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Specialty: Cardiology
Condition: Hypertension

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Total 3701 results found since Jan 2013.

Sex Differences in Outcomes of Ticagrelor Therapy With or Without Aspirin After Percutaneous Coronary Intervention in Patients With Acute Coronary Syndrome: A Post Hoc Secondary Analysis of the TICO Randomized Clinical Trial
CONCLUSIONS: After percutaneous coronary intervention for acute coronary syndrome, women demonstrated worse clinical outcomes than men. Ticagrelor monotherapy after 3-month dual-antiplatelet therapy was associated with significantly lower risk of net adverse clinical events in women without sex interaction.PMID:37021576 | DOI:10.1161/ATVBAHA.122.318725
Source: Arteriosclerosis, Thrombosis and Vascular Biology - April 6, 2023 Category: Cardiology Authors: Bom Lee Seung-Jun Lee Byeong-Keuk Kim Yong-Joon Lee Sung-Jin Hong Chul-Min Ahn Jung-Sun Kim Young-Guk Ko Donghoon Choi Meyong-Ki Hong Yangsoo Jang Source Type: research

The incomplete circle of Willis is associated with vulnerable intracranial plaque features and acute ischemic stroke
CONCLUSIONS: This study demonstrated that incomplete A-CoW was associated with enhancement grade of the culprit plaque, and incomplete symptomatic side P-CoW was associated with the presence of HT1S of culprit plaque. Furthermore, an irregularity of plaque surface and incomplete symptomatic side P-CoW were associated with AIS.PMID:37020230 | DOI:10.1186/s12968-023-00931-2
Source: Atherosclerosis - April 5, 2023 Category: Cardiology Authors: Huiying Wang Lianfang Shen Chenxi Zhao Song Liu Gemuer Wu Huapeng Wang Beini Wang Jinxia Zhu Jixiang Du Zhongying Gong Chao Chai Shuang Xia Source Type: research

Cardiac transplant and exercise cardiac rehabilitation
AbstractCardiac transplantation is the final therapeutic option for patients with end-stage heart failure. Most patients experience a favorable functional ability post-transplant. However, episodes of acute rejection, and multiple comorbidities such as hypertension, diabetes mellitus, chronic kidney disease and cardiac allograft vasculopathy are common. The number of transplants has increased steadily over the past two decades with 3,817 operations performed in the United States in 2021. Patients have abnormal exercise physiologic responses related to surgical cardiac denervation, diastolic dysfunction, and the legacy of r...
Source: Heart Failure Reviews - April 4, 2023 Category: Cardiology Source Type: research

Comparison of Prasugrel and Clopidogrel in Thrombotic Stroke Patients with Risk Factors for Ischemic Stroke Recurrence: An Integrated Analysis of PRASTRO-I, PRASTRO-II, and PRASTRO-III
CONCLUSIONS: This integrated analysis supports the findings of PRASTRO-III. Prasugrel is a promising treatment that results in a numerical reduction in the composite incidence of ischemic stroke, MI, and death from other vascular causes in patients with ischemic stroke who are at a high risk of stroke recurrence. No major safety issues were observed for prasugrel.PMID:37011599 | DOI:10.1159/000529149
Source: Atherosclerosis - April 3, 2023 Category: Cardiology Authors: Takanari Kitazono Masahiro Kamouchi Yuji Matsumaru Toshiaki Shirai Atsushi Takita Takeshi Kuroda Kazumi Kimura Source Type: research

Periodontitis is associated with subclinical cerebral and carotid atherosclerosis in hypertensive patients: A cross-sectional study
CONCLUSIONS: Periodontitis is associated with subclinical atherosclerosis in both intracranial and carotid arteries in elderly subjects with hypertension.CLINICAL RELEVANCE: The association of periodontitis with intracranial atherosclerosis implies that periodontitis patients might have greater chances to develop ischemic stroke in the future.PMID:37004529 | DOI:10.1007/s00784-023-04958-8
Source: Atherosclerosis - April 2, 2023 Category: Cardiology Authors: Mar ía Vázquez-Reza Iria L ópez-Dequidt Alberto Ouro Ram ón Iglesias-Rey Francisco Campos Juan Blanco Manuel Rodr íguez-Yáñez Jos é Castillo Tom ás Sobrino Yago Leira Source Type: research

Prediction of Coronary Artery Disease Severity by Using CHA2DS2-VASC-HSF Score in Patients with ST-Elevation Myocardial Infarction
In this study mean age of study population was 51.8±9.8, male patients were predominant (79.0%). Among the studied patients, highest percentage had history of smoking followed by hypertension, diabetes mellitus and family history of CAD in Group I patients. It was found that DM and family history of CAD and history of stroke/TIA were significantly higher in Group I than Group II. An increasing trend of SYNTAX score was observed according to the CHA₂DS₂-VASc-HSF score. SYNTAX score was significantly higher in CHA2DS2-VASc-HSF score ≥4 than CHA₂DS₂-VASc-HSF score <4 (26.3±6.3 vs. 12.1±7.7, p<0.001). Patien...
Source: Atherosclerosis - April 1, 2023 Category: Cardiology Authors: M A Rahim M J Uddin J Jahan T A Chowdhury A Momen M M Islam M A Rahman P Bala A Mamun F Chowdhury A R Majumder Source Type: research

