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Perioperative Antiplatelet Bridging With Cangrelor: A Cohort Study and Narrative Review
CONCLUSION AND RELEVANCE: This study suggests that cangrelor bridging may be a reasonable alternative to holding oral P2Y12 inhibitors in patients requiring interruption of antiplatelet therapy for an urgent surgery/invasive procedure.PMID:36004393 | DOI:10.1177/10600280221120310
Source: The Annals of Pharmacotherapy - August 25, 2022 Category: Drugs & Pharmacology Authors: Alok Salgia Chelsea K Krueger Michael A Gillette Source Type: research

Embolic Events After Computed Tomography Contrast Injection in Patients With Interatrial Shunts: A Cohort Study
Conclusion: Among patients with echocardiographic evidence of an interatrial shunt, IV CT contrast administration without an in-line filter does not increase the incidence of cardiac or neurological events.
Source: Journal of Thoracic Imaging - August 25, 2022 Category: Radiology Tags: Original Articles Source Type: research

Ticagrelor with and without aspirin in patients with a prior coronary artery bypass graft undergoing percutaneous coronary intervention: the TWILIGHT-CABG study
CONCLUSIONS: In high-risk patients with prior CABG, ticagrelor monotherapy reduced bleeding without compromising ischaemic outcomes compared with ticagrelor plus aspirin.PMID:35979636 | DOI:10.4244/EIJ-D-22-00319
Source: EuroIntervention - August 18, 2022 Category: Cardiovascular & Thoracic Surgery Authors: Gennaro Sardella Frans J Beerkens George Dangas Davide Cao Usman Baber Samantha Sartori David J Cohen Carlo Briguori Robert Gil Johny Nicolas Zhongjie Zhang Dariusz Dudek Vijay Kunadian Ran Kornowski Giora Weisz Bimmer Claessen Steven O Marx Javier Escane Source Type: research

Characteristics and Outcomes of Candidemia in Patients with Durable Left Ventricular Assist Device Support
In conclusion, fungemia is a rare and severe complication in LVAD patients occurring early postimplant.
Source: ASAIO Journal - August 1, 2022 Category: Medical Devices Tags: Adult Circulatory Support Source Type: research

LB003 Multicenter assessment of the tigertriever 13 for thrombectomy in primary medium vessels occlusions
ConclusionMechanical thrombectomy using the Tigertriever13 appears to be safe and effective for MeVO among different centers and physicians, as a first-line device or as a recue-therapy after an other approach failure.Disclosures A. guenego: 6; C; Travel Grant to PAIRS in Dubai by Rapid Medical. B. lubicz: None. A. Dmytriw: None. R. Regenhardt: None. J. diestro: None. V. pereira: None. P. jabbour: None. J. siegler: None. N. gonzalez: None. M. Levitt: None. I. Tancredi: None. A. Rouchaud: None. J. Fiehler: None. T. Faizy: None. P. Kan: None. X. barreau: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2022 Category: Neurosurgery Authors: Guenego, A., Lubicz, B., Dmytriw, A., Regenhardt, R., Diestro, J., Pereira, V., Jabbour, P., Siegler, J., Gonzalez, N., Levitt, M., Tancredi, I., Rouchaud, A., Fiehler, J., Faizy, T., Kan, P., Barreau, X. Tags: SNIS 19th annual meeting late-breaking oral abstracts Source Type: research

E-095 First-pass effect predicts clinical outcome and infarct growth after thrombectomy for distal medium vessel occlusions
Conclusion mFPE is associated with better clinical outcomes and lower stroke progression in DMVO.Disclosures A. Guenego: None. B. Lubicz: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Guenego, A., Lubicz, B. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

E-200 Predictors of good clinical outcome after thrombectomy for distal medium vessel occlusions
ConclusionAn older age, a longer puncture to recanalization time and a higher baseline core volume were strongly associated with poor clinical outcomes, while successful recanalization (mTICI 2c-3) was associated with better outcomes after MT for DMVO.Disclosurse A. Guenego: None. B. Lubicz: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Guenego, A., Lubicz, B. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

E-215 Single stent assisted coiling for wide neck bifurcation aneurysms: a multi-center core lab validated analysis demonstrating safety and efficacy
ConclusionThis study represents the first multi-center, core-lab validated data of the safety and efficacy of the L-stenting single stent technique for wide-neck bifurcation aneurysms. Further prospective studies in larger cohorts are necessary to compare the efficacy and safety of this treatment to other endovascular techniques for treatment of wide neck bifurcation aneurysms.Disclosures N. Siddiqui: None. R. De Leacy: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Siddiqui, N., De Leacy, R. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

Clinical characteristics and outcomes of ischemic stroke patients during Ramadan vs. non-Ramadan months: Is there a difference?
ConclusionBased on our results, there was no difference, in general, between patients with IS during Ramadan and non-Ramadan months. However, IS patients had higher NIHSS scores at discharge and more ICU admissions during Ramadan. Last, we suggest future studies with larger sample sizes, longer duration, and including all types of strokes.
Source: Frontiers in Neurology - July 22, 2022 Category: Neurology Source Type: research

Outcomes of endovascular thrombectomy in patients selected by computed tomography perfusion imaging - a matched cohort study comparing nonagenarians to younger patients
Conclusions Nonagenarians were noted to have greater mortality and sICH rates following EVT compared with matched younger patients, which may be ameliorated by selecting patients with smaller CTP core volumes. Nonagenarians undergoing EVT had similar rates of successful reperfusion and functional independence compared with the younger cohort.
Source: Journal of NeuroInterventional Surgery - July 14, 2022 Category: Neurosurgery Authors: Rahangdale, R., Hackett, C. T., Cerejo, R., Fuller, N. M., Malhotra, K., Williamson, R., Hentosz, T., Tayal, A. H., Rana, S. S. Tags: Editor''s choice, Ischemic stroke Source Type: research

Early Intracranial Hemorrhage Predicts Poor Clinical Outcome in Community-Acquired Bacterial Meningitis
ConclusionEarly cerebral hemorrhage (ECHO) is a potential prognostic marker for clinicians confronted with decision-making in patients who are critically ill with community-acquired bacterial meningitis.
Source: Frontiers in Neurology - June 16, 2022 Category: Neurology Source Type: research

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