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Specialty: Internal Medicine
Condition: Hemorrhagic Stroke

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Total 363 results found since Jan 2013.

Cardiovascular Outcomes in Patients Initiating First-Line Treatment of Type 2 Diabetes With Sodium-Glucose Cotransporter-2 Inhibitors Versus Metformin : A Cohort Study
CONCLUSION: As first-line T2D treatment, initiators receiving SGLT-2i showed a similar risk for MI/stroke/mortality, lower risk for HHF/mortality and HHF, and a similar safety profile except for an increased risk for genital infections compared with those receiving metformin.PRIMARY FUNDING SOURCE: Brigham and Women's Hospital and Harvard Medical School.PMID:35605236 | DOI:10.7326/M21-4012
Source: Annals of Internal Medicine - May 23, 2022 Category: Internal Medicine Authors: HoJin Shin Sebastian Schneeweiss Robert J Glynn Elisabetta Patorno Source Type: research

Red cell distribution width: a novel predictive biomarker for stroke risk after transient ischaemic attack
CONCLUSIONS: The early determination of RDW is a promising, rapid, easy and inexpensive biomarker to predict the subsequent stroke in TIA patients, especially for IS. KEY MESSAGESThe most important result of our study is to show that (1) the higher RDW, the earlier the stroke onset and (2) RDW ≥13.95% has a 2.52-fold risk of ischaemic stroke in TIA patients, and RDW ≥12.85% has a 1.51-fold risk of haemorrhagic stroke.As an economic and accessible hematological marker, baseline RDW may serve as a useful biomarker for risk stratification in TIA patients.PMID:35471128 | PMC:PMC9045760 | DOI:10.1080/07853890.2022.2059558
Source: Annals of Medicine - April 26, 2022 Category: Internal Medicine Authors: Ke-Hang Xie Ling-Ling Liu Yun-Ru Liang Chu-Yin Su Hua Li Run-Ni Liu Qing-Qing Chen Jia-Sheng He Yong-Kun Ruan Wang-Kai He Source Type: research

Non-Hodgkin's lymphoma revealed by a cerebral vascular stroke: A case report
We report the case of a 75-year-old patient admitted to the emergency room following a classic hemorrhagic stroke. The CT scan showed a hyperdense tumor-like process with perilesional edema, the diagnosis reinforced by (MRI). The patient underwent macroscopically total surgical excision and the anatomo pathological examination concluded a diffuse non-Hodgkin's B large cell lymphoma. The follow up was marked by a clear clinical improvement. Primary cerebral lymphomas can be polymorphic, so this diagnosis should always be kept in mind during stroke manifestations. This case illustrates the diagnostic difficulty of this rare ...
Source: Annals of Medicine - April 7, 2022 Category: Internal Medicine Authors: Oufaa Jamal Marouane Makhchoune Yassin Tahrir Khadija El Guettabi Abdelhakim Lakhdar Source Type: research

Craniocervical Artery Dissections: A Concise Review for Clinicians
Craniocervical artery dissection (CAD), although uncommon, can affect the young and lead to devastating complications, including stroke and subarachnoid hemorrhage. It starts with a tear in the intima of a vessel with subsequent formation of an intramural hematoma. Most CAD occurs spontaneously or after minor trauma. Patients with CAD may exhibit isolated symptoms of an underlying subclinical connective tissue disorder or have a clinically diagnosed connective tissue disorder. Emergent evaluation and computed tomography angiography or magnetic resonance imaging/angiography of the head and neck are required to screen for and to diagnose CAD.
Source: Mayo Clinic Proceedings - April 1, 2022 Category: Internal Medicine Authors: Zafer Keser, James F. Meschia, Giuseppe Lanzino Tags: Concise review Source Type: research

Ferroptosis in oligodendrocyte progenitor cells mediates white matter injury after hemorrhagic stroke
Cell Death & Disease, Published online: 23 March 2022; doi:10.1038/s41419-022-04712-0Ferroptosis in oligodendrocyte progenitor cells mediates white matter injury after hemorrhagic stroke
Source: Cell death and disease - March 23, 2022 Category: Internal Medicine Authors: Danmin Shen Weihua Wu Jing Liu Ting Lan Zhongnan Xiao Kaiyuan Gai Liye Hu Zhaoli Luo Chao Wei Xiaotong Wang Yabin Lu Yamei Wang Chenguang Zhang Peipei Wang Zhentao Zuo Fei Yang Qian Li Source Type: research

