• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Hospital Course, Confounders, and Medications
This article outlines the process of the development of common data elements for hospital course, confounders, and medications to streamline definitions and variables to collect for clinical studies of DoC.
Source: Neurocritical Care - August 23, 2023 Category: Neurology Source Type: research

Delirium detection using wearable sensors and machine learning in patients with intracerebral hemorrhage
ConclusionsWe found that actigraphy in conjunction with machine learning models improves clinical detection of delirium in patients with stroke, thus paving the way to make actigraph-assisted predictions clinically actionable.
Source: Frontiers in Neurology - June 9, 2023 Category: Neurology Source Type: research

Sex-dependent association analysis between serum uric acid and spontaneous hemorrhagic transformation in patients with ischemic stroke
ConclusionsHigher serum UA was independently associated with a higher occurrence of spontaneous HT in male patients who were admitted within 24 h after the stroke onset without receiving reperfusion therapy.
Source: Frontiers in Neurology - March 3, 2023 Category: Neurology Source Type: research

Early Intracranial Hemorrhage Predicts Poor Clinical Outcome in Community-Acquired Bacterial Meningitis
ConclusionEarly cerebral hemorrhage (ECHO) is a potential prognostic marker for clinicians confronted with decision-making in patients who are critically ill with community-acquired bacterial meningitis.
Source: Frontiers in Neurology - June 16, 2022 Category: Neurology Source Type: research

Procedural and Methodological Quality in Preclinical Stroke Research –A Cohort Analysis of the Rat MCAO Model Comparing Periods Before and After the Publication of STAIR/ARRIVE
In conclusion, the frequency of periinterventional monitoring has decreased over time. Some general methodological quality aspects, however, partially have increased. CBF measurement–the gold standard for ischemia verification-was applied rarely. Despite the growing recognition of current guidelines such as STAIR and ARRIVE (both widely approved in 2019) reporting, methods and procedures mostly do not follow these guidelines. These deficits may contribute to the translational failure of preclinical stroke research in search for neuroprotective therapies.
Source: Frontiers in Neurology - May 30, 2022 Category: Neurology Source Type: research

Predictive Factors for the Need of Tracheostomy in Patients With Large Vessel Occlusion Stroke Being Treated With Mechanical Thrombectomy
Conclusions: Patients with LVOS undergoing MT are at high risk to require TS if extubation after the intervention fails, DH is needed, and severe infectious complications occur in the acute phase after ischemic stroke. These factors are likely to be useful for the indication and timing of TS to reduce overall sedation and shorten ICU length of stay.
Source: Frontiers in Neurology - November 26, 2021 Category: Neurology Source Type: research

Multi-Center Randomized Phase II Clinical Trial on Remote Ischemic Conditioning in Acute Ischemic Stroke Within 9 Hours of Onset in Patients Ineligible to Recanalization Therapies (TRICS-9): Study Design and Protocol
Conclusion: RIC in combination with recanalization therapies appears to add no clinical benefit to patients, but whether it is beneficial to those that are not candidates for recanalization therapies is still to be demonstrated. TRICS-9 has been developed to elucidate this issue.Clinical Trial Registration:ClinicalTrials.gov, identifier: NCT04400981.
Source: Frontiers in Neurology - November 3, 2021 Category: Neurology Source Type: research

Stroke Seasonality and Weather Association in a Middle East Country: A Single Tertiary Center Experience
Conclusions: In Riyadh, Saudi Arabia, our study found no impact of weather or seasonal variations on stroke incidence, hospital course, or outcomes. However, our findings warrant further research in different country regions.
Source: Frontiers in Neurology - October 18, 2021 Category: Neurology Source Type: research

Anticoagulation in Acute Neurological Disease
Semin Neurol 2021; 41: 530-540 DOI: 10.1055/s-0041-1733793While anticoagulation and its reversal have been of clinical relevance for decades, recent academic and technological advances have expanded the repertoire of its application in neurological disease. The advent of direct oral anticoagulants provides effective, mechanistically elegant, and relatively safer therapeutic options than warfarin for eligible patients at risk for neurological sequelae of prothrombotic states, particularly given the recent availability of corresponding reversal agents. In this review, we examine the provenance, indications, safety, and rever...
Source: Seminars in Neurology - October 7, 2021 Category: Neurology Authors: Sasannejad, Cina Sheth, Kevin N. Tags: Review Article Source Type: research

A Systematic Review of the Predictive Value of Plasma D-Dimer Levels for Predicting Stroke Outcome
Conclusion: The study provides preliminary evidence concerning the capacity of plasma D-dimer levels for predicting functional outcomes and mortality following stroke and reports that higher D-dimer levels of are associated with poorer functional outcomes and higher mortality.
Source: Frontiers in Neurology - July 6, 2021 Category: Neurology Source Type: research

Drip-and-Ship Model for Thrombectomy in Stroke Patients with Large-Vessel Occlusion
Conclusions: The “drip-and-ship” model has the potential to be a feasible model for patients with LVO in the anterior circulation to undergo endovascular treatment. Further large-scale prospective studies are warranted to confirm these findings.Eur Neurol
Source: European Neurology - March 5, 2021 Category: Neurology Source Type: research

Changed pattern of hospital admission in stroke during COVID-19 pandemic period in Iran: a retrospective study
ConclusionsThe present study provided new pieces of evidence regarding the changed pattern of hospital admission in stroke especially the possible reasons for its decline.
Source: Neurological Sciences - January 4, 2021 Category: Neurology Source Type: research

Cerebrovascular Disease in Patients with COVID-19: A Review of the Literature and Case Series
COVID-19 has been associated with a hypercoagulable state causing cardiovascular and neurovascular complications. To further characterize cerebrovascular disease (CVD) in COVID-19, we review the current literature of published cases and additionally report the clinical presentation, laboratory and diagnostic testing results of 12 cases with COVID-19 infection and concurrent CVD from two academic medical centers in Houston, TX, USA, between March 1 and May 10, 2020. To date, there are 12 case studies reporting 47 cases of CVD in COVID-19. However, only 4 small case series have described the clinical and laboratory findings ...
Source: Case Reports in Neurology - June 11, 2020 Category: Neurology Source Type: research

Thrombectomy Outcomes in Acute Ischemic Stroke due to Middle Cerebral Artery M2 Occlusion with Stent Retriever versus Aspiration: A Multicenter Experience
Conclusion: Utilization of a newer-generation pump aspiration catheter compared to a stent retriever resulted in similar outcomes, but worse outcomes were seen with the manual aspiration technique. These findings need to be confirmed with a large randomized trial utilizing stent retrievers and newer-generation pump aspiration systems.Intervent Neurol 2019;8:180 –186
Source: Interventional Neurology - June 18, 2019 Category: Neurology Source Type: research

Pages: 1  2  3  4  5  6  7