Filtered By:
Condition: Stroke
Education: Academia

This page shows you your search results in order of relevance. This is page number 4.

Order by Relevance | Date

Total 2005 results found since Jan 2013.

Glibenclamide Administration Attenuates Infarct Volume, Hemispheric Swelling, and Functional Impairments following Permanent Focal Cerebral Ischemia in Rats.
Authors: Wali B, Ishrat T, Atif F, Hua F, Stein DG, Sayeed I Abstract Studies from a single laboratory have shown that in rodent models of permanent stroke, administration of the sulfonylurea glibenclamide (Glib) is highly effective in reducing edema, mortality, and lesion volume. The Stroke Therapy Academic Industry Roundtable (STAIR) recommends that new acute treatments for ischemic stroke to be replicated across different laboratories. Accordingly, we examined the effect of low-dose Glib in a permanent suture occlusion model of stroke. Male Sprague-Dawley rats underwent permanent middle cerebral artery occlusion...
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research

Does Emergency department length of stay affect the 90-day functional outcome after acute ischemic stroke? (P3.073)
Conclusion: In our cohort, there was no association between the ED-LOS and 90-day functional outcome. Further study is ongoing to assess whether ED-LOS adversely affects outcome measures not captured by the mRS.Disclosure: Dr. Patel has nothing to disclose. Dr. Minaeian has nothing to disclose. Dr. Tunguturi has nothing to disclose. Dr. Goddeau has nothing to disclose. Dr. Henninger has received personal compensation in an editorial capacity for Stroke.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Patel, A., Minaeian, A., Tunguturi, A., Goddeau, R., Henninger, N. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Outcome Source Type: research

Strategies for Optimizing Acute Ischemic Stroke Care by Reducing Door to Needle Time in a Major Academic Center (P4.280)
Conclusion: Through the identification and analysis of key metrics in the acute stroke pathway by the neurology team, DTN times were significantly improved within a brief period of time. As the benefits of IV tPA are time dependent, it is critical that hospitals work to optimize acute stroke protocols. By implementing the innovative changes of the neurology house staff, institutions nationwide can achieve similar rapid gains in DTN times and provide effective treatment to a greater percentage of patients with acute ischemic stroke.Disclosure: Dr. Abraham has nothing to disclose. Dr. Oksienik has nothing to disclose. Dr. Be...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Abraham, J., Oksienik, C., Bell, R., Skidmore, C., Tzeng, D., Pineda, C. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Ischemic Stroke Care Source Type: research

Routine troponin measurements are unnecessary in acute ischemic stroke evaluations (P4.285)
CONCLUSIONS: Troponin elevation in patients with ischemic stroke is not caused by acute myocardial ischemia unless iatrogenic in the setting of vasopressor administration. Serum troponins should be measured based on clinical context rather than routinely in all acute ischemic stroke patients.Disclosure: Dr. Ali has nothing to disclose. Dr. Young has nothing to disclose. Dr. Rabinstein has received royalty payments from Elsevier and Oxford University Press. Dr. Rabinstein has received research support from DJO Global. Dr. Flemming has nothing to disclose. Dr. Fugate has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Ali, F., Young, J., Rabinstein, A., Flemming, K., Fugate, J. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Ischemic Stroke Care Source Type: research

Target Stroke Implementation: Best Practice Strategies Cut Thrombolysis Time to < 30 minutes in a 1,550 Bed Academic Urban County Hospital (P4.280)
Conclusions:Individualized hospital gap analysis identifies targeted interventions to shorten treatment times. DTN and DTG time can be reduced with implementation of simple, low-cost interventions, with persistent effect and no increase in symptomatic intracranial hemorrhage or stroke mimic treatment.Disclosure: Dr. Marulanda-Londoño has nothing to disclose. Dr. Bhatt has nothing to disclose. Dr. Atchaneeyasakul has nothing to disclose. Dr. Asdaghi has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Akram has nothing to disclose. Dr. Zhang has nothing to disclose. Dr. D’Amour has nothing to disclos...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Marulanda-Londono, E., Bhatt, N., Atchaneeyasakul, K., Asdaghi, N., Malik, A., Akram, N., Zhang, T., DAmour, D., Hesse, K., Sacco, R., Romano, J. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Pilot study of volume contracted state and hospital outcome after stroke
Conclusions Acute stroke patients in a VCS demonstrate worse short-term outcomes compared to euvolemic patients, independent of infarct size. Results suggest an opportunity to explore current hydration practices.
Source: Neurology Clinical Practice - February 12, 2018 Category: Neurology Authors: Bahouth, M. N., Gaddis, A., Hillis, A. E., Gottesman, R. F. Tags: Outcome research, Medical care, All Cerebrovascular disease/Stroke, Critical care Source Type: research

