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Total 427 results found since Jan 2013.

Prolyl Carboxypeptidase Activity Decline Correlates with Severity and Short-Term Outcome in Acute Ischemic Stroke.
Abstract Prolyl carboxypeptidase (PRCP) is an enzyme associated with cerebrovascular risk factors such as hypertension, diabetes mellitus, obesity and hyperlipidemia. We aim to evaluate the relation between serum PRCP activity and severity, evolution and outcome of acute ischemic stroke. We used a specific RP-HPLC activity assay to measure PRCP activity in serum of 50 stroke patients at admission, and at 24 h, 72 h and 7 days after stroke onset to assess correlations with stroke severity based on the National Institutes of Health Stroke scale score (NIHSS), infarct volume on brain MRI scan, stroke outcome based...
Source: Neurochemical Research - November 5, 2014 Category: Neuroscience Authors: Kehoe K, Brouns R, Verkerk R, Engelborghs S, De Deyn PP, Hendriks D, De Meester I Tags: Neurochem Res Source Type: research

Determinants of post‐stroke cognitive impairment: analysis from VISTA
ConclusionsBesides well‐known determinants of PSCI such as age, stroke severity and the presence of vascular risk factors, also leg paralysis is associated with subsequent of PSCI up to 3 years after stroke.
Source: Acta Neurologica Scandinavica - July 14, 2016 Category: Neurology Authors: F. Arba, T. Quinn, G. J. Hankey, D. Inzitari, M. Ali, K. R. Lees, Tags: Original Article Source Type: research

Determinants of post ‐stroke cognitive impairment: analysis from VISTA
ConclusionsBesides well‐known determinants of PSCI such as age, stroke severity and the presence of vascular risk factors, also leg paralysis is associated with subsequent of PSCI up to 3 years after stroke.
Source: Acta Neurologica Scandinavica - July 12, 2016 Category: Neurology Authors: F. Arba, T. Quinn, G. J. Hankey, D. Inzitari, M. Ali, K. R. Lees, Tags: Original Article Source Type: research

Incidence and predictors of post‐stroke epilepsy
ConclusionsBased on the revised ILAE definition of epilepsy, the incidence of PSE was high in the ESPro. The only independent predictor for PSE was stroke severity.
Source: Acta Neurologica Scandinavica - February 7, 2013 Category: Neurology Authors: Gerhard J. Jungehulsing, Peter U. Heuschmann, Martin Holtkamp, Stefan Schwab, Peter L. Kolominsky‐Rabas Tags: Original Article Source Type: research

Transient ischemic attack and ischemic stroke patients with or without prior stroke
ConclusionsBoth in TIA and IS, vascular risk factors were more common in patients with a history of stroke compared with those without. In contrast to other secondary preventive medications, OAC treatment in the presence of AF was underutilized in patients with a history of stroke.
Source: Acta Neurologica Scandinavica - June 1, 2017 Category: Neurology Authors: F. Buchwald, B. Norrving, J. Petersson Tags: ORIGINAL ARTICLE Source Type: research

CSF-Based Volumetric Imaging Biomarkers Highlight Incidence and Risk Factors for Cerebral Edema After Ischemic Stroke
ConclusionsCerebral edema can be measured in a majority of patients with stroke on follow-up computed tomography using volumetric biomarkers evaluating CSF shifts, including in many without visible midline shift. Edema formation is influenced by clinical and radiographic stroke severity but also by chronic vascular risk factors and contributes to worse stroke outcomes.
Source: Neurocritical Care - May 15, 2023 Category: Neurology Source Type: research

HIV, Predictor of Severity and Mortality of Stroke in CNHU-HKM Cotonou, Benin (P03.178)
CONCLUSIONS: HIV infection is a risk factor of poor outcome during stroke.Disclosure: Dr. Dieu Donné has nothing to disclose. Dr. Constant has nothing to disclose. Dr. Thierry has nothing to disclose. Dr. Dismand has nothing to disclose. Dr. Gilbert has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Dieu Donne, G., Constant, A., Thierry, A., Dismand, H., Gilbert, A. Tags: P03 Cerebrovascular Disease III Source Type: research

