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Specialty: Cardiology
Condition: Hypertension

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Total 3701 results found since Jan 2013.

Pollution from fine particulate matter and atherosclerosis: A narrative review
Environ Int. 2023 Apr 10;175:107923. doi: 10.1016/j.envint.2023.107923. Online ahead of print.ABSTRACTAccording to the WHO, the entire global population is exposed to air pollution levels higher than recommended for health preservation. Air pollution is a complex mixture of nano- to micro-sized particles and gaseous components that poses a major global threat to public health. Among the most important air pollutants, causal associations have been established between particulate matter (PM), mainly < 2.5 μm, and cardiovascular diseases (CVD), i.e., hypertension, coronary artery disease, ischemic stroke, congestive heart...
Source: Atherosclerosis - April 29, 2023 Category: Cardiology Authors: Chiara Macchi Cesare R Sirtori Alberto Corsini Pier Mannuccio Mannucci Massimiliano Ruscica Source Type: research

Prevalence and impact of cerebrovascular risk factors in patients with giant cell arteritis: An observational study from the Spanish national registry
CONCLUSION: Hypertension, along with male sex, was the strongest risk factor for cerebrovascular events in GCA patients. In these high-risk patients, antiplatelet therapy should be re-considered and evaluated in prospective studies.PMID:37105843 | DOI:10.1016/j.medcli.2023.04.004
Source: Atherosclerosis - April 27, 2023 Category: Cardiology Authors: Enrique S ánchez-Chica Mar ía Martínez-Urbistondo Ángela Gutiérrez Rojas Raquel Castej ón Juan A Vargas-N úñez V íctor Moreno-Torres Source Type: research

Impact of multimorbidity on mortality in heart failure with reduced ejection fraction: which comorbidities matter most? An analysis of PARADIGM ‐HF and ATMOSPHERE
ConclusionsIn HF, the impact of multimorbidity differed at the individual patient and population level, depending on the prevalence of and the risk related to each comorbidity, and the interaction between individual comorbidities. Patients with coexistent PAD and stroke were at greatest individual risk whereas, from a population perspective, coexistent CKD and hypertension mattered most.
Source: European Journal of Heart Failure - April 25, 2023 Category: Cardiology Authors: Pooja Dewan, Jo ão Pedro Ferreira, Jawad H. Butt, Mark C. Petrie, William T. Abraham, Akshay S. Desai, Kenneth Dickstein, Lars Køber, Milton Packer, Jean L. Rouleau, Simon Stewart, Karl Swedberg, Michael R. Zile, Scott D. Solomon, Pardeep Tags: Research Article Source Type: research

How much does hypertension in pregnancy affect the risk of future cardiovascular events?
Eur Heart J Suppl. 2023 Apr 21;25(Suppl B):B111-B113. doi: 10.1093/eurheartjsupp/suad085. eCollection 2023 Apr.ABSTRACTHypertensive disorders in pregnancy (HDP) include essential (or secondary) hypertension occurring before 20 weeks of gestation or in women already on antihypertensive therapy prior to pregnancy, gestational hypertension, developing after 20 weeks of gestation without significant proteinuria, and pre-eclampsia or AH onset after 20 weeks of pregnancy in the presence of proteinuria. The development of HDP is associated with a higher incidence of long-term cardiovascular (CV) adverse events, such as myocardial...
Source: Atherosclerosis - April 24, 2023 Category: Cardiology Authors: Gian Francesco Mureddu Source Type: research

Soluble Guanylate Cyclase Activators and Stimulators in Patients with Heart Failure
AbstractPurpose of ReviewThis review sought to summarize the current emerging soluble guanylate cyclase activators and stimulators in patients with heart failure, both heart failure with reduced and preserved ejection fraction, to provide a reference for soluble guanylate cyclase activators and stimulators discovery.Recent FindingsHeart failure is a common disease with considerable morbidity, hospitalization, and mortality Soluble guanylate cyclase is a key enzyme in the nitric oxide signaling pathway and has attracted rapidly growing interest as a therapeutic target in heart failure. Currently, several soluble guanylate c...
Source: Current Cardiology Reports - April 20, 2023 Category: Cardiology Source Type: research

