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Condition: Sleep Disorders
Drug: Melatonin

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Total 28 results found since Jan 2013.

How People With Diabetes Can Lower Stroke Risk
After spending nearly two decades trying to manage her Type 2 diabetes, Agnes Czuchlewski landed in the emergency room in 2015, with news that she’d just experienced a heart attack. She also learned that she had metabolic syndrome, a cluster of conditions that includes diabetes but also brings higher risk of heart disease and stroke. “Because I needed to lose quite a bit of weight when I was first diagnosed, I was focused on the number I saw on the scale, and then on my blood-sugar numbers,” recalls Czuchlewski, 68, who lives in New York City. “I didn’t realize other numbers came into play, li...
Source: TIME: Health - November 10, 2022 Category: Consumer Health News Authors: Elizabeth Millard Tags: Uncategorized Disease healthscienceclimate Source Type: news

Melatonin and Ischemic Stroke: Mechanistic Roles and Action.
Authors: Andrabi SS, Parvez S, Tabassum H Abstract Stroke is one of the most devastating neurological disabilities and brain's vulnerability towards it proves to be fatal and socio-economic loss of millions of people worldwide. Ischemic stroke remains at the center stage of it, because of its prevalence amongst the several other types attacking the brain. The various cascades of events that have been associated with stroke involve oxidative stress, excitotoxicity, mitochondrial dysfunction, upregulation of Ca(2+) level, and so forth. Melatonin is a neurohormone secreted by pineal and extra pineal tissues responsibl...
Source: Advances in Pharmacological Sciences - October 6, 2015 Category: Drugs & Pharmacology Tags: Adv Pharmacol Sci Source Type: research

Oversleeping: The Effects and Health Risks of Sleeping Too Much
This article originally appeared on the Amerisleep blog. Rosie Osmun is the Creative Content Manager at Amerisleep, a progressive memory foam mattress brand focused on eco-friendly sleep solutions. Rosie writes more posts on the Amerisleep blog about the science of sleep, eco-friendly living, leading a healthy lifestyle and more. -- This feed and its contents are the property of The Huffington Post, and use is subject to our terms. It may be used for personal consumption, but may not be distributed on a website.
Source: Healthy Living - The Huffington Post - January 29, 2016 Category: Consumer Health News Source Type: news

Melatonin supplementation in the subacute phase after ischemia alleviates postischemic sleep disturbances in rats
ConclusionsMelatonin promptly reversed ischemia-induced sleep disturbances. The neuroprotective effects of melatonin on ischemic injury may be partially associated with its role in sleep modulation.
Source: Brain and Behavior - September 14, 2021 Category: Neurology Authors: Shu ‐Mei Hao, Zhi‐Gang Zhong, Wei‐Min Qu, Zhi‐Li Huang, Feng‐Yan Sun, Mei‐Hong Qiu Tags: ORIGINAL ARTICLE Source Type: research

Mortality of Shift Workers
This study strengthens the evidence of a connection between shift work and all-cause mortality. It also provides support for an association between shift work and mortality of cardiovascular disease. The mechanisms responsible for the association between shift work and disease are probably co mplex and influenced by genetics, lifestyle, sleep, social stress, and disturbed circadian rhythms (7). Further epidemiological studies and experimental studies are needed to explain the causal pathways. One issue would be to find a better variable measuring the circadian phase. Shift work is not a valid proxy since previous studies...
Source: Scandinavian Journal of Work, Environment and Health - January 25, 2017 Category: Occupational Health Tags: Editorial Source Type: research

What Medications Prevent Delirium in Elderly Medical Inpatients?
This study demonstrated lower rates of delirium in the melatonin arm, with an impressive number needed to treat (NNT) below six patients; mortality and length of hospital stay were unaffected.3 A delirium-prevention effect of melatonin has not been reproduced in other studies, notably Jaiswal et al, which randomized patients to a placebo or 3 mg of melatonin and found no difference in rates of delirium prevention.7  The melatonin receptor agonist ramelteon also has small but favorable evidence for preventing non-ICU hospitalized delirium. This comes from a study of 67 patients aged 65 years or older who were randomized to...
Source: The Hospitalist - May 2, 2022 Category: Hospital Management Authors: Ronda Whitaker Tags: Drug Therapy Geriatrics Key Clinical Questions Medication Source Type: research

Stroke and pineal gland calcification: Lack of association. Results from a population-based study (The Atahualpa Project)
The pineal gland has been the subject of myths and misconceptions over the years. These ranged from the ancient belief that it is the “seat of the soul” (René Descartes, 1596-1650), to more recent hypotheses suggesting that pineal dysfunction is associated with sense of direction loss [1] or that calcifications of the gland are less prevalent in underdeveloped societies [2]. Current knowledge indicates that the main function of the pineal gland is to secrete melatonin, a hormone primarily associated with timing of circadian rhythms and control of the sleep-wake cycle [3].
Source: Clinical Neurology and Neurosurgery - January 5, 2015 Category: Neurosurgery Authors: Oscar H. Del Brutto, Robertino M. Mera, Julio Lama, Mauricio Zambrano Source Type: research

