gwenaelle Catheline, Bixente Dilharreguy, Fanny Munsch, Antoine Bigourdan, Mathilde Poli, Sabrina Debruxelles, Stephane Olindo, Pauline Renou, Francois Rouanet, Vincent Dousset, Thomas Tourdias, Igor Sibon Tags: Magnetic Resonance Imaging (MRI), Cognitive Impairment, Ischemic Stroke Original Contributions Source Type: research

Does the Primary Imaging Modality —Computed Tomography or Magnetic Resonance Imaging—Influence Stroke Physicians' Certainty on Whether or Not to Give Thrombolysis to Randomized Acute Stroke Patients?
Door-to-needle time of 20 minutes to stroke patients with intravenous tissue plasminogen activator (iv-tPA) is feasible when computed tomography (CT) is used as first-line of brain imaging. Magnetic resonance imaging (MRI)-based assessment is more time-consuming but superior in detecting acute ischemia. The certainty with which stroke physicians prescribe or refrain from giving iv-tPA treatment to CT- versus MRI-examined patients has not previously been studied. The aim of the present study was to determine the effect of a primary imaging strategy of CT or MRI on clinicians' certainty to prescribe or refrain from giving iv...
Source: Journal of Stroke and Cerebrovascular Diseases - November 30, 2017 Category: Neurology Authors: Christine Krarup Hansen, Anders Christensen, Helen Rodgers, Inger Havsteen, Christina Kruuse, Hanne Christensen Source Type: research