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Condition: Ischemic Stroke
Procedure: Perfusion
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Total 2383 results found since Jan 2013.
Stroke and Neurogenesis: Bridging Clinical Observations to New Mechanistic Insights from Animal Models
AbstractStroke was the 2nd leading cause of death and a major cause of morbidity. Unfortunately, there are limited means to promote neurological recovery post-stroke, but research has unearthed potential targets for therapies to encourage post-stroke neurogenesis and neuroplasticity. The occurrence of neurogenesis in adult mammalian brains, including humans, was not widely accepted until the 1990s. Now, adult neurogenesis has been extensively studied in human and mouse neurogenic brain niches, of which the subventricular zone of the lateral ventricles and subgranular zone of the dentate gyrus are best studied. Numerous oth...
Source: Translational Stroke Research - December 3, 2022 Category: Neurology Source Type: research
Estimated pulse-wave velocity predicts survival in patients requiring extracorporeal membrane oxygenation
CONCLUSIONS: ePWV is a promising marker for risk-stratification in ECMO patients. Further investigation is required to better delineate the role of arterial health assessment in disease trajectory and strengthen the validity of AS as a marker of interest in medical and surgical management.PMID:36419384 | DOI:10.1177/02676591221141963
Source: Perfusion - November 24, 2022 Category: Cardiovascular & Thoracic Surgery Authors: Mohsyn I Malik Dave Nagpal Source Type: research
Cerebral perfusion imaging predicts final infarct volume after basilar artery thrombectomy
Cerebral perfusion imaging may be used to identify the ischemic core in acute ischemic stroke (AIS) patients with a large vessel occlusion of the anterior circulation; however, perfusion parameters that predict the ischemic core in AIS patients with a basilar artery occlusion (BAO) are poorly described. We determined which cerebral perfusion parameters best predict the ischemic core after successful endovascular thrombectomy (EVT) in BAO patients.
Source: Journal of Stroke and Cerebrovascular Diseases - November 23, 2022 Category: Neurology Authors: Nicole Yuen, Michael Mlynash, Andrea O'Riordan, Maarten Lansberg, Soren Christensen, Carlo W. Cereda, Giovanni Bianco, Dan-Victor Giurgiutiu, Fana Alemseged, Marco Pileggi, Bruce Campbell, Gregory W. Albers, Jeremy J. Heit Source Type: research
Vascular perfusion differs in two distinct PDGFR β-positive zones within the ischemic core of male mice 2 weeks following photothrombotic stroke
J Neurosci Res. 2022 Nov 22. doi: 10.1002/jnr.25146. Online ahead of print.ABSTRACTStroke therapy has largely focused on preventing damage and encouraging repair outside the ischemic core, as the core is considered irreparable. Recently, several studies have suggested endogenous responses within the core are important for limiting the spread of damage and enhancing recovery, but the role of blood flow and capillary pericytes in this process is unknown. Using the Rose Bengal photothrombotic model of stroke, we illustrate blood vessels are present in the ischemic core and peri-lesional regions 2 weeks post stroke in male mic...
Source: Cell Research - November 22, 2022 Category: Cytology Authors: Gary P Morris Emma K Gowing Jo-Maree Courtney Hannah E Coombe Natalie E King Sarah S J Rewell David W Howells Andrew N Clarkson Brad A Sutherland Source Type: research
Human-Derived Hair Follicle Stem Cells and Hydrogen Sulfide on Focal Cerebral Ischemia Model: A Comparative Evaluation of Radiologic, Neurobehavioral and Immunohistochemical Results
In conclusion, intracerebral HFBSC treatment after 24 hour of ischemic stroke may be an effective way to reduce the cranial infarct volume, whereas H2S treatment alone or in combination with HFBSC may not be sufficient for ischemic brain injury.PMID:36410427 | DOI:10.1016/j.brainres.2022.148170
Source: Brain Research - November 21, 2022 Category: Neurology Authors: Cetin Genc Alican Tahta Ece Erdag Ilyas Dolas Selim Sahin Erdal Karaoz Yavuz Aras Pulat Akin Sabanci Source Type: research
Association of pre-mechanical thrombectomy collateral scores with functional outcomes in the early versus extended window for thrombectomy
Conclusions: Our study demonstrates that while several collateral grades are helpful to predict outcomes in patients presenting in the early window, none of the pre-MT collateral scores were associated with outcomes in patients who presented in the extended window for MT. Thus, the current strategy of using perfusion imaging for the selection of patients for MT in the extended window should continue.PMID:36397726 | DOI:10.1177/15910199221138157
Source: Interventional Neuroradiology - November 18, 2022 Category: Radiology Authors: Taha Nisar Osama Abu-Hadid Konrad Lebioda Toluwalase Tofade Priyank Khandelwal Source Type: research
