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Condition: Ischemic Stroke
Education: Study
Procedure: Carotid Endarterectomy
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Total 525 results found since Jan 2013.
Carotid web leads to new thrombus formation: computational fluid dynamic analysis coupled with histological evidence
We describe a 48-year-old woman with carotid web who developed embolic stroke. We obtained a fresh thrombus from the internal carotid artery when carotid endarterectomy was performed. A preoperative computational fluid dynamics (CFD) study showed stagnation of blood around the web structure as well as the low wall shear stress. The rheological analysis newly disclosed mechanisms of thrombus formation related to the carotid web. CFD study in the carotid web may determine indication and timing of surgical interventions with further accumulation of clinical evidence.
Source: Acta Neurochirurgica - March 9, 2020 Category: Neurosurgery Source Type: research
Investigation of S-Nitrosoglutathione in stroke: A systematic review and meta-analysis of literature in pre-clinical and clinical research.
CONCLUSIONS: Pre-clinical studies showed positive benefit of GSNO in animal stroke models. The meta-analysis of clinical studies demonstrated that GSNO is effective in reducing embolic signals in patients with symptomatic internal carotid artery stenosis undergoing carotid endarterectomy or stenting. Further investigation of this molecule is warranted.
PMID: 32119935 [PubMed - as supplied by publisher]
Source: Experimental Neurology - February 27, 2020 Category: Neurology Authors: Liu S, Zheng H, Yu W, Ramakrishnan V, Shah S, Gonzalez LF, Singh I, Graffagnino C, Feng W Tags: Exp Neurol Source Type: research
Prognostic Role of Pre-Operative Symptom Status in Carotid Endarterectomy: A Systematic Review and Meta-Analysis.
CONCLUSION: Patients undergoing CEA after a stroke have worse peri-operative outcomes in terms of stroke and death. Further research needs to be performed to ascertain the value of this finding in risk stratification systems and to investigate potential aetiological associations between pre-operative symptom status and peri-operative risk following a CEA.
PMID: 32081531 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - February 17, 2020 Category: Surgery Authors: Ball S, Ball A, Antoniou GA Tags: Eur J Vasc Endovasc Surg Source Type: research
The impact of pre-operative symptoms on carotid endarterectomy Outcomes: Analysis of the ACS-NSQIP carotid endarterectomy database
Publication date: Available online 1 February 2020Source: Journal of Clinical NeuroscienceAuthor(s): Varun S. Shah, Daniel Kreatsoulas, David Dornbos, Santino Cua, Ciarán J. PowersAbstractCarotid artery stenosis accounts for up to 20% of ischemic strokes. Since the 1950 s, one of the primary surgical treatment for this condition is carotid endarterectomy (CEA). Because of improvement of medical therapy for carotid artery atherosclerosis and the increased use of carotid artery stents, CEA is indicated if the risk of stroke and death are low. The goal of this study is to characterize the impact of pre-operative stroke and ...
Source: Journal of Clinical Neuroscience - February 2, 2020 Category: Neuroscience Source Type: research
Can carotid endarterectomy be performed safely within 14 days after intravenous thrombolysis for acute stroke?
Carotid endarterectomy (CEA) represents a standard procedure in case of symptomatic carotid stenosis of 50-99% within 2 weeks from onset of stroke or transient ischemic symptoms (TIA). The optimal time to perform CEA after Intravenous Thrombolysis (IVT) is still unclear. The aim of this study was to analyze the safety of CEA performed within 2 weeks from IVT.
Source: Annals of Vascular Surgery - January 5, 2020 Category: Surgery Authors: Giuseppe Deiana, Antonio Baule, Patrizia Dalla Caneva, Genadi Genadiev Georgiev, Jorge Samuel Cabrera Morales, Antonio Manca, Stefano Camparini Tags: Clinical Research, Basic Science Source Type: research
Can Carotid Endarterectomy be Performed Safely within 14 days after Intravenous Thrombolysis for Acute Stroke?