Visit-to-visit blood pressure variability and the risk of stroke in the Netherlands: A population-based cohort study
by Alis Heshmatollah, Yuan Ma, Lana Fani, Peter J. Koudstaal, M. Arfan Ikram, M. Kamran Ikram BackgroundApart from blood pressure level itself, variation in blood pressure has been implicated in the development of stroke in subgroups at high cardiovascular risk. We determined the association between visit-to-visit blood pressure variability and stroke risk in the general population, taking into account the size and direction of variation and several time intervals prior to stroke diagnosis. Methods and findingsFrom 1990 to 2016, we included 9,958 stroke-free participants of the population-based Rotterdam Study in the Nethe...
Source: PLoS Medicine - March 17, 2022 Category: Internal Medicine Authors: Alis Heshmatollah Source Type: research

Computed tomography and clinical parameters predict intracerebral hemorrhage expansion
This study aimed to evaluate the association of imaging signs, and to establish a predictive model through selecting highly relevant imaging signs in combination with clinical parameters for hematoma expansion. Intracerebral Hemorrhage (ICH) patients who received 2 consecutive noncontrast computed tomography scans were examined and recruited through January 2014 to December 2020. Demographic information and clinical characteristics were collected. Two experienced radiologists reviewed baseline noncontrast computed tomography images to assess the imaging characteristics. Correlation analysis was analyzed with Pearson and...
Source: Medicine - March 4, 2022 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Efficacy and safety of rt-PA intravenous thrombolysis in patients with wake-up stroke: A meta-analysis
Background : Recombinant tissue plasminogen activator (rt-PA) is one of the most effective therapies for patients with acute ischemic stroke. However, wake-up stroke (WUS) is typically excluded from intravenous thrombolytic therapy because of the unclear time of symptom onset. Therefore, we aimed to assess the efficacy and safety of rt-PA intravenous thrombolysis in patients with WUS by meta-analysis. Methods : We completed a systematic literature search of PubMed, Embase, the Cochrane Library, and SinoMed and included relevant studies of WUS patients covering rt-PA thrombolysis and nonthrombolysis (published fr...
Source: Medicine - February 18, 2022 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

Delayed gait recovery by resolution of limb-kinetic apraxia in a chronic hemiparetic stroke patient: A case report
Rationale: This paper reports on a chronic hemiparetic stroke patient who showed delayed gait recovery due to resolution of limb-kinetic apraxia (LKA). Patient concerns: A 49-year-old man underwent comprehensive rehabilitation at a local rehabilitation hospital since 3 weeks after spontaneous intracerebral haemorrhage. However, he could not walk independently because of severe motor weakness in his right leg until 19 months after the onset. Diagnosis: At the beginning of rehabilitation at our hospital (19 months after onset), we thought that he had the neurological potential to walk independently beca...
Source: Medicine - January 28, 2022 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Associations of Serum Testosterone and Sex Hormone-Binding Globulin With Incident Cardiovascular Events in Middle-Aged to Older Men
CONCLUSION: Men with lower total testosterone concentrations were not at increased risk for MI, stroke, HF, or MACE. Calculated free testosterone may be associated with risk for MACE. Men with lower SHBG concentrations have higher risk for MI but lower risk for IS and HF, with causality to be determined.PRIMARY FUNDING SOURCE: Western Australian Health Translation Network, Medical Research Future Fund, and Lawley Pharmaceuticals.PMID:34958606 | DOI:10.7326/M21-0551
Source: Annals of Internal Medicine - December 27, 2021 Category: Internal Medicine Authors: Bu B Yeap Ross J Marriott Leen Antonio Suchitra Raj Girish Dwivedi Christopher M Reid Bradley D Anawalt Shalender Bhasin Adrian S Dobs David J Handelsman Graeme J Hankey Robin Haring Alvin M Matsumoto Paul E Norman Terence W O'Neill Claes Ohlsson Eric S O Source Type: research