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Condition: Schizophrenia
Drug: Nicotine
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Total 137 results found since Jan 2013.
Fight Aging! Newsletter, August 14th 2023
This study demonstrates just how vital the thymus is to maintaining adult health."
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Does Amyloid-β Aggregation Cause Broad Disruption of Proteostasis?
https://www.fightaging.org/archives/2023/08/does-amyloid-%ce%b2-aggregation-cause-broad-disruption-of-proteostasis/
Researchers here speculate on the ability of insoluble amyloid-β aggregates to be broadly disruptive of the solubility of many other proteins, and thus disruptive to cell and tissue function. Is this important in aging? The evidence here shows the existence of the mechanism in a lower species, but that doesn't n...
Source: Fight Aging! - August 13, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Acute effects of exercise among individuals with schizophrenia who smoke cigarettes
Addict Behav. 2023 May 5;144:107749. doi: 10.1016/j.addbeh.2023.107749. Online ahead of print.ABSTRACTPeople with schizophrenia (SCZ) have a shorter life expectancy than those without psychiatric conditions. Of note, people with SCZ have high rates of cigarette smoking, physical inactivity, and obesity. These factors all coalesce to contribute to compromised health in this population, with smoking as a primary contributor. Therefore, it is paramount to develop effective smoking cessation strategies for this population. The purpose of this study was to investigate whether walking at a brisk pace, relative to engaging in pas...
Source: Addictive Behaviors - May 12, 2023 Category: Addiction Authors: Cara M Murphy Michael C Onu Christine Goodwin David M Williams Jennifer W Tidey Source Type: research
Smoking status ameliorates cholinergic impairments in cortical inhibition in patients with schizophrenia
CONCLUSION: Our results suggest an increased inhibition within cholinergic circuits due to chronic nicotine consumption in schizophrenia. This increase may compensate impaired cholinergic neurotransmission and could explain the high rate of smokers in schizophrenia.PMID:37121425 | DOI:10.1016/j.brainres.2023.148380
Source: Brain Research - April 30, 2023 Category: Neurology Authors: Benjamin Pross Susanne M ünz Michael A Nitsche Frank Padberg Wolfgang Strube Irina Papazova Peter Falkai Alkomiet Hasan Source Type: research
Lorcaserin: worthy of further insights? Results from recent research
CNS Neurol Disord Drug Targets. 2023 Mar 30. doi: 10.2174/1871527322666230330124137. Online ahead of print.ABSTRACTLorcaserin is a 3-benzazepine that binds 5-HT2C serotonin receptors in the hypothalamus, where it mediates lack of hunger and/or satiety, and in the ventral tegmental area, the site of origin of the mesolimbic and mesocortical dopaminergic projections, which mediate pleasure and reward. The drug has been first developed for the treatment of obesity, where it has shown efficacy, and subsequently trialed to counter substance use (mostly cocaine, cannabis, opioids, and nicotine) and craving, but showed inconsiste...
Source: CNS and Neurological Disorders Drug Targets - April 3, 2023 Category: Drugs & Pharmacology Authors: Marianna Mazza Georgios Demetrios Kotzalidis Giuseppe Marano Domenico De Berardis Giovanni Martinotti Enrico Romagnoli Giuseppe Biondi-Zoccai Antonio Abbate Gabriele Sani Source Type: research
Does tobacco dependence worsen cannabis withdrawal in people with and without schizophrenia-spectrum disorders?
CONCLUSION AND SCIENTIFIC SIGNIFICANCE: Among individuals with CUD and high tobacco dependence, cannabis withdrawal severity was elevated twofold, irrespective of diagnosis, relative to individuals with CUD and no/low tobacco dependence. Findings from this study emphasize the importance of addressing tobacco co-use when treating CUD.PMID:36815595 | DOI:10.1111/ajad.13394
Source: American Journal on Addictions - February 23, 2023 Category: Addiction Authors: Zac J S Yeap Justine Marsault Tony P George Romina Mizrahi Rachel A Rabin Source Type: research
