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Treatment of status migrainosus by general anesthesia: a case report
Conclusion Status migrainosus is a rare disabling complication and anesthetics have been the subject of research in its treatment; the option for general anesthesia with agents that stimulate GABA receptors, propofol and isoflurane, in association with fentanyl, proved effective and should encourage new research.
Source: Brazilian Journal of Anesthesiology - August 29, 2015 Category: Anesthesiology Source Type: research

A preliminary investigation into psychophysiological effects of threatening a perceptually embodied rubber hand in healthy human participants
Conclusion and implications Our preliminary findings suggest that the increase in arousal in response to stimuli entering the peripersonal space may not be selective for threat. There was tentative evidence that more intense sensations were experienced when a perceptually embodied rubber hand was approached by a threatening stimulus. Our findings provide initial insights and should serve as a catalyst for further research.
Source: Scandinavian Journal of Pain - November 8, 2015 Category: Anesthesiology Source Type: research

Mini-fluid challenge can predict arterial pressure response to volume expansion in spontaneously breathing patients under spinal anaesthesia
Conclusion A ΔSV100 over 5% accurately predicted arterial pressure response to volume expansion during surgery.
Source: Anaesthesia, Critical Care and Pain Medicine - December 1, 2015 Category: Anesthesiology Source Type: research

Cardiovascular effects of low-dose spinal anaesthesia as a function of age: An observational study using echocardiography
Conclusions Hypotension is more frequent among elderly patients, even after low-dose SA. Known age-related changes in cardiovascular performance, such as impaired myocardial relaxation and decreased systolic function could be responsible for the decrease in cardiac output (CO) and SVR seen in these patients.
Source: Anaesthesia, Critical Care and Pain Medicine - December 1, 2015 Category: Anesthesiology Source Type: research

In-hospital organization of primary care of patients presenting a life-threatening emergency: A French national survey in 32 university hospitals
Conclusion This survey is the first to assess the in-hospital organization of primary care for instable and life-threatening patients in France. Our results confirmed the extreme heterogeneity of structural and human organizations for primary in-hospital care of patients presenting at least one organ failure. Thus, a consensus is probably needed to homogenize and improve our practices.
Source: Anaesthesia, Critical Care and Pain Medicine - December 1, 2015 Category: Anesthesiology Source Type: research

Adult neurogenesis and brain remodelling after brain injury: From bench to bedside?
Conclusion The concept of brain remodelling upset fundamental ideas concerning the neurologic system and opened new fields of research. Therapies currently under evaluation hold promising results and could have a real prognostic impact in future years, but the translation of these therapies from the laboratory to the clinic is still far from completion.
Source: Anaesthesia, Critical Care and Pain Medicine - December 1, 2015 Category: Anesthesiology Source Type: research

Can public health registry data improve Emergency Medical Dispatch?
ConclusionIncreasing age, male sex, and hospitalization history was associated with increased risk of death on day 1 for FHQ 112 callers. Additional efforts are warranted to clarify the role for risk prediction tools in emergency medical dispatch.
Source: Acta Anaesthesiologica Scandinavica - December 9, 2015 Category: Anesthesiology Authors: M S. Andersen, E. F. Christensen, S. B. Jepsen, J. Nørtved, J. B. Hansen, S. P. Johnsen Tags: Original Article Source Type: research

Thalamic Pain Misdiagnosed as Cervical Disc Herniation.
We report a case of CPSP due to a left acute thalamic infarction with central disc protrusion at C5-6. A 45-year-old-male patient experiencing a tingling sensation in his right arm was referred to our pain clinic under the diagnosis of cervical disc herniation. This patient also complained of right cramp-like abdominal pain. After further evaluations, he was diagnosed with an acute thalamic infarction. Therefore detailed history taking should be performed and examiners should always be aware of other symptoms that could suggest a more dangerous disease. PMID: 27103967 [PubMed]
Source: Korean Journal of Pain - April 24, 2016 Category: Anesthesiology Tags: Korean J Pain Source Type: research

Iatrogenic dissection of the descending aorta: Conservative or endovascular treatment?
In this report, we refer the bibliographic data and we discuss the treatment options in these cases. PMID: 27397470 [PubMed - in process]
Source: Annals of Cardiac Anaesthesia - June 30, 2016 Category: Anesthesiology Authors: Baikoussis NG, Argiriou M, Kratimenos T, Karameri V, Dedeilias P Tags: Ann Card Anaesth Source Type: research