Recurrent ischemic stroke is associated with the burden of risk factors
ConclusionHistory of prior ischemic stroke in patients with acute ischemic stroke was associated with the burden of risk factors, atherosclerosis, and atrial fibrillation compared to first‐ever ischemic stroke. This has important implications for secondary preventive treatment.
Source: Acta Neurologica Scandinavica - July 15, 2015 Category: Neurology Authors: A. Moerch‐Rasmussen, A. Nacu, U. Waje‐Andreassen, L. Thomassen, H. Naess Tags: Original Article Source Type: research

UCLA brain-imaging tool and stroke risk test help identify cognitive decline early
UCLA researchers have used a brain-imaging tool and stroke risk assessment to identify signs of cognitive decline early on in individuals who don't yet show symptoms of dementia.   The connection between stroke risk and cognitive decline has been well established by previous research. Individuals with higher stroke risk, as measured by factors like high blood pressure, have traditionally performed worse on tests of memory, attention and abstract reasoning.   The current small study demonstrated that not only stroke risk, but also the burden of plaques and tangles, as measured by a UCLA brain scan, may influence c...
Source: UCLA Newsroom: Health Sciences - April 3, 2013 Category: Universities & Medical Training Source Type: news

Genetic variation at the IGF1 locus shows association to post-stroke outcome and to circulating IGF-I.
CONCLUSION: Variation in rs7136446 of the IGF1 gene associates with post-stroke outcome in relatively young IS patients. Also, rs7136446 associates with s-IGF-I in controls but not in IS, which indicates that IS perturbs a normal genetic impact on s-IGF-I levels. PMID: 24005314 [PubMed - as supplied by publisher]
Source: European Journal of Endocrinology - September 4, 2013 Category: Endocrinology Authors: Aberg ND, Olsson S, Aberg D, Jood K, Stanne TM, Nilsson M, Blomstrand C, Svensson J, Isgaard J, Jern C Tags: Eur J Endocrinol Source Type: research

National registry‐based case–control study: comorbidity and stroke in young adults
ConclusionsIn addition to vascular risk factors, comorbidity (represented by ICD‐10 chapters) was associated with increased risk of stroke in young individuals. The risk of stroke was further increased with the number of diagnosed ICD‐10 chapters.
Source: Acta Neurologica Scandinavica - February 14, 2015 Category: Neurology Authors: E.‐M. Bergman, K. M. Henriksson, S. Åsberg, B. Farahmand, A. Terént Tags: Original Article Source Type: research

Post-stroke depression: Prevalence, associated factors and impact on quality of life among outpatients in a Nigerian hospital
Conclusion: Depression was 20-fold prevalent in stroke survivors compared to controls with stable hypertension, and sevenfold the life-time prevalence reported among adult general population in Nigeria. Furthermore, increased health care bills per month, significant post-stroke disability and poorer QoL indicated survivors more likely to have depression. Findings in this study support the need to pay closer attention to psychosocial needs of stroke survivors to improve well-being. Future longitudinal study on psychosocial burden of stroke is warranted.
Source: South African Journal of Psychiatry - March 21, 2018 Category: Psychiatry Source Type: research

Long ‐term progression of white matter hyperintensities in ischemic stroke
ConclusionsAge and marked WMH at index stroke, but not stroke subtype, predicted long ‐term WMH progression after ischemic stroke before 70 years of age, whereas age and hypertension predicted acquisition of marked WMH in those with no or only mild WMH at baseline.
Source: Acta Neurologica Scandinavica - November 4, 2018 Category: Neurology Authors: Lukas Holmegaard, Christer Jensen, Petra Redfors, Christian Blomstrand, Christina Jern, Katarina Jood Tags: ORIGINAL ARTICLE Source Type: research

Prevalence of stroke survivors in Parakou in northern Benin: A door-to-door community survey.
CONCLUSION: Our study showed a high prevalence of stroke in Titirou and suggested urgent action for prevention. PMID: 32303341 [PubMed - as supplied by publisher]
Source: Revue Neurologique - April 20, 2020 Category: Neurology Tags: Rev Neurol (Paris) Source Type: research

Prevalence of Patent Foramen Ovale in Ischaemic Stroke in Italy: Results of SISIFO Study
Conclusion: If any relationship exists between stroke and PFO, this is more likely in PACI and POCI at a younger age. Our results are consistent with recent findings that underline PFO alone must not be considered a significant independent predictor for stroke; so the presence of PFO alone doesn't permit rushed causal correlations or ‘therapeutic aggressiveness'.Cerebrovasc Dis 2015;39:162-169
Source: Cerebrovascular Diseases - February 26, 2015 Category: Neurology Source Type: research