Carotid endarterectomy (CEA) represents a standard procedure in case of symptomatic carotid stenosis of 50 –99% within 2 weeks from onset of stroke or transient ischemic attack (TIA) symptoms. The optimal time to perform CEA after intravenous thrombolysis (IVT) is still unclear. The aim of this study was to analyze the safety of CEA performed within 2 weeks from IVT.
Source: Annals of Vascular Surgery - January 5, 2020 Category: Surgery Authors: Giuseppe Deiana, Antonio Baule, Patrizia Dalla Caneva, Genadi Genadiev Georgiev, Jorge Samuel Cabrera Morales, Antonio Manca, Stefano Camparini Tags: Clinical Research Source Type: research
Perioperative Stroke in Carotid Artery Stenting as a Surrogate Marker and Predictor for 30-day Postprocedural Mortality & #8211; A Pooled Analysis of 156,000 Patients with Carotid Artery Disease
Conclusions: Perioperative stroke drastically increases the risk of 30-day mortality. The occurrence of perioperative stroke exhibited high specificity but modest sensitivity in predicting 30-day mortality following CAS. This highlights the importance of neurophysiologic monitoring to detect intraoperative cerebral ischemia and perform timely interventions.
Source: Neurology India - December 19, 2019 Category: Neurology Authors: Ahmed M Altibi Eyad E Saca Harbir Dhillon Parthasarathy D Thirumala Source Type: research
Results of Carotid Endarteriectomy under Locoregional Anesthesia in acute Ischemic Stroke with Watershed zone Infarction Population
Introduction: Cerebral border zone infarctions (Watershed infarctions) on the early postoperative outcomes of patient undergoing carotid endarterectomy (CEA) were associated, in several studies, with a higher neurological complication rate. The current hypothesis is that hemodynamic phenomenon is involved. CEA performed under locoregional anesthesia enable to instantly reveal any hemodynamic phenomenon.
Source: European Journal of Vascular and Endovascular Surgery - November 30, 2019 Category: Surgery Authors: Nicolas Bouchareine, Maud Esteban-Madder, Hanan Alhazmi, Philippe Tresson, Nellie Dellaschiava, Antoine Millon Source Type: research
Start of Antiplatelet Therapy Increases the Prevalence of Intraplaque Hemorrhage in Patients With Advanced Carotid Artery Lesions: A Longitudinal MR Imaging Study
Introduction: Intraplaque hemorrhage (IPH) is an important feature of plaque vulnerability. Patients with a history of transient ischemic attack or stroke are treated with platelet aggregation inhibitors to prevent secondary myocardial infarction or ischemic stroke. Although antiplatelet medication is effective in reduction of clot formation, it also has adverse effects. It has therefore been hypothesized that platelet aggregation inhibitors could also initiate the onset or progression of IPH. A histopathological study on 154 carotid endarterectomy plaques found that preoperative antiplatelet therapy was associated with an...
Source: European Journal of Vascular and Endovascular Surgery - November 30, 2019 Category: Surgery Authors: Genevi ève Crombag, Madieke Liem, Eline Koornstra, Floris Schreuder, Dianne Nolen-van Dam, Carlo Lucci, Rob van der Geest, Mat Daemen, Anton van der Steen, Jeroen Hendrikse, Werner Mess, Aad van der Lugt, Joachim Wildberger, Robert van Oostenbrugge, Paul Source Type: research
Early and Long-term Impact of Postoperative Cerebrovascular Complications After Carotid Endarterectomy
Introduction: The rate of postoperative cerebrovascular complications (PCC), such as stroke and transient ischemic attack (TIA), associated with carotid endarterectomy (CEA) is generally lower than 3% for asymptomatic and 5% for symptomatic patients in the literature; however, few studies analyzed the impact of PCC on long-term outcome of patients submitted to CEA. The aim of the study was to identify predictors of PCC occurrence and to evaluate these patients in terms of survival, recurrences and clinical status at follow-up.
