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Heart-disease risk soars after COVID — even with a mild case
Nature, Published online: 10 February 2022; doi:10.1038/d41586-022-00403-0Massive study shows a long-term, substantial rise in risk of cardiovascular disease, including heart attack and stroke, after a SARS-CoV-2 infection.
Source: Nature AOP - February 10, 2022 Category: Research Source Type: research

COVID-19's Clinical-Pathological Evidence in Relation to Its Repercussion on the Central and Peripheral Nervous System
CONCLUSION: The neurological implications of COVID-19 range from initial symptoms, such as headache, to serious complications, such as ischemic stroke. Although the pathogenesis of neurological phenomena requires further studies, targeted management of the patient is feasible, considering agility in recognizing the infection. Therefore, medical precaution and clinical reasoning are emphasized when providing services to the patient.PMID:35137375 | DOI:10.1007/978-3-030-85113-2_11
Source: Advances in Experimental Medicine and Biology - February 9, 2022 Category: Research Authors: Amanda Menezes Morgado Ana Luiza Menezes Santana Bezerra Esther Barbosa Gon çalves Felix Jos é Correia Saraiva Júnior Nat ália Bitú Pinto Modesto Leite Rolim Neto Ana Lu íza de Aguiar Rocha Martin Source Type: research

SARS-CoV-2: Pathogenic Mechanisms and Host Immune Response
Adv Exp Med Biol. 2021;1313:99-134. doi: 10.1007/978-3-030-67452-6_6.ABSTRACTSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense RNA coronavirus responsible for the COVID-19 pandemic. Since December 2019, coronavirus disease 2019 (COVID-19) has affected more than 127 million people, 2.7 million deaths globally (as per WHO dashboard, dated 31 March, 2020), the virus is capable of transmitting from human to human via inhalation of infected respiratory droplets or aerosols or contact with infected fomites. Clinically, patients with COVID-19 present with severe respiratory distress synd...
Source: Advances in Experimental Medicine and Biology - October 18, 2021 Category: Research Authors: Hadida Yasmin Sudipta Saha Mariam Tariq Butt Rishab Kumar Modi Andrew J T George Uday Kishore Source Type: research

Central Nervous System Outcomes of COVID-19
The worldwide pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected an estimated 200 million people with over 4 million deaths. Although COVID-19, the disease caused by the SARS-CoV-2 virus, is primarily a respiratory disease, an increasing number of neurologic symptoms have been reported. Some of these symptoms, such as loss of smell or taste, are mild and non-life threatening, while others, such as stroke or seizure, are more critical. Many of these symptoms remain long after the acute illness has passed, a phenomenon known as “long COVID” or Post-Acute Sequelae of SARS-CoV-2 infection (PASC).
Source: Translational Research - September 30, 2021 Category: Research Authors: Margaret F. Doyle Source Type: research

Interpretation of myocardial injury subtypes in COVID-19 disease per fourth version of universal definition of myocardial infarction
Conclusions: Objective description of myocardial injury according to the 4th UDMI in current COVID-19 pandemic is crucial in order to discriminate patients with acute myocardial infarction and acute, chronic or incident myocardial injury.PMID:33998352 | DOI:10.1080/1354750X.2021.1921031
Source: Biomarkers - May 17, 2021 Category: Research Authors: Christian Salbach Matthias Mueller-Hennessen Moritz Biener Kiril Stoyanov Michael Preusch Lars Kihm Uta Merle Paul Schnitzler Hugo A Katus Evangelos Giannitsis Source Type: research

COVID-19-Associated Acute Brain Dysfunction Related to Sepsis
J Clin Med Res. 2021 Feb;13(2):82-91. doi: 10.14740/jocmr4437. Epub 2021 Feb 25.ABSTRACTIn global term, as of November 30, 2020, over 30 million people has been infected by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and more than 10,000,000 of them died of acute organ failure. Our reviews have shown that coronavirus disease 2019 (COVID-19) patients with pneumonia and acute respiratory distress syndrome (ARDS) have life-threatening acute brain dysfunction (ABD), ranging from altered mental status/delirium to stupor/coma. Altered mental status/delirium was the most common manifestation of ABD cause...
Source: Clin Med Res - March 22, 2021 Category: Research Authors: Dao Ming Tong Ye Ting Zhou Yuan Wei Wang Source Type: research

Neurological Complications of the COVID-19 Pandemic: What Have We Got So Far?
Adv Exp Med Biol. 2021;1321:21-31. doi: 10.1007/978-3-030-59261-5_2.ABSTRACTThe recently emerged coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal agent of COVID-19, is the newest threat to human health. It has already infected more than 54.5 million people worldwide, currently leading to more than 1.3 million deaths. Although it causes a mild flu-like disease in most patients, lethality may increase to more than 20% in elderly subjects, especially in those with comorbidities, like hypertension, diabetes, or lung and cardiac disease, and the mechanisms are still elusive. Common symp...
Source: Advances in Experimental Medicine and Biology - March 3, 2021 Category: Research Authors: Isabelle Pastor Bandeira Marco Ant ônio Machado Schlindwein Leticia Caroline Breis Jean Pierre Schatzmann Peron Marcus Vin ícius Magno Gonçalves Source Type: research

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