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Condition: Hemorrhagic Stroke
Education: Academia

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Total 250 results found since Jan 2013.

Endovascular therapy versus medical treatment for symptomatic intracranial artery stenosis.
CONCLUSIONS: This systematic review provides moderate-quality evidence showing that ET, compared with CMT, in people with recent symptomatic severe intracranial atherosclerotic stenosis probably does not prevent recurrent stroke and appears to carry an increased hazard. The impact of delayed ET intervention (more than three weeks after a qualifying event) is unclear and may warrant further study. PMID: 32789891 [PubMed - in process]
Source: Cochrane Database of Systematic Reviews - August 10, 2020 Category: General Medicine Authors: Wang T, Luo J, Wang X, Yang K, Jadhav V, Gao P, Ma Y, Zhao N, Jiao L Tags: Cochrane Database Syst Rev Source Type: research

Extensive Workup for Embolic Sources in Lacunar Strokes: Prevalence in an Academic Setting (P1.043)
CONCLUSIONS: Lacunar strokes represent a substantial fraction of the ischemic strokes admitted in this urban hospital setting. These patients typically receive extensive work-up for thromboembolic sources similar to that applied to large artery strokes. Examination of clinical features and outcomes of lacunar stroke, and of the clinical utility of the extensive imaging, is warranted to guide best clinical practices.Disclosure: Dr. Wang has nothing to disclose. Dr. Choi has nothing to disclose. Dr. Gallardo has nothing to disclose. Dr. Nwaneri has nothing to disclose. Dr. Brorson has received personal compensation for activ...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Wang, Y., Choi, Y., Gallardo, J., Nwaneri, I., Brorson, J. Tags: Cerebrovascular Disease and Interventional Neurology: The Spectrum of Small Vessel Cerebrovascular Disease Source Type: research

E-219 Direct vs indirect revascularization for moyamoya: a large multicenter study
ConclusionSince both modalities showed comparable rates of overall total strokes, both modalities of revascularization can be performed depending on the patient’s risk assessment.Abstract E-219 Table 1Direct Indirect Effect variable Value (95% confidence interval) P-value Primary Outcome Symptomatic stroke, n (%) 23/198 (11.6) 19/198 (9.6) Odds ratio 1.238 (0.651 - 2.354) 0.514 Secondary Outcomes Symptomatic ischemic stroke, n (%) 23/198 (11.6) 16/198 (8.1) Odds ratio 1.495 (0.764 - 2.924) 0.240 Symptomatic hemorrhagic stroke, n (%) 0/198 (0) 3/198 (1.5) –– –– 0.248 Peri-operative stroke,...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: El Naamani, K., Chen, C., Jabre, R., Saad, H., Grissberg, J., Dmytriw, A., Patel, A., Khorasanizadeh, M., Ogilvy, C., Thomas, A., Monteiro, A., Siddiqui, A., Cortez, G., Hanel, R., Porto, G., Spiotta, A., Piscopo, A., Hasan, D., Ghorbani, M., Weinberg, J. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-138 Intracerebral hemorrhage in patients transferred for mechanical thrombectomy
ConclusionsIn a large series of stroke patients being specifically transferred for mechanical thrombectomy, the rate of ICH on arrival to the thrombectomy hospital was 1.2%. In less than 50% of those cases the decision to forgo intervention was related to the ICH finding. The results of our study adds to the concerns that repeat imaging delays treatment by demonstrating that the incidence of ICH is low, which may warrant reconsideration of current stroke workflows for large vessel occlusion transfers.Disclosures Y. Radaideh: None. K. Joshi: None. M. Chen: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Radaideh, Y., Joshi, K., Chen, M. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

Delirium detection using wearable sensors and machine learning in patients with intracerebral hemorrhage
ConclusionsWe found that actigraphy in conjunction with machine learning models improves clinical detection of delirium in patients with stroke, thus paving the way to make actigraph-assisted predictions clinically actionable.
Source: Frontiers in Neurology - June 9, 2023 Category: Neurology Source Type: research

