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E-176 Endovascular stent retriever thrombectomy of medium and small vessel occlusion of the middle cerebral artery with acute ischemic stroke: a case series
ConclusionsOur case series demonstrated that SRMT in SVO with disabling NIHSS is feasible and safe if performed carefully. All patient achieved TICI 3 perfusion and first pass effect was better observed in trap technique and use of long solitaire STD. Good function outcomes were achieved in all cases irrespective of the types of SRD used and passes required to achieve TICI 3 perfusion. Further studies are required.Disclosures Y. Lodi: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Lodi, Y. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

Dual antiplatelet use in the management of COVID-19 associated acute ischemic stroke reocclusion
CONCLUSION: COVID-19 AIS may be associated with a hypercoagulable state which risks malignant reocclusion complicating MT. We found antithrombotic treatment periprocedural cangrelor with or without argatroban transitioned to oral aspirin with ticagrelor to be a viable method for management of these patients.PMID:35549746 | DOI:10.1177/15910199221097484
Source: Interventional Neuroradiology - May 13, 2022 Category: Radiology Authors: Joshua Feler Carlin Chuck Matthew Anderson Jonathan Poggi Joseph Sweeney Krisztina Moldovan Mahesh V Jayaraman Ryan McTaggart Radmehr Torabi Source Type: research

Asymptomatic Carotid Stenosis Is Associated With Circadian and Other Variability in Embolus Detection
Conclusions: Embolism associated with asymptomatic carotid stenosis shows circadian variation with highest rates 4–6 h before midday. This corresponds with peak circadian incidence of stroke and other vascular complications. These and ASED Study results show that monitoring frequency, duration, and time of day are important in ES detection. Introduction Transcranial Doppler (TCD) detected microembolism in the ipsilateral middle cerebral artery (MCA) may help stratify the risk of stroke and other arterial disease complications in persons with advanced (≥60%) asymptomatic carotid stenosis. If so, this t...
Source: Frontiers in Neurology - April 15, 2019 Category: Neurology Source Type: research

P-010 Practice variations in addressing acute tandem carotid occlusions in emergent large vessel occlusion strokes
Conclusion For tandem occlusions with cervical ICA involvement, acute stenting with adjunctive angioplasty, is a current prevailing practice for recanalization of the extracranial ICA. There is considerable variability in antiplatelet protocols, with a slight favoring of the administration of loading doses of aspirin and clopidogrel before stent deployment. Variability is also present for anesthesia, with general anesthesia having a significant role. Disclosures S. Coffman: None. S. Trott: None. A. Alhajeri: None. J. Fraser: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Coffman, S., Trott, S., Alhajeri, A., Fraser, J. Tags: Oral Poster Abstracts Source Type: research

Natural History and Management of Blunt Traumatic Pseudoaneurysms of the Internal Carotid Artery: The Harborview Algorithm Based Off a 10-Year Experience
Conclusions: Traumatic ICA pseudoaneurysms are safely treated with daily aspirin, embolic monitoring, and radiographic surveillance. Acute stroke or hemorrhage, or delayed radiographic progression, are indications for endovascular or surgical treatment.
Source: Annals of Surgery - March 5, 2016 Category: Surgery Tags: Original Articles Source Type: research

Statin Therapy Does Not Affect the Radiographic and Clinical Profile of Patients with TIA and Minor Stroke EDITOR'S CHOICE
CONCLUSIONS: Prestroke or early-stroke statin therapy was not associated with a reduction in the number of DWI lesions, infarct volume, or improved clinical or functional outcome at 3 months. The effect of acute statin treatment in patients with ischemic stroke/TIA remains unclear and needs further investigation.
Source: American Journal of Neuroradiology - June 11, 2015 Category: Radiology Authors: Asdaghi, N., Coulter, J. I., Modi, J., Camden, M. C., Qazi, A., Goyal, M., Rundek, T., Coutts, S. B. Tags: EDITOR ' S CHOICE Source Type: research

