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Specialty: Neurology
Condition: Inflammatory Bowel Disease

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Total 28 results found since Jan 2013.

Stroke and the risk of gastrointestinal disorders: A Mendelian randomization study
ConclusionThis study provides proof of the presence of a brain–gut axis. Among the complications of ICH, PUD and GERD were more common and associated with the site of hemorrhage.
Source: Frontiers in Neurology - February 21, 2023 Category: Neurology Source Type: research

Young-onset stroke complicating ulcerative colitis
Pract Neurol. 2022 Jan 7:practneurol-2021-003106. doi: 10.1136/practneurol-2021-003106. Online ahead of print.ABSTRACTA 16-year-old girl developed a proximal occlusion of the right middle cerebral artery during a flare-up of acute ulcerative colitis. Although mechanical thrombectomy led to successful middle cerebral artery recanalisation, she required an immediate second thrombectomy due to reocclusion of the same arterial segment. She developed a second ischaemic event 7 days later despite intravenous heparin infusion, later switched to low-molecular-weight heparin, and a third event after 3 days despite the addition of a...
Source: Practical Neurology - January 8, 2022 Category: Neurology Authors: Su Yin Lim Mohamed Sayed Soma Banerjee Neil Rane Dheeraj Kalladka Source Type: research

Prevalence and Predictors of Stroke in Patients with Crohn's Disease: A Nationwide Study
Mounting evidence points to the microbiome as a susceptibility factor for neurological disorders. Patients with Crohn's disease (CD) are at higher ischemic stroke (IS) risk, but no large scale epidemiologic studies have identified risk factors for stroke in this population.
Source: Journal of Stroke and Cerebrovascular Diseases - December 16, 2021 Category: Neurology Authors: Satvir Saggi, Alain Lekoubou, Bruce Ovbiagele Source Type: research

Increased risk of stroke among patients with inflammatory bowel disease: A PRISMA ‐compliant meta‐analysis
ConclusionIBD is a risk factor for stroke. More high-quality large-sample epidemiologic studies about the relationship between IBD and stroke should be further conducted.
Source: Brain and Behavior - May 7, 2021 Category: Neurology Authors: Yao Chen, Xiang Wang Tags: REVIEW Source Type: research

Inflammatory Bowel Disease as a Precondition for Stroke or TIA: A Matter of Crohn's Disease Rather than Ulcerative Colitis
As a chronic systemic inflammation may be associated with an increased risk of vascular events, the aim of the present study was to assess the incidence of stroke and transient ischemic attack (TIA) in patients with inflammatory bowel disease over a period of 15 years.
Source: Journal of Stroke and Cerebrovascular Diseases - April 14, 2021 Category: Neurology Authors: Christian Tanislav, Kathleen Trommer, Christian Labenz, Karel Kostev Source Type: research

Giant Vertebrobasilar Fusiform Aneurysm Mass Effect Heralds Rapid in Situ Thrombosis and Ischemic Stroke in the Setting of Ulcerative Colitis
Here we describe a case of brainstem infarction secondary to rapid thrombus formation in a giant vertebrobasilar fusiform aneurysm (GVBFA) that was preceded clinically by several months of headaches and dizziness initially attributable to mass effect. Less than a month after initial identification of the aneurysm, a large partially-occluding thrombus formed leading to infarction of the brainstem. Interestingly, this patient also had ulcerative colitis, which has been associated with acquired hypercoagulability.
Source: Journal of Stroke and Cerebrovascular Diseases - February 10, 2021 Category: Neurology Authors: Keith J. Kincaid, Ju Yu, Franklin D. Echevarria, Alexis N. Simpkins Tags: Case Report Source Type: research

Association Between Chronic Inflammatory Diseases and Stroke-Associated Pneumonia – An Epidemiological Study
This study assessed the relationship between chronic inflammatory diseases and stroke-associated pneumonia (SAP).
Source: Journal of Stroke and Cerebrovascular Diseases - January 19, 2021 Category: Neurology Authors: Layne Dylla, Paco S. Herson, Sharon N. Poisson, John D. Rice, Adit A. Ginde Source Type: research