Clinical characteristics, etiological profile, treatment and long term outcomes in patients with non ischemic systolic heart failure; Himachal Pradesh heart failure registry (HP-HF registry)
CONCLUSIONS: Patients of NISHF were middle-aged population with severely depressed LV systolic function with significant incident morbidity and mortality. Early detection of risk factors and their risk management and enhancing the use of guideline directed treatment may improve the outcomes.PMID:37003535 | DOI:10.1016/j.ihj.2023.03.007
Source: Indian Heart J - April 1, 2023 Category: Cardiology Authors: Prakash Chand Negi Ashu Gupta Meena Rana Sanjeev Asotra Neeraj Ganju Rajeev Marwah Rajesh Sharma Arvind Kandoria Source Type: research

Prediction of Coronary Artery Disease Severity by Using CHA2DS2-VASC-HSF Score in Patients with ST-Elevation Myocardial Infarction
In this study mean age of study population was 51.8±9.8, male patients were predominant (79.0%). Among the studied patients, highest percentage had history of smoking followed by hypertension, diabetes mellitus and family history of CAD in Group I patients. It was found that DM and family history of CAD and history of stroke/TIA were significantly higher in Group I than Group II. An increasing trend of SYNTAX score was observed according to the CHA₂DS₂-VASc-HSF score. SYNTAX score was significantly higher in CHA2DS2-VASc-HSF score ≥4 than CHA₂DS₂-VASc-HSF score <4 (26.3±6.3 vs. 12.1±7.7, p<0.001). Patien...
Source: Atherosclerosis - April 1, 2023 Category: Cardiology Authors: M A Rahim M J Uddin J Jahan T A Chowdhury A Momen M M Islam M A Rahman P Bala A Mamun F Chowdhury A R Majumder Source Type: research

Association of vascular and degenerative brain pathologies and past medical history from the National Alzheimer's Coordinating Center Database
We examined the following PMH: transient ischemic attack (TIA), stroke, traumatic brain injury, seizures, hypertension, cardiovascular events, hypercholesterolemia, B12 deficiency, diabetes mellitus, and thyroid disease. We dichotomized the following neuropathologies: atherosclerosis, arteriolosclerosis, cerebral amyloid angiopathy (CAA), Alzheimer disease neuropathology (ADNP), Lewy bodies (LB), hippocampal sclerosis, frontotemporal lobar degeneration (FTLD), and TAR DNA-binding protein-43 (TDP-43). Separate logistic regression models assessed the relationship between the outcome of individual neuropathologies and all PMH...
Source: Atherosclerosis - March 22, 2023 Category: Cardiology Authors: Kiana A Scambray Hannah L Nguyen S Ahmad Sajjadi Source Type: research

The role of class IIa histone deacetylases in regulating endothelial function
Front Physiol. 2023 Mar 1;14:1091794. doi: 10.3389/fphys.2023.1091794. eCollection 2023.ABSTRACTVascular endothelial cells (ECs) are monolayer cells located in the inner layer of the blood vessel. Endothelial function is crucial in maintaining local and systemic homeostasis and is precisely regulated by sophisticated signaling pathways and epigenetic regulation. Endothelial dysfunctions are the main factors for the pathophysiological process of cardiovascular and cerebrovascular diseases like atherosclerosis, hypertension, and stroke. In these pathologic processes, histone deacetylases (HDACs) involve in epigenetic regulat...
Source: Atherosclerosis - March 20, 2023 Category: Cardiology Authors: Zexu Shen Yun Bei Haoran Lin Taofeng Wei Yunjian Dai Yangmin Hu Chao Zhang Haibin Dai Source Type: research

The Association between Dietary Carotenoid Intake and Risk of Depression among Patients with Cardiometabolic Disease
This study aimed to assess the association of dietary carotenoid intake with risk of depression among patients with cardiometabolic disease.Data were obtained from the 2005 to 2014 National Health and Nutrition Examination Survey. Participants aged ≥ 20 years with any chronic cardiometabolic diseases, including diabetes, hypertension, coronary heart disease, heart failure, and stroke, were included in this cross-sectional study.We enrolled a total of 8655 cardiometabolic disease patients in the analysis. Compared to those in the lowest tertile, patients with cardiometabolic disease in the third tertiles of dietary α-car...
Source: International Heart Journal - March 17, 2023 Category: Cardiology Authors: Jie Liang Yuhao Wang Min Chen Source Type: research

Effect of atherosclerosis on 5-year risk of major vascular events in patients with transient ischaemic attack or minor ischaemic stroke: an international prospective cohort study
Lancet Neurol. 2023 Apr;22(4):320-329. doi: 10.1016/S1474-4422(23)00067-4.ABSTRACTBACKGROUND: The prevalence of atherosclerosis and the long-term risk of major vascular events in people who have had a transient ischaemic attack or minor ischaemic stroke, regardless of the causal relationship between the index event and atherosclerosis, are not well known. In this analysis, we applied the ASCOD (atherosclerosis, small vessel disease, cardiac pathology, other causes, and dissection) grading system to estimate the 5-year risk of major vascular events according to whether there was a causal relationship between atherosclerosis...
Source: Atherosclerosis - March 17, 2023 Category: Cardiology Authors: Philippa C Lavall ée Hugo Charles Gregory W Albers Louis R Caplan Geoffrey A Donnan Jos é M Ferro Michael G Hennerici Julien Labreuche Carlos Molina Peter M Rothwell Philippe Gabriel Steg Pierre-Jean Touboul Shinichiro Uchiyama Éric Vicaut Lawrence K S Source Type: research