Triglyceride-glucose index, symptomatic intracranial artery stenosis and recurrence risk in minor stroke patients with hypertension
CONCLUSION: TyG is a significant risk factor for sICAS in hypertensive patients, and there is a synergistic effect of sICAS and higher TyG on ischemic stroke recurrence.TRIAL REGISTRATION NUMBER: The study was registered on 16 August 2019 at https://www.chictr.org.cn/showprojen.aspx?proj=41160 (No. ChiCTR1900025214).PMID:37076850 | DOI:10.1186/s12933-023-01823-6
Source: Atherosclerosis - April 19, 2023 Category: Cardiology Authors: Yongle Wang Tingting Liu Yanan Li Kaili Zhang Haimei Fan Jing Ren Juan Li Yali Li Xinyi Li Xuemei Wu Junhui Wang Lixi Xue Xiaolei Gao Yuping Yan Gaimei Li Qingping Liu Wenhua Niu Wenxian Du Yuting Liu Xiaoyuan Niu Source Type: research

Artificial Intelligence for the Detection and Treatment of Atrial Fibrillation
AF, the most common clinically relevant cardiac arrhythmia, is expected to affect>5 million Americans by 2050.1 The diagnosis is frequently associated with other cardiovascular comorbidities, including hypertension, obesity and sleep apnoea, and AF is an important risk factor for stroke, heart failure and overall mortality.2 –4 Although treatment is available, many people remain untreated becau...
Source: Radcliffe Cardiology - April 19, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research

Triglyceride-glucose index, symptomatic intracranial artery stenosis and recurrence risk in minor stroke patients with hypertension
The triglyceride-glucose (TyG) index, a simple measure of insulin resistance, is associated with intracranial atherosclerosis (ICAS) and stroke. In hypertensive populations, this association may be pronounced....
Source: Cardiovascular Diabetology - April 19, 2023 Category: Cardiology Authors: Yongle Wang, Tingting Liu, Yanan Li, Kaili Zhang, Haimei Fan, Jing Ren, Juan Li, Yali Li, Xinyi Li, Xuemei Wu, Junhui Wang, Lixi Xue, Xiaolei Gao, Yuping Yan, Gaimei Li, Qingping Liu & hellip; Tags: Research Source Type: research

Endothelial KCa channels: Novel targets to reduce atherosclerosis-driven vascular dysfunction
Front Pharmacol. 2023 Mar 31;14:1151244. doi: 10.3389/fphar.2023.1151244. eCollection 2023.ABSTRACTElevated levels of cholesterol in the blood can induce endothelial dysfunction, a condition characterized by impaired nitric oxide production and decreased vasodilatory capacity. Endothelial dysfunction can promote vascular disease, such as atherosclerosis, where macrophages accumulate in the vascular intima and fatty plaques form that impair normal blood flow in conduit arteries. Current pharmacological strategies to treat atherosclerosis mostly focus on lipid lowering to prevent high levels of plasma cholesterol that induce...
Source: Atherosclerosis - April 17, 2023 Category: Cardiology Authors: O Daniel Vera Heike Wulff Andrew P Braun Source Type: research

Impact of multimorbidity on mortality in HFrEF: Which comorbidities matter most? – An analysis of PARADIGM‐HF and ATMOSPHERE
ConclusionsIn HF, the impact of multimorbidity differed at the individual-patient and population level, depending on the prevalence of and the risk related to each comorbidity, and the interaction between individual comorbidities. Patients with co-existent PAD and stroke were at greatest individual risk whereas, from a population perspective, co-existent CKD and hypertension mattered mostThis article is protected by copyright. All rights reserved.
Source: European Journal of Heart Failure - April 17, 2023 Category: Cardiology Authors: Pooja Dewan, Jo ão P Ferreira, Jawad H Butt, Mark C Petrie, William T Abraham, Akshay S. Desai, Kenneth Dickstein, Lars Køber, Milton Packer, Jean L Rouleau, Simon Stewart, Karl Swedberg, Michael R Zile, Scott D Solomon, Pardeep S Jhund, Tags: Research Article Source Type: research

Design and Rationale of the Home Blood Pressure Telemonitoring Linked with Community Health Workers to Improve Blood Pressure (LINKED-BP) Program
This study is part of the American Heart Association RESTORE (AddREssing Social Determinants TO pRevent hypErtension) Network. This study aims to examine the effect of the LINKED-BP Program on BP reduction and to evaluate the reach, adoption, sustainability, and cost-effectiveness of the intervention.METHODS: Using a hybrid type I effectiveness-implementation design, 600 adults who have elevated BP or untreated stage 1 hypertension without diabetes, chronic kidney disease, history of cardiovascular disease (stroke or coronary heart disease) and age < 65 years will be recruited from 20 primary care practices including co...
Source: American Journal of Hypertension - April 16, 2023 Category: Cardiology Authors: Yvonne Commodore-Mensah Xiaoyue Liu Oluwabunmi Ogungbe Chidinma Ibe Johnitta Amihere Margaret Mensa Seth S Martin Deidra Crews Kathryn A Carson Lisa A Cooper Cheryl R Himmelfarb Source Type: research