Source: European Journal of Vascular and Endovascular Surgery - November 30, 2019 Category: Surgery Authors: Andrea Vacirca, Gianluca Faggioli, Rodolfo Pini, Mortalla Dieng, Antonino Maria Logiacco, Enrico Gallitto, Chiara Mascoli, Michele Mirelli, Mauro Gargiulo Source Type: research
CAR 3. Neurologic Complication Rates of Intravenous Thrombolysis Combined With Early Carotid Endarterectomy for Treatment of Hyperacute Ischemic Stroke
Intravenous thrombolysis for treatment of acute carotid-associated stroke can be combined with carotid endarterectomy (CEA) either simultaneously or in a staged procedure. The aim of this single-center retrospective study was to analyze the short-term and long-term results of sequential lysis with CEA.
Source: Journal of Vascular Surgery - October 21, 2019 Category: Surgery Authors: Ewa Swiecka, Martin Storck, Roland Zippel Source Type: research
Magnetic Resonance Imaging Identified Brain Ischaemia in Symptomatic Patients Undergoing Carotid Endarterectomy Is Related to Histologically Apparent Intraplaque Haemorrhage.
CONCLUSION: Symptomatic patients with ipsilateral carotid stenosis and silent brain ischaemia on pre-operative MR-DWI, more often showed pathological evidence of IPH compared with those without ischaemic lesions. This identifies carotid IPH as a marker for patients at risk of silent brain ischaemia and possibly for future stroke and other arterial disease complications. Such patients may be more likely to benefit from CEA than those without evidence of ipsilateral carotid IPH.
PMID: 31631008 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - October 16, 2019 Category: Surgery Authors: Rots ML, Timmerman N, de Kleijn DPV, Pasterkamp G, Brown MM, Bonati LH, de Borst GJ Tags: Eur J Vasc Endovasc Surg Source Type: research
Staged Carotid Artery Stenting and Coronary Artery Bypass Grafting Procedures: A Word of Caution
In their systematic review and meta-analysis (n=5 studies; 16,712 patients), Giannopoulos et al.1 compared synchronous carotid endarterectomy (CEA) and coronary artery bypass grafting (CABG) vs. staged carotid artery stenting (CAS) followed by CABG. They demonstrated that perioperative stroke (3% [447/15,727] vs. 3% [33/985], for CEA/CABG vs. CAS/CABG, respectively; odds ratio [OR]: 0.84; 95% confidence interval [CI]: 0.43-1.64; I2=39.1%) and transient ischemic attack (TIA) rates (1% [2/193] vs 4% [4/95] for CEA/CABG vs.
Source: Annals of Vascular Surgery - October 13, 2019 Category: Surgery Authors: Kosmas I. Paraskevas Tags: Correspondence Source Type: research
CEA vs stent in patients with acute strokes: are they equally effective?
CONCLUSIONS: Carotid endarterectomy continues to demonstrate effectiveness and safety for management of acute strokes, while carotid stenting has limitations. Carotid artery stenting has been shown to be non-inferior in some patient populations, but more recent and future technologic developments may expand the potential acceptable patient selection criteria.
PMID: 31603298 [PubMed - as supplied by publisher]
Source: The Journal of Cardiovascular Surgery - October 8, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Caliste X, Laser A, Darling RC Tags: J Cardiovasc Surg (Torino) Source Type: research
Is size of infarct or clinical picture that should delay urgent carotid endarterectomy? A meta-analysis.
CONCLUSIONS: CEA for patients with a recent stroke is associated with 5.4% and 7.9% of stroke/death. A large volume of the cerebral ischemic lesion and a deteriorated neurological status are associated with a higher perioperative risk; urgent carotid revascularization seems to further increase this risk.
PMID: 31603297 [PubMed - as supplied by publisher]
Source: The Journal of Cardiovascular Surgery - October 8, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Pini R, Faggioli G, Vacirca A, Dieng M, Fronterrè S, Gallitto E, Mascoli C, Stella A, Gargiulo M Tags: J Cardiovasc Surg (Torino) Source Type: research