The effect of blue-blocking intraocular lenses on circadian biological rhythm: protocol for a randomised controlled trial (CLOCK-IOL colour study)
Introduction Blue light information plays an important role in synchronising internal biological rhythm within the external environment. Circadian misalignment is associated with the increased risk of sleep disturbance, obesity, diabetes mellitus, depression, ischaemic heart disease, stroke and cancer. Meanwhile, blue light causes photochemical damage to the retina, and may be associated with age-related macular degeneration (AMD). At present, clear intraocular lenses (IOLs) and blue-blocking IOLs are both widely used for cataract surgery; there is currently a lack of randomised controlled trials to determine whether clear...
Source: BMJ Open - May 12, 2015 Category: Journals (General) Authors: Nishi, T., Saeki, K., Obayashi, K., Miyata, K., Tone, N., Tsujinaka, H., Yamashita, M., Masuda, N., Mizusawa, Y., Okamoto, M., Hasegawa, T., Maruoka, S., Ueda, T., Kojima, M., Matsuura, T., Kurumatani, N., Ogata, N. Tags: Open access, Epidemiology, Ophthalmology Protocol Source Type: research

7 Big Things We Learned About Sleep In The Past Decade
It's no secret that here at The Huffington Post, we love sleep -- and for good reason. Sleep has been called the "third pillar" of health, along with nutrition and exercise. Getting the quality sleep that you need has the power to protect your physical and mental health, while skipping out on sleep can seriously hurt your health, cognition and well-being over time. Over the past 10 years, sleep has finally become widely recognized as a critical aspect of good health, and new research has shed more light on its importance in our lives. Here's what we've learned. 1. A sleeping brain is an active brain. While you're re...
Source: Science - The Huffington Post - May 25, 2015 Category: Science Source Type: news

Lessons Learned From Trends in Insufficient Sleep Across the United States
This article originally appeared on the Amerisleep blog. Rosie Osmun is the Creative Content Manager at Amerisleep, a progressive memory foam mattress brand focused on eco-friendly sleep solutions. Rosie writes more posts on the Amerisleep blog about the science of sleep, eco-friendly living, leading a healthy lifestyle and more. -- This feed and its contents are the property of The Huffington Post, and use is subject to our terms. It may be used for personal consumption, but may not be distributed on a website.
Source: Healthy Living - The Huffington Post - October 16, 2015 Category: Consumer Health News Source Type: news

10 Sleep Technologies: How Much Snore for the Dollar?
Do you want better sleep? Of course you do. You know how bad it is to miss out on sleep, so it can feel like insult added to injury to read yet another newfound, devastating consequence of insufficient sleep: heart disease, heart attack, high blood pressure, stroke, diabetes, mental impairment, etc. And the list is expanding almost daily as researchers learn more. There are "easy" actions that may aid with sleep. Relaxation activities like meditation or chamomile tea are useful for some. Setting and sticking to a waking and sleeping schedule, creating a bedroom retreat, and making a list of worries before turning in can he...
Source: Healthy Living - The Huffington Post - October 27, 2015 Category: Consumer Health News Source Type: news

Vitamin D Deficiency Is As Dangerous As Smoking
The advice you’re getting from your doctor, the TV and even the Surgeon General is so wrong, it’s scary. They’re all busy telling you to stay out of the sun. But Swedish researchers recently discovered that nonsmokers who avoid the sun have a life expectancy similar to smokers who spend a lot of time in the sun. Staying out of the sun is as dangerous as smoking.1 It doesn’t surprise me. I tell all my patients sunlight exposure is essential to our health because it is the best source of vitamin D… possibly the most important nutrient we know of. Mainstream medicine still doesn’t recognize th...
Source: Al Sears, MD Natural Remedies - May 19, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Health Source Type: news

Why Every Woman Needs A Good Night's Rest
When I began writing in this spot three years ago, the headline of my very first entry was, "Getting Enough Sleep Is Smart, Not Selfish." That post went up at a time when Americans were beginning to focus more on a good night's rest. The subject came into a sharper focus, in part, because wearable technology gave us some specifics. Forget the anecdotal evidence of whether we slept well; with the touch of a button, we could know what time we fell asleep, how long we were out and how often our sleep was interrupted. The study of sleep -- and conversations around it -- began gaining traction. Among those paying keen attenti...
Source: Healthy Living - The Huffington Post - July 11, 2016 Category: Consumer Health News Source Type: news

Sleep Deprivation Is Killing You And Your Career
The next time you tell yourself that you'll sleep when you're dead, realize that you're making a decision that can make that day come much sooner. Pushing late into the night is a health and productivity killer. The short-term productivity gains from skipping sleep to work are quickly washed away by the detrimental effects of sleep deprivation on your mood, ability to focus, emotional intelligence, and access to higher-level brain functions for days to come. The negative effects of sleep deprivation are so great that people who are drunk outperform those lacking sleep. Why You Need Adequate Sleep to Perform We've always...
Source: Healthy Living - The Huffington Post - September 17, 2016 Category: Consumer Health News Source Type: news