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Condition: Ischemic Stroke
Procedure: Transplants

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Total 1030 results found since Jan 2013.

Gut Flora Mediates the Rapid Tolerance of Electroacupuncture on Ischemic Stroke by Activating Melatonin Receptor through Regulating Indole-3-Propionic Acid
This study aimed to clarify the mechanisms of action of treatments of cerebral ischemic stroke from the perspective of gut microecology. We used a mouse model and cell cultures to investigate the effects of EA on the intestinal microflora in mice models of middle cerebral artery occlusion (MCAO) and the mechanisms underlying the antioxidant activities of metabolites. Fecal microbiota transplantation (FMT) was used to validate the roles of gut microbiota. Metabolomic analysis was performed to characterize the metabolic profile differences between the mice in the EA + MCAO and MCAO groups. Gavaging with feces relieved brain ...
Source: The American Journal of Chinese Medicine - April 27, 2022 Category: Complementary Medicine Authors: Shan Li Xiaoyong Zhao Feihong Lin Xuqing Ni Xia Liu Chang Kong Xinyu Yao Yunchang Mo Qinxue Dai Junlu Wang Source Type: research

Comparing short ‐term/long‐term outcomes of heart transplants that occur inside and outside of normal working hours
ConclusionThere was no significant difference in clinical outcomes between heart transplants taking place inside or outside of working hours. A high quality of care can be provided for heart transplant patients even during after hours.
Source: ESC Heart Failure - April 23, 2022 Category: Cardiology Authors: Hidefumi Nishida, Christopher Salerno, David Onsager, Tae Song, Ann Nguyen, Jonathan Grinstein, Bow Chung, Bryan Smith, Sara Kalantari, Nitasha Sarswat, Gene Kim, Sean Pinney, Valluvan Jeevanandam, Takeyoshi Ota Tags: Original Article Source Type: research

Various detailed characteristics of a new enhanced neurotrophic factor secreting rat derived bone marrow mesenchymal stem cells and its preliminary application in rat models of ischemic stroke
Exp Cell Res. 2022 Apr 15:113140. doi: 10.1016/j.yexcr.2022.113140. Online ahead of print.ABSTRACTBecause MSC-NTF has a higher ability to secrete neurotrophic factors, it may have a greater potential than ordinary MSC in clinical applications. At present, research on MSC-NTF mainly focuses on clinical aspects, but its basic research is relatively few. In particular, the research on the comprehensive and detailed characteristics of MSC-NTF is missing. And its in vivo research in animals is also rare. Since the transplantation of human-derived MSC-NTF into rats is cross-species, its survival in the rat and the therapeutic ef...
Source: Experimental Cell Research - April 18, 2022 Category: Cytology Authors: Fenjun Jiang Hui Zhou Yanwen Cheng Zi He Peipei Meng Kaizhou Sun Peishen Wang Xinye Han Lu Wang Mingbin Yang Ningjian Jiang Yang Liu Chunmei Yuan Qing Yang Yihua An Source Type: research

Preclinical Studies of Neural Stem/Progenitor Cell Therapy for Ischemic Stroke: A Systematic Review
CONCLUSION: Most of the preclinical studies reported statistically significant effects and very few adverse reactions. Transplantation of NSPCs for ischemic stroke still needs to be optimized for several key factors. A standardized treatment outcome assessment could ease the translation of evidence in clinical settings.PMID:35410620 | DOI:10.2174/1574888X17666220410221905
Source: Cell Research - April 12, 2022 Category: Cytology Authors: Mengze Zhang Kan Wang Chunran Xue Chong Xie Ze Wang Yaying Song Haojun Yu Yong Hao Yangtai Guan Source Type: research