Stroke Dysbiosis Index (SDI) in Gut Microbiome Are Associated With Brain Injury and Prognosis of Stroke
Conclusions: We developed an index to measure gut microbiota dysbiosis in stroke patients; this index was significantly correlated with patients' outcome and was causally related to outcome in a mouse model of stroke. Our model facilitates the potential clinical application of gut microbiota data in stroke and adds quantitative evidence linking the gut microbiota to stroke. Introduction Ischemic stroke imposes a heavy burden on society, with 24.9 million cases worldwide (1). Although intravenous thrombolysis and endovascular treatment greatly improve some patients' prognosis, the prognosis for most pa...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Bidirectional gut-brain-microbiota axis as a potential link between inflammatory bowel disease and ischemic stroke
Emerging evidence suggests that gut-brain-microbiota axis (GBMAx) may play a pivotal role linking gastrointestinal and neuronal disease. In this review, we summarize the latest advances in studies of GBMAx in ...
Source: Journal of Neuroinflammation - December 11, 2018 Category: Neurology Authors: Liang Zhao, Qiutang Xiong, Creed M. Stary, Omer Kamal Mahgoub, Yingze Ye, Lijuan Gu, Xiaoxing Xiong and Shengmei Zhu Tags: Review Source Type: research

Paradoxical Cerebral Embolism after Gastrointestinal Endoscopy in a Patient with Crohn's Disease
We describe a patient with Crohn's disease who developed paradoxical cerebral embolism after GE. Both an unstable venous thrombus in the superior vena cava and RLS through patent foramen ovale were thought to be responsible for the stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - February 28, 2018 Category: Neurology Authors: Hajime Ikenouchi, Naoto Sugeno, Takaaki Nakamura, Junpei Kobayashi, Ryuji Oshima, Hiroshi Kuroda, Masashi Aoki Tags: Case Studies Source Type: research

Huge Free-Floating Thrombus in the Internal Carotid Artery
A 70-year-old male patient presented with very short recurrent speech difficulty and left-sided monocular transient visual loss. The patient was diagnosed with Crohn's disease and had hemicolectomy due to obstruction 10 years ago. He also had a history of coronary artery disease, hypertension, left femoral vein thrombosis, and 50-pack-year smoking. He had no stroke attack before. He was taking regularly dual antiplatelet therapy and azathioprine.
Source: Journal of Stroke and Cerebrovascular Diseases - August 22, 2017 Category: Neurology Authors: Uygur Tanriverdi, Osman Kizilkilic, Birsen Ince Tags: Letter to the Editor Source Type: research

Clinical Reasoning: Acute onset facial droop in a 36-year-old pregnant woman
A 36-year-old woman, G1P0, 22 weeks pregnant, presented to the emergency department for evaluation of acute onset facial droop. Her medical history included ulcerative colitis, primary sclerosing cholangitis, and heterozygosity for the prothrombin G20210A mutation. She was on 10,000 units of subcutaneous heparin twice daily for a previous deep vein thrombosis secondary to her prothrombin mutation; she was noncompliant with prescribed aspirin.
Source: Neurology - June 12, 2017 Category: Neurology Authors: George, I. C., Youn, T. S., Marcolini, E. G., Greer, D. M. Tags: Other cerebrovascular disease/ Stroke, Autoimmune diseases, Critical care, All Demyelinating disease (CNS) RESIDENT AND FELLOW SECTION Source Type: research

Prevalence of Ischemic Stroke in Cohort of Ulcerative Colitis Patients (P3.256)
Conclusions:In our cohort of ulcerative colitis patients, prevalence of ischemic stroke was 6000 per 100,000 which is not significantly different than the general population. However, in the under 60 age group prevalence of ischemic stroke is twice as that of the general population. Further population based cohort studies are needed to elucidate actual incidence in this high-risk group for early intervention.Study Supported by: No funding.Disclosure: Dr. Horta has nothing to disclose. Dr. Tore has nothing to disclose. Dr. Kent has nothing to disclose. Dr. Ezzeddine has received personal compensation for activities with Air...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Horta, E., Tore, H., Kent, N., Ezzeddine, M., Streib, C., Reshi, R. Tags: Cerebrovascular Disease Epidemiology Source Type: research