• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Case Report: Acute Cerebellar Thrombosis in an Adult Patient with IgM Nephropathy.
We describe a patient who presented with nonspecific symptoms of epigastric pain, nausea, and early satiety. Abdominal imaging and endoscopies were unremarkable. She was found to have significant proteinuria (6.4 g/24 hours), hyperlipidemia, and edema consistent with a diagnosis of nephrotic syndrome. Kidney biopsy was performed and confirmed an IgM nephropathy. Less than 2 weeks after her diagnosis of IgM nephropathy, she presented with an acute cerebellar stroke. Thrombophilia is a well-known complication of nephrotic syndrome, but a review of the literature failed to show an association between IgM nephropathy and acute...
Source: Methodist DeBakey Cardiovascular Journal - September 30, 2015 Category: Cardiology Authors: Adike A, Cherry M, Awar M Tags: Methodist Debakey Cardiovasc J Source Type: research

Dexmedetomidine and general anesthesia: a narrative literature review of its major indications for use in adults undergoing non-cardiac surgery.
CONCLUSIONS: The properties of dexmedetomidine lead to its use for elective indications such as awake fiberoptic intubation and neurosurgical anesthesia. New topics are under debate. These subjects must be studied thoroughly because of their implication in the patients' surgical course. These advantages must be weighed against the major drawback of dexmedetomidine administration which is the potential for hemodynamic abnormalities. PMID: 28643999 [PubMed - as supplied by publisher]
Source: Minerva Anestesiologica - June 25, 2017 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Esophageal Injury and Atrioesophageal Fistula Caused by Ablation for Atrial Fibrillation.
Abstract Esophageal perforation is a dreaded complication of atrial fibrillation ablation that occurs in 0.1% to 0.25% of atrial fibrillation ablation procedures. Delayed diagnosis is associated with the development of atrial-esophageal fistula (AEF) and increased mortality. The relationship between the esophagus and the left atrial posterior wall is variable, and the esophagus is most susceptible to injury where it is closest to areas of endocardial ablation. Esophageal ulcer seems to precede AEF development, and postablation endoscopy documenting esophageal ulcer may identify patients at higher risk for AEF. AEF...
Source: Circulation - September 26, 2017 Category: Cardiology Authors: Kapur S, Barbhaiya C, Deneke T, Michaud GF Tags: Circulation Source Type: research

Not as Simple as Canker Sores
BY ​NANA P. MATSUMOTO, & DEREK MEEKS, DO​​A 16-year-old boy presented to a rural ED with a swollen jaw, painful blisters in the mouth, and earache for the past day. One week before, he had a fever with chills, sore throat, and dry coughs. He was not taking any medications, and his immunizations were up-to-date. He had a mild learning disorder but no significant past medical or surgical history.​An apthous ulcer, the most common and one of the earliest signs of Behçet's disease.The patient's vital signs were within normal limits, and his physical examination revealed anterior cervical lymphadenopathy, sinus con...
Source: The Case Files - October 11, 2017 Category: Emergency Medicine Tags: Blog Posts Source Type: research

Lymphatic imaging and intervention in a pediatric population: Anesthetic considerations.
Abstract The recent adoption of an improved lymphatic access technique coupled with Dynamic Contrast-enhanced Magnetic Resonance Lymphangiography has introduced the ability to diagnose and treat severe lymphatic disorders unresponsive to other therapies. All pediatric patients presenting for lymphatic procedures require general anesthesia presenting challenges in managing highly morbid and comorbid conditions both from logistical as well as medical aspects. General anesthesia is used because of the procedural requirement for immobility to accurately place needles and catheters, treat pain secondary to contrast and...
Source: Paediatric Anaesthesia - April 23, 2018 Category: Anesthesiology Authors: Jobes DR, Brown LA, Dori Y, Itkin M, Nicolson SC Tags: Paediatr Anaesth Source Type: research

Gastroparesis: Current Opinions and New Endoscopic Therapies
Gastroparesis is a disease with a complex pathophysiology that is not yet fully understood. Antroduodenal hypomotility, impaired fundic accommodation, and pylorospasm are believed to play major roles in delaying gastric emptying. Patients with  gastroparesis suffer from frequent nausea, vomiting, earlier satiety, regurgitation, and so forth. Diabetes is the most common cause. Other causes include gastrointestinal surgery, some disorders of the nervous system, such as Parkinson disease and stroke, and some medicines, such as tricyclic ant idepressants, calcium channel blockers, and opiate pain relievers and others.
Source: Gastrointestinal Endoscopy Clinics of North America - November 3, 2018 Category: Gastroenterology Authors: Huimin Chen, Qiang Cai Tags: Preface Source Type: research

Pressure-Volume Relationships in the Spinal Canal and Potential Neurological Complications After Epidural Fluid Injections
Front Pain Res (Lausanne). 2022 Jul 7;3:884277. doi: 10.3389/fpain.2022.884277. eCollection 2022.ABSTRACTHigh-volume fluid injections into the spinal canal may lead to severe neurological complications. But when anatomical or pathological conditions in the spinal canal are unfavorable, even small volume epidural injections can cause dangerously high epidural, subarachnoid, and intracranial pressures or pressure gradients. Data obtained from the scientific literature and direct clinical observation are used to derive a first-order approximation of epidural, subarachnoid, and intracranial pressure responses to epidural fluid...
Source: Cell Research - July 25, 2022 Category: Cytology Authors: Hemmo Bosscher Source Type: research