A Stroke Care Model at an Academic, Comprehensive Stroke Center During the 2020 COVID-19 Pandemic
The COVID-19 pandemic has required the adaptation of hyperacute stroke care (including stroke code pathways) and hospital stroke management. There remains a need to provide rapid and comprehensive assessment to acute stroke patients while reducing the risk of COVID-19 exposure, protecting healthcare providers, and preserving personal protective equipment (PPE) supplies. While the COVID infection is typically not a primary cerebrovascular condition, the downstream effects of this pandemic force adjustments to stroke care pathways to maintain optimal stroke patient outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - May 6, 2020 Category: Neurology Authors: Dawn Meyer, Brett C. Meyer, Karen S. Rapp, Royya Modir, Kunal Agrawal, Lovella Hailey, Melissa Mortin, Richard Lane, Tamra Ranasinghe, Brian Sorace, Tara D. von Kleist, Emily Perrinez, Mohammed Nabulsi, Thomas Hemmen Source Type: research

Incidence of post-stroke depression symptoms and potential risk factors in adults with aphasia in a comprehensive stroke center
CONCLUSIONS: These findings align with earlier evidence identifying aphasia as a risk factor for experiencing PSD symptoms and also suggest aphasia severity is proportionate to the risk. This highlights the need for early identification of PSD symptoms in persons with aphasia in order to provide timely interventions.PMID:35543182 | DOI:10.1080/10749357.2022.2070363
Source: Topics in Stroke Rehabilitation - May 11, 2022 Category: Neurology Authors: Christina Zanella Jacqueline Laures-Gore Vonetta M Dotson Samir R Belagaje Source Type: research

Impact of Telemedicine Implementation in Thrombolytic Use for Acute Ischemic Stroke: The University of Pittsburgh Medical Center Telestroke Network Experience
Background: Intravenous thrombolysis is the only therapy for acute ischemic stroke that is approved by the US Food and Drug Association. The use of telemedicine in stroke makes it possible to bring the expertise of academic stroke centers to underserved areas, potentially increasing the quality of stroke care.Methods: All consecutive admissions for stroke were reviewed for 1 year before telemedicine implementation and for variable periods thereafter. A retrospective review identified 2588 admissions for acute stroke between March 2005 and December 2008 at 12 hospitals participating in a telestroke network, including 919 pa...
Source: Journal of Stroke and Cerebrovascular Diseases - March 13, 2013 Category: Neurology Authors: Edilberto Amorim, Min-Mei Shih, Steven A. Koehler, Lori L. Massaro, Syed F. Zaidi, Mouhammad A. Jumaa, Vivek K. Reddy, Maxim D. Hammer, Tudor G. Jovin, Lawrence R. Wechsler Tags: Original Articles Source Type: research

Venous Thromboembolism in the Get With The Guidelines-Stroke Acute Ischemic Stroke Population: Incidence and Patterns of Prophylaxis
Conclusions: Despite a high overall rate of VTE prophylaxis, VTE was found to occur in approximately 3% of GWTG-S patients. Reported rates of VTE prophylaxis differed among hospitals by region and hospital type, and among patients by age, race, and medical comorbidities.
Source: Journal of Stroke and Cerebrovascular Diseases - December 17, 2012 Category: Neurology Authors: G. Logan Douds, Anne S. Hellkamp, DaiWai M. Olson, Gregg C. Fonarow, Eric E. Smith, Lee H. Schwamm, Kevin M. Cockroft Tags: Original Articles Source Type: research

Socioeconomic Status Inconsistency and Risk of Stroke Among Japanese Middle-Aged Women Clinical Sciences
Conclusions— High academic qualifications without an appropriate job could be a risk factor for stroke among Japanese women. Our result suggests that status inconsistency could be a potential explanation for the increased stroke risk among highly educated women.
Source: Stroke - August 25, 2014 Category: Neurology Authors: Honjo, K., Iso, H., Inoue, M., Sawada, N., Tsugane, S., for the JPHC Study Group Tags: Epidemiology Clinical Sciences Source Type: research

To Treat or Not to Treat?: Pilot Survey for Minor and Rapidly Improving Stroke Brief Reports
Conclusions— This pilot survey provides the first quantitative evidence that National Institutes of Health Stroke Scale score is not the only determinant of treatment decision. A National Institutes of Health Stroke Scale score of 2 is the potential equipoise point, with the least consensus on treatment decision. These preliminary findings require validation in larger population surveys.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Balucani, C., Bianchi, R., Feldmann, E., Weedon, J., Kolychev, D., Levine, S. R. Tags: Thrombolysis Brief Reports Source Type: research

Do efforts to decrease door-to-needle time risk increasing stroke mimic treatment rates?
An unintended consequence of rapid thrombolysis may be more frequent treatment of stroke mimics, nonvascular conditions that simulate stroke. We explored the relationship between door-to-needle (DTN) times and thrombolysis of stroke mimics at a single academic center by analyzing consecutive quartiles of patients who were treated with IV tissue plasminogen activator for suspected stroke from January 1, 2010 to February 28, 2014. An increase in the proportion of stroke mimic patients (6.7% in each of the 1st and 2nd, 12.9% in the 3rd, and 30% in the last consecutive case quartile; p = 0.03) and a decrease in median DTN time...
Source: Nature Clinical Practice - June 8, 2015 Category: Neurology Authors: Liberman, A. L., Liotta, E. M., Caprio, F. Z., Ruff, I., Maas, M. B., Bernstein, R. A., Khare, R., Bergman, D., Prabhakaran, S. Tags: Harm/ risk (analysis), All Cerebrovascular disease/Stroke, Infarction Eye on Practice Source Type: research