Patient Safety and Outcomes after Thrombolysis within a 4.5 Hour Window Via Telestroke Network (P03.179)
CONCLUSIONS: This study confirms that IV thrombolysis within a 4.5 hour window can be performed safely and effectively through a telemedicine network with outcomes similar to what can be obtained treating patients directly at an academic stroke center.Disclosure: Dr. Suwatcharangkoon has nothing to disclose. Dr. Reynolds has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Suwatcharangkoon, S., Reynolds, P. Tags: P03 Cerebrovascular Disease III Source Type: research

Recombinant Tissue Plasminogen Activator Induces Neurological Side Effects Independent on Thrombolysis in Mechanical Animal Models of Focal Cerebral Infarction: A Systematic Review and Meta-Analysis
Conclusions This meta-analysis reveals rtPA can lead to neurological side effects besides thrombolysis in mechanical animal stroke, which may account for clinical exacerbation for stroke patients that do not achieve vascular recanalization with rtPA.
Source: PLoS One - July 6, 2016 Category: Biomedical Science Authors: Mei-Xue Dong Source Type: research

Decreased CSF Levels of ß-Amyloid in Patients With Cortical Superficial Siderosis
Conclusions: Our results demonstrate that the presence and extent of cSS are associated with reduced CSF ß-amyloid 42 levels. Further studies are needed to investigate the underlying mechanisms of this association. Introduction Cerebral amyloid angiopathy (CAA)—characterized by the deposition of ß-amyloid in the walls of leptomeningeal vessels—is a common cerebral small vessel disease and a major cause of intracerebral hemorrhage in the elderly (1–3). Furthermore, it has become evident that CAA is associated with cognitive impairment (4). Specifically, it has been shown that ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Cerebrovascular Disease in Patients with COVID-19: A Review of the Literature and Case Series
COVID-19 has been associated with a hypercoagulable state causing cardiovascular and neurovascular complications. To further characterize cerebrovascular disease (CVD) in COVID-19, we review the current literature of published cases and additionally report the clinical presentation, laboratory and diagnostic testing results of 12 cases with COVID-19 infection and concurrent CVD from two academic medical centers in Houston, TX, USA, between March 1 and May 10, 2020. To date, there are 12 case studies reporting 47 cases of CVD in COVID-19. However, only 4 small case series have described the clinical and laboratory findings ...
Source: Case Reports in Neurology - June 11, 2020 Category: Neurology Source Type: research

Protocol for a prospective, multicentre registry study of stenting for symptomatic intracranial artery stenosis in China
This study aims to evaluate the safety and efficacy of endovascular stenting for patients with symptomatic intracranial artery stenosis and poor collaterals in China and to identify the characteristics of the population that would benefit the most from endovascular stenting in Chinese patients. Methods and analysis This multicentre prospective registry study will involve 20 stroke centres in China, and plans to recruit 300 patients into the registry. Patients with ≥70% stenosis and symptomatic intracranial atherosclerotic disease caused by hypoperfusion combined with poor collaterals who met the inclusion criteria and ...
Source: BMJ Open - August 8, 2014 Category: Journals (General) Authors: Wang, Y., Miao, Z., Wang, Y., Zhao, X., Gao, P., Liu, L., Wang, F., Liu, Y., Ma, N., Xu, Z., Mo,, D., Gao, F., China registry study group Tags: Open access, Cardiovascular medicine, Medical management, Neurology, Surgery Protocol Source Type: research

Pineal Apoplexy With Cerebral Infarction (P1.033)
CONCLUSIONS:Although it appears that the infarcts were caused by the apoplexy due to their temporal progression, we conclude that pineal apoplexy was unlikely to cause the patient’s stroke and that the potential culprit of both events was a proximal source such as a cardiac or aortic thromboembolism.Disclosure: Dr. Truong has nothing to disclose. Dr. Young has nothing to disclose. Dr. Naderi has nothing to disclose. Dr. Brizuela has nothing to disclose. Dr. Handwerker has nothing to disclose. Dr. Al-Khoury has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Truong, A., Young, M., Naderi, N., Brizuela, A., Handwerker, J., Al-Khoury, L. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