Cervical Artery Dissections in the Vancouver General Hospital (VGH) Stroke Database: A common stroke mechanism? (P5.161)
Conclusion: In this preliminary review, we have identified 26 patients with CAD in the first 6 months of our database collection. Although these results are from a single centre, this incidence of cervical artery dissection is much higher than expected. This analysis is ongoing and we will assess race-ethnicity, presenting features and preceding history of trauma and infection.Disclosure: Dr. Wilson has nothing to disclose. Dr. Salmeen has nothing to disclose. Dr. Field has received personal compensation in an editorial capacity for Postgraduate Medicine. Dr. Yip has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Wilson, L., Salmeen, A., Field, T., Yip, S. Tags: Cerebrovascular Disease and Interventional Neurology: Dissection Source Type: research

Clinical and radiographic outcomes following traumatic Grade 3 and 4 carotid artery injuries: a 10-year retrospective analysis from a Level 1 trauma center. The Parkland Carotid and Vertebral Artery Injury Survey.
CONCLUSIONS Although the posttraumatic cerebral infarction rate may be overestimated, the results of this study suggest that the Grade 3 and 4 BCAIs carry the highest stroke risk of the blunt cerebrovascular injuries, and those infarctions were identified on or shortly after hospital admission. Despite a 40% recanalization rate in the Grade 4 BCAI group and an 89% rate of persistent pseudoaneurysm in the Grade 3 BCAI group, follow-up imaging showed progressive worsening without radiographic improvement in only a small number of patients, and these findings alone did not correlate with adverse clinical outcome. Follow-up pr...
Source: Journal of Neurosurgery - December 19, 2014 Category: Neurosurgery Authors: Scott WW, Sharp S, Figueroa SA, Eastman AL, Hatchette CV, Madden CJ, Rickert KL Tags: J Neurosurg Source Type: research

Clinical and radiological outcomes following traumatic Grade 3 and 4 vertebral artery injuries: a 10-year retrospective analysis from a Level I trauma center. The Parkland Carotid and Vertebral Artery Injury Survey.
CONCLUSIONS The majority of high-grade blunt VA injuries remain stable or are improved at final follow-up. Despite a 4% rate of radiographic worsening in the Grade 3 blunt VA injury group and a 35% recanalization rate in the Grade 4 blunt VA injury group, there were no adverse clinical outcomes associated with these radiographic changes. No cerebral infarctions were noted in the Grade 3 group. A 7% stroke rate was identified in the Grade 4 blunt VA injury group; however, this was confined to the immediate postinjury period and was associated with 100% mortality. While these data suggest that these high-grade vertebral arte...
Source: Journal of Neurosurgery - October 24, 2014 Category: Neurosurgery Authors: Scott WW, Sharp S, Figueroa SA, Eastman AL, Hatchette CV, Madden CJ, Rickert KL Tags: J Neurosurg Source Type: research

Extracranial traumatic aneurysms due to blunt cerebrovascular injury.
Conclusions The majority of traumatic aneurysms can be managed with an antiplatelet regimen of 325 mg aspirin daily and serial imaging. Saccular aneurysms have a greater tendency to enlarge when compared with fusiform aneurysms. PMID: 24702325 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - April 4, 2014 Category: Neurosurgery Authors: Foreman PM, Griessenauer CJ, Falola M, Harrigan MR Tags: J Neurosurg Source Type: research

Is There an Increased Risk of Intracranial Hemorrhage When Treating Patients Who Are Currently on Dual Anti-Platelets with IV tPA? (P01.233)
CONCLUSIONS: In our cohort, there was no additional risk of hemorrhagic complications in patients on dual antiplatelet therapy who received IVtPA, prospective studies are needed to confirm this finding.Disclosure: Dr. Kung has nothing to disclose. Dr. Korsnack has nothing to disclose. Dr. Zaidi has nothing to disclose. Dr. Jumaa has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Kung, V., Korsnack, A., Zaidi, S., Jumaa, M. Tags: P01 Cerebrovascular Disease I Source Type: research