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Condition: Ischemic Stroke
Nutrition: Antidoxidants

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Total 671 results found since Jan 2013.

Dose-Dependent Effects of Astaxanthin on Ischemia/Reperfusion Induced Brain Injury in MCAO Model Rat
Neurochem Res. 2022 Mar 14. doi: 10.1007/s11064-022-03565-5. Online ahead of print.ABSTRACTExcitotoxicity and oxidative stress are central to the pathology of the nervous system, and inhibition of excitotoxicity induced by glutamate is one of the therapeutic goals determined for stroke. The present study aimed to investigate the effects of Astaxanthin, a potent natural antioxidant, on complications caused by acute cerebral stroke. In this research, 60 male Wistar rats were used which were divided into 5 groups as follow: (1) the sham group (vehicle), (2) the ischemic control group (vehicle), and the ischemic groups treated...
Source: Neurochemical Research - March 14, 2022 Category: Neuroscience Authors: Forough Taheri Ehsan Sattari Maryam Hormozi Hassan Ahmadvand Mohammad Reza Bigdeli Parastou Kordestani-Moghadam Khatereh Anbari Sara Milanizadeh Mehrnoush Moghaddasi Source Type: research

Fraxetin protects rat brains from the cerebral stroke via promoting angiogenesis and activating PI3K/Akt pathway
CONCLUSION: Fraxetin has protective effects on the brain ischemia-reperfusion injury and promotes angiogenesis for cerebral repair via phosphorylation of PI3K and Akt.PMID:35285387 | DOI:10.1080/08923973.2022.2052893
Source: Immunopharmacology and Immunotoxicology - March 14, 2022 Category: Allergy & Immunology Authors: Yuhuan Cui Meihong Liu Li Zuo Haiyan Wang Jian Liu Source Type: research

Is Selenium Supplementation Beneficial in Acute Ischemic Stroke?
This study proposed to investigate the effect of intravenous Se (Selenase) administration in patients with acute ischemic stroke (AIS) on neurological outcomes, antioxidant enzyme activity, and inflammatory marker levels. Methods: AIS patients (n=50) were recruited from a neurology unit of a university-affiliated hospital. Patients were randomly assigned to receive either Selenase or placebo (saline) for 5 days. The modified ranking scale, the national institute of health stroke scale, and the mini-mental state examination, as primary outcomes, and the serum GPx concentration, total antioxidant activity, and tumor n...
Source: The Neurologist - March 1, 2022 Category: Neurology Tags: Original Articles Source Type: research

Melanin nanoparticles enhance the neuroprotection of mesenchymal stem cells against hypoxic-ischemic injury by inhibiting apoptosis and upregulating antioxidant defense
This article is protected by copyright. All rights reserved.PMID:35170135 | DOI:10.1002/cbin.11781
Source: Cell Biology International - February 16, 2022 Category: Cytology Authors: Chunliu Tang Jiefeng Luo Xianjia Yan Qiaojuan Huang Zhenhua Huang Qi Luo Yuan Lan Dingzhi Chen Baolin Zhang Menghua Chen Deyan Kong Source Type: research

Traditional medicine in China for ischemic stroke: bioactive components, pharmacology, and mechanisms
J Integr Neurosci. 2022 Jan 28;21(1):26. doi: 10.31083/j.jin2101026.ABSTRACTIschemic stroke is an acute cerebrovascular disease and the third most common cause of death after ischemic heart disease. Increasing attention is being paid to finding effective treatments through traditional medicine. Thus, studying the traditional medicine for the treatment of ischemic stroke is of great importance. Traditional medicine in China includes traditional Chinese medicine (TCM) and other ethnic medicines, which is rich in variety and resources. This review first introduces the treatment mechanisms associated with ischemic stroke, such...
Source: Journal of Integrative Neuroscience - February 15, 2022 Category: Neuroscience Authors: Min Xu Rui-Xia Wu Xiao-Li Li Yi-Shen Zeng Jia-Yang Liang Ke Fu Yuan Liang Zhang Wang Source Type: research