E-050 last chance carotid stenting: treatment and outcomes of carotid artery stenting in very high risk patients
ConclusionsOur study indicates that CAS can be safely performed in patients considered too high-risk for CEA and who were referred to our center as such by their physicians.DisclosuresJ. Lozano: None. F. Massari: None. C. Brooks: None. M. Perras: None. M. Howk: None. M. Gounis: 1; C; NIH, Philips Healthcare, Covidien/eV3 Neurovascular, Codman Neurovascular, Stryker Neurovascular, Wyss Institute, Tay Sachs Foundation. 2; C; Stryker Neurovascular. N. Henninger: None. A. Wakhloo: 1; C; Phillips Healthcare Medical. 2; C; Stryker. 3; C; Harvard Postgraduate Course, Miami Baptist Vascular Institute. A. Puri: 1; C; Stryker. 2; C; Codman, Covidien.
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Lozano, J., Massari, F., Brooks, C., Perras, M., Howk, M., Gounis, M., Henninger, N., Wakhloo, A., Puri, A. Tags: SNIS 12th Annual Meeting Electronic Poster Abstracts Source Type: research

Local Experience with a new retrievable stent (ERIC) in academic Center (P5.269)
Conclusions:In this study, the use of new ERIC retrieval device was technically feasible, safe, and effective in acute ischemic stroke with large-vessel occlusionDisclosure: Dr. Alshaer has nothing to disclose. Dr. Alturkustani has nothing to disclose. Dr. Khoja has nothing to disclose. Dr. Almekhlafi has nothing to disclose. Dr. Ayoub has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: AlShaer, D., Alturkustani, A., Khoja, A., Almekhlafi, M., Ayoub, O. Tags: Acute Cerebrovascular Interventional Therapies Source Type: research

Comparison of Triflusal with Aspirin in the Secondary Prevention of Atherothrombotic Events; Α Randomised Clinical Trial.
CONCLUSION: The efficacy of triflusal in the secondary prevention of vascular events is similar to aspirin when administered for 12 months. Importantly, triflusal significantly reduced the incidence of ΜΙ and showed a better safety profile compared with aspirin. (ASpirin versus Triflusal for Event Reduction In Atherothrombosis Secondary prevention, ASTERIAS trial; Clinical Trials.gov Identifier: NCT02616497). PMID: 29866011 [PubMed - as supplied by publisher]
Source: Current Vascular Pharmacology - June 4, 2018 Category: Drugs & Pharmacology Authors: Kalantzi KI, Ntalas IV, Chantzichristos VG, Tsoumani ME, Adamopoulos D, Asimakopoulos C, Bourdakis A, Darmanis P, Dimitriadou A, Gkiokas S, Ipeirotis K, Kitikidou K, Klonaris I, Kostaki A, Logothetis D, Mainas K, Mais T, Maragiannis A, Martiadou K, Mavron Tags: Curr Vasc Pharmacol Source Type: research

A Chinese Family With Adult-Onset Leigh-Like Syndrome Caused by the Heteroplasmic m.10191T > C Mutation in the Mitochondrial MTND3 Gene
Conclusion The m.10191T>C mutation in the mtDNA of the complex I (CI) subunit of MTND3 results in the substitution of a highly conserved amino acid (p.Ser45Pro) within the ND3 protein, leading to CI dysfunction through impaired enzyme catalysis rather than impaired stability or assembly, causing a broad clinical spectrum of disorders (26). Patients with the m.10191T>C mutation are rare. In the present study, we report on a family of patients with the extremely rare adult-onset Leigh-like syndrome with the m.10191T>C mutation. Including the two patients from our reported family, the m.10191T...
Source: Frontiers in Neurology - April 17, 2019 Category: Neurology Source Type: research