Old Drug, New Route: A Systematic Review of Intravenous Acetaminophen After Adult Cardiac Surgery
THE MANAGEMENT OF postoperative pain after cardiac surgery remains clinically challenging. Well-controlled pain is critical to maintaining the physical and psychologic well-being of each patient and can help facilitate timely extubation, comfortable breathing, and early postoperative ambulation. On the other hand, left poorly managed, postoperative pain can lead to rising catecholamine levels, ultimately triggering myocardial ischemia, stroke, or bleeding complications.1-3 Insufficient pain control also can limit patient mobility, increasing the risk of deep vein thrombosis and pneumonia, in addition to the harmful psychol...
Source: Journal of Cardiothoracic and Vascular Anesthesia - August 2, 2016 Category: Anesthesiology Authors: Daniel J. Douzjian, Alexander Kulik Tags: Review ArticleGiovanni Landoni, MDSection Editors? > Source Type: research

Complex neuropathic pain states
Publication date: Available online 23 September 2016 Source:Anaesthesia & Intensive Care Medicine Author(s): Rhian P. Lewis, Indre Kriukelyte In this article we discuss complex neuropathic pain states: diabetic peripheral neuropathic pain (DPNP), phantom limb pain (PLP), central post-stroke pain (CPSP), and complex regional pain syndrome (CRPS). Pain in these conditions can often be severe, significantly affect quality of life and be resistant to current treatment options. Multidisciplinary assessment and treatment is essential.
Source: Anaesthesia and intensive care medicine - September 23, 2016 Category: Anesthesiology Source Type: research

The Genetics of Pain
This article aims to review some human pain conditions, both common and rare, and their possible association with ion channels, receptors and the genes involved. Current and ongoing research evidence of the involvement of multiple cellular and molecular pathways in pain, advances in gene therapy and new medications are mentioned, as well as their limitations due to the complexity of pain.
Source: Current Anesthesiology Reports - November 16, 2016 Category: Anesthesiology Source Type: research

Mechanical pinprick pain in patients with unilateral spatial neglect: The influence of space representation on the perception of nociceptive stimuli
ConclusionThese findings uphold the notion that the perception of nociceptive stimuli is modulated by the relative position of the hands in space, but raise questions about the conditions under which these effects may arise. SignificanceWe show that deficits in space representation can influence the processing of mechanical pinprick stimuli. Our results raise several questions on the mechanisms underlying these effects, which are relevant for the clinical practice.
Source: European Journal of Pain - December 14, 2016 Category: Anesthesiology Authors: V. Vizzari, S. Barba, P. Gindri, S. Duca, D. Giobbe, P. Cerrato, G. Geminiani, D.M. Torta Tags: Original Article Source Type: research

Delirium after cardiac surgery: A pilot study from a single tertiary referral center.
CONCLUSIONS: Patients who developed delirium had systemic disease in the form of hypertension and cerebrovascular disease. Delirium was seen in patients who had higher postoperative pain scores, longer ICU stay, and NIV use. This study can be used to develop a predictive tool for diagnosing postcardiac surgical delirium. PMID: 28074801 [PubMed - in process]
Source: Annals of Cardiac Anaesthesia - December 31, 2016 Category: Anesthesiology Authors: Kumar AK, Jayant A, Arya VK, Magoon R, Sharma R Tags: Ann Card Anaesth Source Type: research

In Vogue: Ketamine for Neuroprotection in Acute Neurologic Injury.
Abstract Neurologic deterioration following acute injury to the central nervous system may be amenable to pharmacologic intervention, although, to date, no such therapy exists. Ketamine is an anesthetic and analgesic emerging as a novel therapy for a number of clinical entities in recent years, including refractory pain, depression, and drug-induced hyperalgesia due to newly discovered mechanisms of action and new application of its known pharmacodynamics. In this focused review, the evidence for ketamine as a neuroprotective agent in stroke, neurotrauma, subarachnoid hemorrhage, and status epilepticus is highligh...
Source: Anesthesia and Analgesia - January 9, 2017 Category: Anesthesiology Authors: Bell JD Tags: Anesth Analg Source Type: research

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